Ukukhathazeka kweGluten kunokudala iimpawu zokugaya, ukukhathala, ezinye iingxaki
Ubuninzi be- gluten nobutyebi bunokuchaphazela phantse yonke inkqubo emzimbeni wakho, kunye neempawu ezibandakanya umonakalo wokugaya, iingxaki zesikhumba ezinjengeengqungquthela, inkohlakalo yengqondo, intlungu edibeneyo kunye nokugqithisa kwimida yakho, ngokutsho koogqirha abaphanda ngolu hlobo.
Ukuba ucinga ukuba ezo zimpawu zivakala kakhulu njengeempawu zesifo se-celiac , ulungile.
Enyanisweni, akunakwenzeka ukwahlula phakathi kwentsholongwane ye-gluten kunye nesifo se-celiac ngenxa yezibonakaliso zodwa- ezi zimbini zikhoyo kunye neempawu ezikufutshane, iingcali kwi-gluten sensitivity zithetha.
Ukwenza izinto zidideke ngakumbi, izifo ze-celiac kunye ne-non-celiac ye-gluten uzwela yizona kuphela iintlobo ze " gluten allergies " ezinokwenzeka. Kukho, ngokwenene, iintlobo ezintlanu ze "gluten allergies," kunye neendidi ezahlukahlukeneyo ezibonisa ukuba unokuba neengxaki ze-gluten .
Yintoni eyiyo iGluten yokuqonda?
Buyela kwi-non-celiac ye-gluten uzwela: ekubeni uphando kulo mqathango lusebuncinaneni, akubona bonke oogqirha abawwamkele njengento "yinyani". Ngenxa yoko, akubona bonke abaza kubonelela izigulane ngokuxilongwa kwentswelo ye-gluten. Abo bagqirha abaza kuxilonga le meko baya kuhlola uvavanyo lwe-celiac kunye nokulawula i-celiac kuqala.
Sekunjalo, uphando olutshanje lwezokwelapha olunefuthe lobunene be-gluten luye lwaqinisa inkcazo yokuba yimeko ehlukile kwisifo se-celiac.
I-Celiac ibangelwa yimpendulo yomzimba wakho kwiprotheni ye gluten efunyenwe ngqolowa, i-hareyi kunye ne-rye.
Akucaci ukuba yiyiphi into ebangela ukuba u-sensiti-gluten-ngokwenene, inokuba yinto engekho gluten yengqolowa kunye nezinye izityalo ze-gluten (ezenza ukuba "ukukhathazeka kwengqolowa engekho yeliyo" igama elingcono). Nangona kunjalo, abaninzi abaphandi bezonyango bayaqhubeka bebhekisela kwimeko "njengengqondo engekho yeliliac gluten," okwangoku ngoku.
Ukuze ufumane umfanekiso ongcono weempawu eziqhelekileyo ezitholakala kwi-gluten sensitivity, ndathetha nabaphandi abathathu abagqithisileyo abaye bachitha ixesha elininzi befunda imeko: uDkt. Alessio Fasano, uDkt. Kenneth Fine, noDkt. Rodney Ford. Aba bathathu bathetha nam malunga namava abo ekliniki abandakanya izigulane ezinobuncwane be-gluten. Kufuneka kuqatshelwe ukuba kwezinye iimeko, izimvo zabo azizange ziqinisekiswe uphando olushicilelweyo okanye lwamkelwe luluntu jikelele.
Iimpawu zoBuncwane beGluten Ziquka iziMpawu ezininzi zokuGaya
Iimpawu zobuncwane be-gluten zivame kakhulu, ngokutsho koogqirha abaye baphando kwaye baphatha izigulane.
Umzekelo, uDkt. Fasano, ophethe i-Massachusetts General Centre yoCwaningo lweCeliac kwaye owanyathelisa iphepha lokuqala elichaza i-molecular for gluten sensitivity, uthi abantu abanomdla ngokugqithiseleyo bahlala bephethe "iimpawu ze-IBS", kubandakanywa uhudo kunye " isisu esibuhlungu." (Kakade, kukho ukugqithana okukhulu phakathi kweempawu zesifo seesilonda kunye neempawu zesifo se-celiac , kwakhona.)
UDkt Fine, owasungula i- Enterolab kunye nenkqubo yokuvavanya ukukhathazeka kwe-gluten , uthi abaninzi abantu abafumene ukuba ne-gluten uzwela "banezinye iimpawu ze-GI - nantoni na ekusukeni kwintliziyo ukuya ekuqotheni.
I-diarrhea yi-classic, kwaye ukukhupha i-classic, [kwaye] igesi edlula yinto eqhelekileyo. "
Iingxaki ze-Neurological Ingaba Yi-Gluten eVakalayo yokuBamkela Ubunono
Njengokuba kunjalo nesifo esiqhekezayo, ukukhathazeka kwe-gluten kunokubangela ukukhathala, inkohlakalo yengqondo kunye nezinye iingxaki ezinengqiqo, kubandakanywa nokugqithiswa kwe-gluten-ukungabikho kokuxhatshazwa kweengxaki , iiDr. Ifasano kunye neBango elihle.
UDkt. Fasano uthi ubona iintloko (kuquka i- gluten-incuted migraines ) kunye nenkohlakalo yengqondo malunga nengxenye yesithathu yabantu abaye bafumanisa ukuba unobunqunu obungabonakaliyo boluhlaza. Abantu abaxilongwa ngokuba ne-gluten uzwela nabo bavakalisa iimvakalelo ezibangelwa yi- gluten-depressed depression and anxiety, kwaye ngokwenene iziphumo zesifundo zixhasa imbono yokuba i- gluten inokukwenza uxinezeleke xa unobulunga kodwa ungenayo isifo se-celiac.
(Ukuxinezeleka kunye nokuxhalaba kuye kwaxhunyaniswa nesifo esiqhekezayo.)
UDkt. Rodney Ford, iChristchurch, isazi sezingane saseNew Zealand kunye nomlobi we -Gluten Syndrome , wayengowokuqala ukuxokisa ukuba ubuninzi be-gluten bubaluleke kakhulu kwiimeko ze - neurological . "Kucacile ukuba kunye ne-gluten, enye yezinto ezijoliswe kuyo ziyizicubu ze-neural," ushilo uDkt Ford.
Iimpawu zesikhumba, ukuphazamiseka kwe-endocrine, intlungu ehlangeneyo eqhelekileyo kwi-Gluten senensitive
I-Dermatitis herpetiformis (DH) yimeko yesikhumba ngokuqhelekileyo ihambelana nesifo se-celiac (ukuba une-herpetiformis isifo se-dermatitis, unesi sifo se-celiac ukuba unemiphumo emihle yokuhlolwa kwegazi ). Nangona kunjalo, abantu abanomdla wokutya bahlala bebonisa iintlobo ezahlukahlukeneyo kunye nezinye iimeko zesikhumba ezicacileyo xa zihamba zingenanto, ngokutsho kwamava ophando.
UDkt. Fasano uthi ubonakele uninzi lwesikhumba kubantu abanengqondo engeyiyo leliac gluten. Uyachaza: "Akuyiyo i-DH-yinto efana ne-eczema," kuchaza. Enyanisweni, kukho ubungqina bokuthi ukutya i-gluten-free inokunceda nge-eczema , nakubantu abangenayo isifo se-celiac.
Zombini iidrama. I-Ford kunye neFine bayavuma ukuba isikhumba sakho sinokubandezeleka xa unobulunga-gulen-sensitive, nge-rashes nezinye iimpawu zesikhumba. Iimpawu ziyanyamalala xa umntu elandela ukutya okubangelwa i-gluten kwaye aphinde abuyele kwimeko yokuhlutha .
Njengesi sifo se-celiac, ububele bendalo bubangelwa iimpawu ezibandakanya inkqubo yakho ye-endocrine, njengokungabikho kwengqondo kunye nesifo se-thyroid , uDkt Fine uthi. Kwakhona ubona i- gluten-eyabangela i-asthma kwabanye abantu abane-gluten sensitivity. Ukongeza, iiDrk. Enhle, uFasano kunye neFord bonke baqaphele ukuba abantu abaninzi banesifo semvelo, ubuhlungu obudibeneyo kunye nokugubungela / ukuphazamiseka kwimida yabo ekungeneni kwe-gluten. Zomibini nazo ziyimpawu eziqhelekileyo zesifo se-celiac.
Uphando kwi-Gluten Sensitivity Symptoms Oqhubekayo
Ngokuqinisekileyo, ukuqaphela ukukhathazeka kwe-gluten njengemeko eyahlukileyo eyahlukeneyo ukusuka kwisifo se-ecliac kunye nesifo sengqondo sesifo esilumkileyo sisisandul 'ukutsha, kwaye akukho luphando olunzulu lokudibanisa naziphi na iimpawu ezikhankanywe ngentla ngokugqithiseleyo ekuveleni uveliso (nangona uvavanyo lokudandatheka alukabi ku phendulwa). Amagqirha amaninzi ahlawula iingxelo ze-non-celiac gulen sensitivity, kwaye aya kuthi izigulane zabo ukuba abanalo ingxaki kunye ne-gluten ukuba bavavanya ingxaki yesifo esiqwengileyo.
Akukho nto ichaza ukuba kutheni iimpawu zentsholongwane ye-gluten kunye nesifo se-celiac zivakaliswa ngokuchanekileyo. Nangona kunjalo, uDkt Ford unenkolelo: Ukholelwa ukuba iimpawu ze-gluten uzwela kunye nezifo ze-celiac ziyafana ngokuba i-gluten ibangela impawu ngqo kwiibini zombini, kwaye loo monakalo emathunjini awudlala indima ebalulekileyo ekubangela iimpawu.
Ngamanye amazwi, nangona i-celiacs ifumana i -atrophy ekhohlakeleyo kunye nabantu abanomdla wokutya, abanakho ukukholelwa ukuba amaqela omabini athola impawu ezithe ngqo kwi-gluten engahambelani nomonakalo emathunjini.
"I-atrophy engummangaliso iyilingo lokuxilongwa kwezicubu ze-celiac, kodwa ayinakunxulumene neempawu ozifumanayo xa udla i-gluten," kusho uDkt. Ford. "Ukukhathazeka kweGluten kubaluleke kakhulu isifo se-neurologic. Iimpawu zesisu zibangelwa yinkcenkceshe kwinkqubo ye-nervous system-leyo yindlela yokuzibandakanya eyenza intliziyo yakho, imiphunga kunye nesisu. "U
Akukho nanye kule nkcazelo malunga neempawu ezingabonakaliyo ze-gluten iimpawu ezibonakaliswe kwizifundo zeklinikhi njengoko kunjalo; ngeli xesha, limelela nje iingcamango zamagqirha abaphanda ngesihloko. Nangona kunjalo, njengoko uphando luqhubeka, siya kuqiniseka ukuba sifunde ngakumbi malunga nale mpawu kwaye ngubani na onokuyithintela.
Imithombo:
Biesiekierski J et al. Iinjongo zeGluten Iimpawu zoBuncwane kwiZifundo ezingekho phantsi kwezifo ezi-Celiac: I-Trial-Blind i-Randomized Trial-Controled Trial. I-American Journal yeGastroenterology. Ishicilelwe kwi-intanethi ngoJan. 11, 2011. i-doi: 10.1038 / ajg.2010.487.
Elli L et al. Ubu bungqina boBukhona be-Non-Celiac Ubutyebi bobubele kwizigulane ezineMpawu zoMzimba ezisisisombululo: Iziphumo ezivela kwi-Gluten Challenge. Amanzi . 2016 Feb 8; 8 (2). pii: E84.
Fasano A et al. Ukutshatyalaliswa kwamathambo okubonakalayo kunye ne-mucosal gene gene expression) kwiimeko ezimbini ezinxulumene ne-gluten: isifo se-celiac kunye nobutyebi be-gluten. I-BMC Medicine 2011, 9:23. i-doi: 10.1186 / 1741-7015-9-23.
Fasano A et al. Isibuko seengxaki ezinxulumene ne-gluten: ukuvumelana malunga nokutyunjwa kwamagama omtsha kunye nokuhlelwa. BMC Medicine . I-BMC Medicine 2012, 10:13 i-doi: 10.1186 / 1741-7015-10-13.
Uhde M et al. Ukulimala kwamathambo emathunjini kunye nokusebenza komzimba ngokusesikweni kuBantu abaBikayo ukuBonakala kwiBanga ngokungabikho kwezifo zeCeliac. Gut . 2016. Ithenda: 10.1136 / gutjnl-2016-311964.