Yintoni eyenza ukuba i-Gluten 'Sensitivity'?

Akucaci nokuba ingaba i-gluten ibangela ubumnene bendalo

Xa uthetha malunga nempilo yempilo yokuba abaninzi beekliniki ngoku zibiza ngokuthi " ukungahloniphi kwe-gluten ," kulula ukugxininisa kwiprotheni ye gluten . Emva koko, i-gluten ekhokelela kumonakalo wamathumbu emzimbeni we-celiac , kwaye ngoko ayizange ibonakale njengoluhlu olukhulu, xa le meko entsha yachazwa kuqala, ukucinga ukuba i-gluten ibangelwa yimpawu apha, ngokunjalo.

Kodwa kuthekani ukuba i-culprit ebangela ukuba iimpawu ze-"gluten sensitivity" azigcini? Kuthiwani ukuba, endaweni yoko, ingenye enye imveliso-okanye i-compounds multiple - efumanekayo kwi-gluten eneengqolowa zengqolowa, ibhalley, neer rye, mhlawumbi nakwezinye ukutya, na?

Le ngcamango eyokuqwalasela. Izixhobo ezinokuthi zifumaneke zifumaneke kulawo manqila ziquka i-fructans (i-carbohydrate eyinkimbinkimbi engabangela iimpawu kubantu abaneentsholongwane zesifo sengqondo) kunye ne-amylase trypsin inhibitors (eziyi-protein), ngaphezu kweprotheni gluten.

Nantsi oko uphando lubonisa kuzo zonke iziqulatho ezintathu zokutya, kunye nokuba zinokuthintana njani novelwano lwengqondo olungenalo celiac.

I-Gluten Ngaba yiNkokeli ePhambili

Le ngqolowa yenkalo apho abantu abaninzi bajolise khona. I-Gluten yiprotheni enokusetyenziswa kwezityalo ukugcina izondlo kwisizukulwana esilandelayo sesityalo. Itholakala kwimbewu yezityalo eziziinkozo - inxalenye yesityalo esicinga ngayo, kwaye siyisebenzise, ​​njengokutya.

Uphando lokuqala olwenziwe kwi-non-celiac gulen senitivity, eyapapashwa ngo-2011, i-gluten ene-fingered njengengxaki kwimeko esanda kuchazwa. Olu phofu luthi i-gluten yenza ukuba amathambo abantu avuke kwaye avuke ngaphandle kokubangela isifo se-celiac. Abaphandi baqukumbela laba bantu basabela kwi-gluten kwizidlo abazidlayo.

Ukususela kuhlolisiso lokuqala, kukho izifundo ezininzi ezisebenzise i-wheat gluten ecocekileyo ukuzama nokunyusa iimpawu kubantu abakholelwa ukuba babecala. Ezi ziphumo ezidibeneyo.

Isifundo esisodwa, umzekelo, wasusa zonke izityalo zokutya okusanhlamvu ezisuka kwiziqhamo zezifundo ezingama-37, waza wabondla ngengqolowa egqibeleleyo yengqolowa (izifundo zazingayazi xa zidla i-gluten kwaye zidla i-placebo). Abantu abafundayo abazange bafumane iimpawu zokutya xa besidla i-gluten ecocekileyo, kodwa abanye babo bafumana ukuxinezeleka .

Olunye uphando lusetyenzise inkqubo efanayo ukuba "inselele" abantu abathi baxhamla-gluten kwaye bafumanisa ukuba abanye babo baphendule kwi-gluten ecocekileyo. Kulo pho nonongo, abantu abayi-101 bathi iimpawu zabo zokugaya ukutya ziphuculwe xa zilandela ukutya okubangelwa i-gluten, kwaye i-14% yazo yabonakala yimbi xa ingazi kakuhle i-gluten njengenxalenye yesifundo.

Umgca ophezulu: Abanye abantu abathi banengqondo kwi-graut gluten kubonakala bephendula kwi-gluten, kodwa abanye abaninzi abazange basabele xa bondla i-gluten egciniweyo engazi. Uphando olongezelelweyo olu lufunekayo.

I-FODMAPs Ingxaki kwi-IBS

Kungenzeka ukuba ingxaki ngqolowa iifructans zayo. Yiyiphi enye yezifundo zakutshanje kwi-gluten sensitivity - enye nabantu abangama-37 abangazange bafumane iimpawu zokugaya ukutya kwi-gluten ecocekileyo.

I-Fructans yi-carbohydrate eyinkimbinkimbi eyenza intliziyo yakho emathunjini, enokubangela i-gesi, ukubhubhisa, ukuchithwa, intlungu, isifo sohudo kunye nokuqhaqha. Olu luhlobo oluthile luhlolwe i-FODMAP (i-fermentable, i-oligo-, di-, i-monosaccharides kunye ne-polyols), iishukela ezifunyenwe ngqolowa kunye nokutya okunye xa abantu abafundayo bengazange babone iimpawu zabo zamathumbu zibe zibi kakhulu kwi-gluten ecocekileyo.

Umgca wezantsi: I-FODMAP ibonakala ibangela iimpawu zokugaya inyama kubantu abaninzi abaneengxaki zesifo seesilonda, kunye nokutya okuphantsi kwe-FODMAP kubonakaliswe ukunciphisa iimpawu malunga neekota ezintathu zalabo abane-IBS.

Kodwa akude kucacise ukuba ingxaki kwi-"gluten sensitivity" yinyani ye-FODMAP, kwaye nokuba isisombululo sisidlo se-FODMAP esincinane, kunokutya okungekho gulen. Kwakhona, uphando oluthe lufunekayo.

I-Amylase i-Trypsin Inhibitors Ngaba ngabaqhubi be-Inflammation

Kukho isahlulo sesithathu samanqwanqwa enjenge-gluten anje esaziwayo njengengxaki: i-amylase trypsin inhibitors. Ezi proteins ngokwenene zendalo zephilisi zendalo - zenziwe yityalo ukuze zikhusele kwiinambuzane.

I-Amylase trypsin inhibitors kwimbewu ye-gluten ngokwenene yenza ukuba kunzima okanye akunakwenzeka ukuba izimbungulu zigubungele i-kernel yenqolowa. Iingqolowa zanamhlanje ziye zazala ukuba zininzi ezininzi zeeprotheni.

Ingxaki, i-amylase trypsin inhibitors ngqolowa (kwaye mhlawumbi nezinye izityalo ze-gluten) zibonakala zibangela ukuvuvukala kwabanye abantu, zombini emathunjini nakwezinye izidumbu zabo. Abaphandi bafunda ezi proteins baqikelela ukuba banokudlala indima kwisifo se-celiac, kwi-non-celiac gulen sensitivity, kwaye mhlawumbi kwezinye iimeko eziqhutywa yi-inflammation.

Umgca ophantsi: Ama-Amylase trypsin inhibitors angenza inxaxheba okanye enze nokuba abantu bathini ukungahloniphi kwe-gluten. Nangona kunjalo, okwangoku bancinci ukufunda ngezi zizathu ezintathu.

Yiyiphi na?

Akukho ndawo esicacileyo okwangoku ngoku kunokubangela ukuba imeko esiyibiza ngokuthi "ukungahloniphi kwe-gluten sensitivity". Ingabangela ukuba i-gluten, i-FODMAP, i-amylase trypsin inhibitors, enye inhlanganisela yezinto ezintathu, okanye enye into epheleleyo.

Ukuba i-gluten ayinaso ityala kodwa enye into kwi-gluten isinhlamvu, ke abantu abanokuba nemeko bangadinga ukulandela ukutya okukhululekile kuzo zonke iinxalenye zengqolowa, ierley, neer rye ... kungekhona nje i-gluten.

Uphando malunga neminyaka emininzi ezayo kufuneka kusitshele ngakumbi malunga nezinto ezibangela ukuba uvelwano olungenanto lwaloo-gluten kunye nabangaphi abantu abanalo. Oko ke, kufuneka kusincede siqonde indlela yokuyixilonga nokuyiphatha ngayo.

Imithombo:

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Biesiekierski J et al. Akukho miphumo ye-gluten kwizigulane ezinokwenziwa kwengqondo engekho-celiac yoluttensibility emva kokunciphisa kokutya okunokutsha, okwenziwe ngokukhawulezileyo, okwi-carbohydrate emfutshane. Gastroenterology . Ngo-Agasti wama-2013; 145 (2): 320-8.e1-3.

Biesiekierski J et al. Ubuninzi be-gluten uzwela: ukuhlaziya idijithali ndawonye. I-European Union Gastroenterology Journal . 2015 Ngo-Apr; 3 (2): 160-5.

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Fasano A. et. al. Isibuko seengxaki ezinxulumene ne-gluten: ukuvumelana malunga nokutyunjwa kwamagama omtsha kunye nokuhlelwa. BMC Medicine. I-BMC Medicine 2012, 10:13 i-doi: 10.1186 / 1741-7015-10-13. Ishicilelwe: 7 Februwari 2012

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