Oko Siyamazi Ngayo
Usayiva ukuba isifo esingapheliyo sisifo ( ME / CFS ) "sisifo esiyimfihlakalo," kodwa uhlobo kunye nezixhobo zesifo ziqala ukuma, ngenxa yemigudu eqhubekayo yabaphandi. Kule minyaka, ingakumbi yakutshanje, sifunde imali enkulu. Olunye ololo lwazi lubonisa iindima ezivuthayo kunye nokuzimela komzimba kungadlala kule sigulo.
Ukuqonda uphando, kunceda ukwazi okufutshane malunga neenkqubo ngokwabo.
Ukuvuvukala: Uncedo kwaye unobungozi
Sonke siyazi ukuba ukuvuvukala kubandakanyeka kwizifo ezininzi kunye nokulimala, kwaye akunqabile ukufumana indlu engenayo ubuncinane isicatshulwa esisigxina . Siqhwaqisa kwaye sikhulisa ukulimala kwethu, ukubenza bangabikho.
Nangona kunjalo, unokumangaliswa ukuba ufunde ukuvuvukala inxalenye yempendulo enempilo kwiingxaki zomzimba. Xa inkqubo yakho ibona ingxaki-ingaba iyintsholongwane okanye ibhaktheriya, okanye izicubu ezonakaliswe ukulimala-kubangela ukuphendula okuvuthayo.
Yintoni eyenzekayo kukuba imilambo yegazi iyancipha ukuze ifumane igazi elingakumbi kwindawo leyo, kunye neprotheni eyongezelelweyo igxothwa kuloo gazi. Iigazi zegazi ezimhlophe zihamba ukusuka emithanjeni yegazi zibe kwindawo yengxaki kwaye zibulale okanye zihlambulule nantoni na engafanele ibe khona. Emva koko izicubu ziqala ukuphilisa.
Ngoko xa ushitshisa i-shin yakho okanye uphazamise isangqa, ukuvuvukala okuncinci into enhle.
Kuthetha ukuba inkqubo yokuphilisa isebenza.
Ngakolunye uhlangothi, xa ukuvuvukala kungapheli ngenxa yomonakalo oqhubekayo okanye isistim somzimba sokungasebenzi, ke unenkinga.
Umzekelo womonakalo oqhubekayo unokuba yinto enjengeentlungu zasemva kwenzakalo eyenziwa yimeko engafanelekanga, okanye umonakalo ophindaphindiweyo ngenxa yezifo.
I-immune system system ingakwazi ukuthetha ngokuzenzekelayo.
Ukuzimela ngokuzenzekelayo: I-System Misfires
Ngokuzimela, umzimba uphantsi komlilo onobungane. I-immune system iye yafika e-haywire kwaye ngoku ichonga inxalenye yomzimba wakho njengomhlaseli wamanye amazwe. Emva koko kubangela inkqubo yokuvutha kwaye ithumela kwiiseli ezizodwa ukutshabalalisa ithagethi kwaye iqalise inkqubo yokuphilisa.
Kuphela ngoku, inkqubo yokuphulukisa ibangela ngaphezulu kwanoma yintoni inxalenye yomzimba isistim somzimba sakho asiyithandi, ngoko inkqubo iyaqhubeka ngokungapheliyo.
Kubalulekile ukuba uqaphele ukuba akuyiyo yonke into eyenziwa yintsholongwane yomzimba.
ME / CFS: Yintoni esiyaziyo?
Abaphandi baye bade bakholelwa ukuba i-ME / CFS ibandakanyeka ukuvuvukala okungapheliyo. Izifundo zityhila iindawo ezininzi zokuvuvukala kunye nokuphendula okukhuselweyo kwe-immune kwigazi lezigulane ze-ME / CFS. Abanye abaphandi ngoku bajonga i-ME / CFS ukuba ibe yi-neuroimmune okanye i-neuroendocrineimmune.
Nangona kunjalo, sisafunda ngendima ethile yokuvuvukala kwimeko. Uphando olutsha lubonisa umfanekiso okhulayo wokuzimela. Kwaye xa kubandakanyeka ukuzibandakanya, umbuzo omkhulu: yintoni ekujoliswe kuyo?
Izizathu ezinokwenzeka zokuvuvukala
Uninzi lwengingqi ye-ME / CFS yophando ithatha ukuvuvukala njengoko kunikwe. Ngenye igama elithi myalgic encephalitis (ME), eliye lamkelwa ngabaphandi abathile, i-encephalitis ithetha ukuvuvukala kwengqondo kunye nentambo yomthambo.
Abanye abaphengululi bathi kukho okubangela ukuvuvukala okungabandakanyi ukuzimela.
Uvavanyo olwenziwe ngo-2012 oluzama ukuhlukana nokukhathala okungapheliyo, isifo esingapheliyo sokugula, kunye ne-encephalitis yamagqabini kwiindidi ezahlukileyo zifumene ukuba izigulane ze-ME zinamanqanaba aphakamileyo e- cytokines interleukin-1 kunye ne-tumor necrosis i-alpha kunye ne-neopterin, umsebenzi wokuzivikela ngomzimba.
Ngoku kutshanje, uphando lubonisile ukuba abamakishi abanobukrakra abanokuchonga ngokucacileyo le meko kwixinzelelo okanye ukuziphatha kwezifo.
Uphando olupapashwe kwi- Metabolic Brain Disease linye nje lombutho okhulayo ocinga ngokuxinzeleleka kwe-oxidative kunye ne-nitrosative (O & NS) kunye namanqanaba aphantsi okulwa ne-antioxidant indlela engenzeka ngayo ye-ME / CFS, ethi le miba ingakhokelela kwi-pathology ye-immuno-inflammatory pathology.
(Funda kabanzi malunga nale ngongoma: Uxinzelelo lwe-Oxidative kunye nePall Protocol .)
Abanye abaphandi bacebise ukuba ezinye izifo ezinokuthi zingabonakali, zingabangela ukusetyenziswa kwamagciwane okungapheliyo, okuza kubangela ukuvuvukala okungapheliyo kunye nokunyuka kweengxaki. Omnye wabakrokreli abakhulu kule meko yi- Epstein-Barr virus , eyenza i-mononucleosis ("isifo sokubanga.")
Iimpawu zokuphenya ze-retrovirus zango-2013 kwisigalo esisekelwe kumathambo esekelwe kwimfundiso yokuba, ngokuxhumeka kwengqondo, isifo se-gut can lead to inflammation of the brain. Abaphandi bafumene ubungqina, kodwa le nto yayincinci, isifundo sokuqala kunye nomsebenzi omningi omele uyenze kule ndawo.
I-Case for Autoimmunity
Abanye abaphandi bafumene ubungqina obubonisa ukuba i-ME / CFS, ubuncinane kwinqanaba, isifo esingenasistim. Kuye kwaphakanyiswa iithagethi ezimbalwa ezihlukeneyo zesistim somzimba.
Ngophando luka-2013 oluhlolisisa ubudlelwane obunokwenzeka be-O & NS kunye nokuzimela, abaphandi bathi ubukho bama-cytokines angaphangeliyo kunye nezinye izidakamizwa eziyaziwayo ezinxulumene ne-ME / CFS zinokubangela ukuba zilandele. Oko kuthetha ukuba umsebenzi wokuzimela ungabangela umqathango kunokuba ubangele isizathu. Aba baphandi bacinga ukuba ukusuleleka kwiintsholongwane zentsholongwane kungakhokelela kwiinkqubo ezimbalwa ezingabangela ukuba umntu asebenze ngokufanayo: usebenze ngokumelana kunye nokulinganisa i-molecule.
Kwiimpawu zemileksi, i-immune system ilwa ne-agent esebenzayo kwaye iqala ukudibanisa kunye nesisele efanayo emzimbeni kwaye ngoko iqala ukuhlasela. Okubalulekileyo, kuba zombini iiseli zibukeka njengodada, isimiso somzimba sokuzikhusela sisibonakalisa zombini amadada, xa eqinisweni enye i-goose, kwaye i-goose ikhona kwizinto eziphilayo.
Ekusebenziseni ukukhanya, umzimba uhlaselwa yintsholongwane, isistim somzimba siphendula ngokusebenzisa iiseli ezikhethekileyo, kwaye ngenxa yesizathu esithile, ukuba i-activation ihoxise uhlobo oluthile lweseli ekhethekileyo-isistim esisodwa-esiqala ukuhlasela izicubu zomzimba.
Kwisifundo esifanayo, abaphandi bacwangcisa ezinye iindlela eziliqela apho i-ME / CFS inokubangela ukuzenzekelayo, kuquka ukungasebenzi kwemithachondria, enika amandla kumaseli akho, kunye nomonakalo wamaselula obangelwa yi-O & NS eyenza ukuba isimiso somzimba wakho sokuzivikela singabonakali.
Ucwaningo oluthile luka-2013 olubandakanya abaninzi abaphandi abafanayo libeka ithuba lokuphendula ngokuzenzekelayo kwi-5-HT, eyaziwa ngokuba yi- serotonin . Njenge-hormone kunye neurotransmitter, i-serotonin yenza imisebenzi emininzi ebalulekileyo kumathambo kunye nengqondo. I-Serotonin dysregulation sele ikholelwa ukuba ibandakanyeka kwi-ME / CFS.
Abaphandi bathi bangaphezu kwama-60 ekhulwini kwabathathi-nxaxheba nge-ME / CFS abavavanywe kakuhle kwi-auto-activity activity against 5-HT-ngaphezulu kwamaxesha angama-10 kwinqanaba leqela lokulawula, kunye ne-quadruple izinga lalabo abanexhala elide elingapheliyo ukuhlangabezana ne-criteria ye-ME / CFS.
Ngaba Izimpendulo Ezininzi Zingaba Zikulungile?
Ekugqibeleni, kungenzeka ukuba iimeko ezifaniyo ze-ME / CFS zinemibangela eyahlukileyo yokuvuvukala, kwaye ezinye iimeko zizenzekelayo xa ezinye zingekho. Khumbula ukuba i-ME / CFS ingahluka ngokuthe ngqo kumntu omnye komnye. Kungenzeka ukuba amaqela amaninzi ahlukeneyo, kwaye mhlawumbi izifo ezahlukileyo, ngoku zifakwe kwidiksi enye.
Iingcali zenzululwazi zisasebenza ukuyihlunga yonke into. Okwangoku, kufuneka ufumane iindlela zokulawula imeko yakho. Kubalulekile ukuba usebenze kunye nogqirha wakho ukujonga uhlobo lwenkcazo yakho ye-ME / CFS kunye nendlela engcono yokuyiphatha ngayo.
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