Kuyinto engafanelekanga ukubiza i- HPV "intsholongwane yomhlaza wesibeleko". Kuye kwaziwa ngeminyaka ukuba i- papillomavirus yabantu ayihlanganiswa kuphela nemilwane yomzimba kunye nomhlaza wesibeleko , kodwa kunye nezinye iidrama ezibandakanya umhlaza wesibeleko , umhlaza wesi-penile , nomhlaza wesifo.
Kwiminyaka yakutshanje, ke, izazinzulu ziye zafumana ubudlelwane obuqinileyo nomhlaza womlomo , ngokukodwa-ngokukodwa ezinomdlavuza emlonyeni nasemqaleni.
Ezinye izazinzulu ziye zatshengisa ukuba, ngowe-2020, ezi ngqamana zingaphinde zithathe indawo yomhlaza wesibeleko njengomhlaza oqhelekileyo obangelwa yi-HPV.
I-HPV Infection njengengxaki yengozi
Nangona, ehlabathini lonke, amaninzi emilonyeni kunye nomlomo we-throat isasetyenziswa kunye nokusetyenziswa kwecuba kunye / okanye utywala, uphando luye lwaqala ukubonisa ukuba i-HPV inokuba yinto enye inkulu yengozi. I-HPV ibonakala ixhamle ngokukodwa nomhlaza weetoni, nangona ifunyenwe kwiisampuli ze-biopsy ukusuka kwezinye iisayithi ezikufuphi.
Ngokungafani nomdlavuza womlomo wesibeleko, kukho nezinye izinto ezinobungozi kumdlavuza womlomo nasemqaleni. Ezi ngozi ziquka utywala kunye nokusetyenziswa kwecuba .
Uphando oluphandwe ngo-Oktobha 2011 lufumene ukuba iziganeko zee-cancer ze-HPV ezinxulumene ne-throat ziye zaphindwa kabini kwi-US kwiminyaka phakathi ko-1980 no-2004. Ngaphezu koko, ipesenteji zomhlaza zomlomo nezomlomo ezabangelwa yi-HPV zakhula ngokukhawuleza, njengoko inani le-khancer-related related-cancer liye lancipha kwixesha elifanayo le-20+.
Sexual Oral and Oral Cancer
Ingxaki yesifo esinikizwa ngesondo iphela njani ehambelana neekhensi ezikude kude nezitho zangasese? Impendulo mhlawumbi ngesondo ngomlomo. Izifundo eziliqela zibonise ubudlelwane phakathi kwesondo lomlomo kunye nobukho be-HPV DNA emasimini omlomo nasemqaleni. Ezinye izifundo zibonise ubudlelwane phakathi kwesondo lomlomo kunye ne- HPV-positive cancer cancer , ikakhulukazi kulabo bantu benza isondo ngomlomo kubantu.
Kuthatyathwa njengeqela, ezi zifundo ziyakhusela esinye isikhumbuzo sokuthi isondo somlomo akusilo isondo esilondekileyo . Izifo ezahlukahlukeneyo zesondo ezithandana ngesondo nazo zingasasazeka ngesondo ngomlomo , kuquka i- herpes , i-gonorrhea, i- chlamydia kunye ne- syphilis . Izisombululo zesondo ezikhuselekileyo kufuneka, ngoko, zisetyenziselwe ubulili bomlomo kunye nobulili besini nesondo . Oku kunjalo ngokukodwa kubantu abaneentlobo zesisu zomzimba okanye iintsholongwane zikaGawulayo ekubeni zombini iintsholongwane ziye zaboniswa ukuba zibeke abantu ithuba lokufumana i-HPV.
Ingxaki nge-HPV Testing
Iingcali zenzululwazi ziye zabuza indima yeemvavanyo ezahlukeneyo ze-HPV ekuqikelelweni kwezigulane kwiindawo ezahlukeneyo. I-HPV ayiyintsholongwane elula yokuvavanya. Ukufumana nje i-HPV DNA kwiisampuli ukusuka kwi-swab yomlomo akuthethi ukuba abantu baya kuba nomhlaza.
Ngapha koko, abaninzi abantu abane-HPV-positive test ye-biopsy test negative not for HPV DNA kuphela kwiiseli zemilomo yabo kodwa ne-anti-HPV antibodies egazini labo. Ngokubanzi, ngoko kunzima kakhulu ukuchaza intsingiselo yokuvavanya , okanye ukungalunganga, vavanyo lwe-HPV .
Umyalezo weKhaya lokuThatha kwi-HPV kunye ne-Oral Cancer
- I-HPV, kwaye ngokukodwa i-HPV 16, ibonakala ibamba indima ekuphuhliseni inani elininzi lomdlavuza emlonyeni nasemqaleni.
- Ukulala ngesondo kunomngcipheko wokufumana usulelo lwe-HPV emlonyeni wakho okanye emqaleni.
- Ekubeni ininzi ye-HPV-ehambisana nomdlavuza we- throat ibonakala ibangelwa yi- HPV 16 , kunokwenzeka ukuba ukugonya kwe- HPV kunokuba luncedo ekukhuseleni.
- Nangona iziphumo zokufunda zidibeneyo, kubonakala ngathi ukutshaya nokusetyenziswa kotywala kunokunxibelelana nokusuleleka kwe-HPV ukunyusa umngcipheko womdlavuza .
Imithombo:
Begum et al. (2005) "Ukusasazwa kweTisue ye-Papillomavirus yabantu 16 I-DNA Integrationin Izigulane ngeTonsillar Carcinoma" I-Cancer Res 11 (16): 5694-9
Chaturvedi et al. (2011) "I-Papillomavirus yabantu kunye ne-Oropharyngeal Cancer Incidence eMelika" I-JCO Oct 3, 2011:; ipapashwe kwi-intanethi ngo-Oktobha 3, 2011
U-D'Souza et al (2007) "Uvavanyo lwe-Case-Control of Human Papillomavirus kunye ne-Oropharyngeal Cancer" NJEM 356: 1944-56.
Hererro et al. (2003) "I-Papillomavirus yabantu kunye ne-Canal Canal: I-Arhente yamazwe ngamazwe okuPhando kwiCancer Multicenter Study" J. J. Natl Cancer Inst 95 (23): 1772-83
Kreimer et al. (2004) "Ukwahlukana kobulili kwi-Biomarkers kunye neentlupheko ezinxulumene nePapilomavirus ye-Human-16, -18, no -33." -U-Seroprevalence "iTrans Trans Dis, V31 (4): 247-256
Kreimer et al. (2004) "Ulwaphulo lwe-Papillomavirus lwe-Human Oral Human in Adulthood ludibanisene nokuziphatha ngokwesondo kunye ne-HIV Serostatus." JID 189: 686-98