Ukuhlamba ngokuqhelekileyo kuvela kwi-duodenum okanye kwisisu, kodwa kunokuhlakulela kumathumbu amakhulu. Nangona iimpawu zokulumkisa zihlala zikhona, ezinjengezitho zomzimba okanye izigulane ezimnyama / ezimnyama, ezinye izigulane-ingakumbi asebekhulile-zingenaso isilumkiso ngaphambi kokuba zihlaziye.
Ukongeza kwimidala yobudala, ezinye izinto ezinobungozi kule nkalo ziquka ukusetyenziswa kwe-NSAID ezininzi (umzekelo, ibuprofen ngaphezu kwe-counter ibuprofen edibene ne-NSAID yesigxina), igazi elincinci njenge-aspirin okanye i-coumadin (igazi elincinci), i- corticosteroids , ukutshaya, ukusetyenziswa kotywala kakhulu , kunye nembali yangaphambili yezilonda zesisu kunye nokuphuma kwamagciwane . Ukongezelela, ezinye izigulana ziye zavezwa kwiibhaktheriya H. pylori ngexesha elithile ebomini babo. Le bhaktheriya eqhelekileyo idibene nomngcipheko ophezulu wezilonda zamachiza.
Ngethamsanqa, ngenxa yezi gulane ezifuna ukuthatha i-NSAID ukunyanga i-arthritis, zikhona iindlela zokunciphisa ingozi yezilonda kunye neengxaki ezivela kwizilonda ezifana nokuphuma kwamagciwane. Sacela uScott J. Zashin, MD (i-rheumatologist) kwaye wacetyiswa ezi ndlela ezili-9 zokunciphisa umngcipheko wezilonda zamachiza ezisuka kwi-NSAIDS.
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Sebenzisa i-Amafutha njengenye indlela eya kwi-NSAID yomlomoCinga ngezinye iintlungu ezinjengeTylenol okanye tramadol . Kukho neengonyango zonyango kwiintlungu zendawo ezibandakanya:
- Iifometha zeThermacare (ubushushu obumanzi)
- ioli efana neBenGay
- igalelo ye-NSAID gels okanye ii-patches usebenzisa i-diclofenac (i- Voltaren gel )
Ngoxa i-diclofenac yi-NSAID, isicelo sendawo singanciphisa izinga le-NSAID egazini kwaye linciphisa umngcipheko wokukhupha.
I-NSAID zomlomo zingaphakanyiswa okokuqala. Kukho enye indlela yokuphucula ngokuphumelelayo intlungu, ngaphandle kokubangelwa yimiphumo emibi.
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Lungisa Isisombululo Sakho Ukunciphisa Ingozi Yemiphumo YecalaKukulungele ukuthatha umlinganiselo ophantsi kakhulu we-NSAID eyimfuneko ukukhupha iimpawu zakho. Ngokunciphisa umlinganiselo kwiqondo eliphantsi kakhulu, uyanciphisa umngcipheko weempembelelo.
Esinye isiphakamiso sokuba uqwalasele-kunye nogqirha-kuvunywa kwakho-kukuthatha i-NSAID yakho njengoko kuyimfuneko ngokuchasene nayo yonke imihla. Ngokwenza njalo, uya kunciphisa umngcipheko wemiphumo emibi.
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Thatha i-Dose Safe ye-NSAIDKulula nje: Gwema ukuthatha i-NSAID engaphezulu kweyodwa. Oku kungathi ngathi isicatshulwa esicacileyo kodwa ezinye izigulana zingathatha ezimbini ngenxa yokuncedwa kwentlungu. Basenokungaziqondi zombini iziyobisi (umzekelo, i-NSAID kunye ne-NSAID yesigxina). Ukuthatha ii-NSAID ezimbini ezahlukeneyo kuyingozi-kunokunyusa umngcipheko wemiphumo engathandekiyo kunye neziganeko ezingathandekiyo.
Thatha amayeza akho njengoko ulandisiweyo. Ukuba unemibuzo, unganqikazi ukubuza ugqirha wakho okanye umasipala.
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Amacwecwe aseCelebrex anciphisa ingozi ye-UlcerKufuneka uqikelele ukhetha i-NSAID, njenge-salsalate, enokuthi inomngcipheko ongencibiliko wokuphuma kwezilwanyana ngokuthelekiswa namanye ama-NSAID. Kwakhona, i-diclofenac, i-etodolac, i- meloxicam , kunye ne- Celebrex yi-NSAID ezinokuba neyona mngcipheko wezilonda.
Kukho idatha ethile yokufunda ebonisa ukuba iCelebrex inokunciphisa umngcipheko wokuphuma kumathumbu amakhulu. Thetha ugqirha wakho ukuze ubone ukuba i-Celebrex iyakuba yinto enhle kuwe. Musa ukulibala, i-Celebrex iboshwe, kwinqanaba elithile, ukukhupha ingozi. Ingozi yokulinganisela kunye neenzuzo.
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Proton Pump Inhibitors Ukunciphisa Ingozi ye-UlcerUkudibanisa iNSAID kunye neproton pump inhibitor (PPI) kunokunciphisa ingozi yesisu okanye isilonda esiswini. Oku kubalulekile kwizigulane kwingozi engakumbi. I-PPI iquka iProlosec (ekhoyo kwi-counter-counter), i-Aciphex, i-Prevacid, i-Protonix ne-Nexium. Kukho nemveliso edibanisa i-naproxen kunye ne-Prevacid kwimveliso enye.
Ngokumalunga nePPI, i-misoprostol (i-Cytotec) inokunciphisa umngcipheko wesilonda. Le mveliso kufuneka ithathwe amaxesha ama-4 / imini kunye nokutya ukufezekisa ukhuseleko oluphezulu, kodwa ukhuseleko oluthile lwenzeka xa kuthathwa kabini imihla ngemihla. Le mveliso iyafumaneka ngokudibanisa ne-diclofenac. I-Misoprostol kunye ne-diclofenac ithengiswa njengeArthrotec . I-Misoprostol iyaphikisana nabasetyhini abakhulelweyo okanye abanokukhulelwa kuba kunokubangela ukuphuma kwesisu.
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Ungayigcini iMpawu zoNyangoShedyuli rhoqo ukubonisana nodokotela wakho ukuba ahambe ngaphaya naziphi na iimpawu onokuzenza. Yenza umsebenzi wakho wegazi uhlolwe kuyo nayiphi na imiqondiso yokuphapha. Ukuba uthatha ii-NSAID, oku kufuneka kube yinxalenye yokulandelelana kwakho rhoqo nogqirha wakho.
Ngokusebenza, kunokwenzeka ukubamba iimpawu kwangaphambili kwaye uphephe imeko engxamisekileyo. Ekubeni i-NSAID ziyazi ingozi, zombini isigulane kunye nodokotela kufuneka afune iimpawu zokuphapha.
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Hlola u-H. PyloriCinga ukuvavanywa, kwaye ukuba kulungile, uphathwe nge-H. pylori bhakteria ukunciphisa umngcipheko wokuhlalisa isilonda. H. pylori (okuboniswe ngasentla) unokunyuka kwisisu okanye inxalenye yokuqala yesisu sakho esincinci kwaye uye wadibana nomngcipheko ophezulu wezilonda.
Enyanisweni, u-H. pylori usulelo luyimbangela eqhelekileyo yezilonda zesisu, kwaye kubangelwa ukuvuvukala kwesisu esiswini.
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Thatha ii-NSAID kwisisu esigcweleAkuqhelekanga kwizigulane ezithatha ii-NSAID ukuphuhlisa iimpawu zesisu. Ukuthatha amayeza kwisisu esipheleleyo kunokuphucula ukunyamezela.
Ukuthatha ii-NSAID kwisisu esingenalutho kwandisa umngcipheko wokuvelisa izilonda-nangona ukwenza ngoku ngokungenazo ingxaki. Ingxaki inokuthi ihlakulele. Ukuphepha ukuthinteka, qiniseka ukuba uthathe ii-NSAID ngokutya.
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Gwema izidakamizwa zeSteroid nge-NSAIDGwema iziyobisi ze-steroid (i-corticosteroids), ukuba kunokwenzeka, kunye ne-NSAID. Abanye oogqirha bangadibanisa umthamo ophantsi we- prednisone kunye ne-NSAID kodwa qwalasela ukungeza iPPI ukuba oku kuyimfuneko.
I-Coumadin kunye ne-NSAID nazo zisebenzisana nokwandisa umngcipheko wezilonda okanye i-bleeding. Thetha ugqirha wakho ngokunciphisa umngcipheko wakho wokuvelisa izilonda zegazi xa uthatha ii-NSAID. Ingxoxo ebalulekileyo kufuneka ube nayo nogqirha wakho.
Impendulo eyanikwe nguScott J. Zashin, MD, uprofesa oncedisayo wezonyango kwiYunivesithi yaseTexas Southwestern Medical School, iCandelo leRheumatology, eDallas, eTexas. UDkt. Zashin naye uhamba noogqirha kwii-Hospital zasePresbyterian zaseDallas nasePlano. Ungumntu we-American College of Physicians kunye ne-American College of Rheumatology kunye nelungu le-American Medical Association. UDkt. Zashin ngumlobi weArthritis ngaphandle kobuhlungu - Ummangaliso we-Anti-TNF Blockers kunye nombhali-mbhali we-Natural Arthritis Treatment.