I-Celebrex: I-NSAID ye-COX-2 ekhethiweyo isetyenziswe ukunyanga iArthritis
I-Celebrex (celecoxib) yiyona kuphela i-NSAID ekhethiweyo ye-COX-2 njengamanje kwimarike e-United States. Ii-NSAID ezikhethiweyo ze-COX-2 zithathwa ngokungenakwenzeka ukuba zenze iingxaki zesisu kunezi- NSAID zendabuko - amayeza athandwayo asebenzisa unyango lwe-arthritis. Nangona kunjalo, yonke i-NSAID inomngcipheko wegazi ophezulu, iingxaki zeengtso, ukugcinwa kwamanzi kunye neengozi zentliziyo.
I-Celebrex yavunywa ngo-Disemba 31, 1998, yi-United States Yokutya kunye neDrug Administration (i-FDA) yokukhupha impawu kunye neempawu ze- osteoarthritis kunye ne- arthritis yabantu abadala. I-Celebrex ithengiswa yiPfizer.
Yintoni ukufumaneka kweCelebrex?
I-Celebrex ayitholakali njengelinye izidakamizwa. Itholakala kuphela ngomyalelo. I-Celebrex inamandla amakhulu-100 mg kunye no-200 mg. I-dose yemihla ngemihla ekhuthazwayo ye-osteoarthritis ingama-200 mg, ithathwa njengowodwa umthamo okanye kwi-100 mg imiqathango kabini ngosuku. Ugqirha wakho uya kugqiba isigqibo esifanelekileyo sakho kunye nemeko yakho.
Ngabe iCelebrex imiselwe nini?
I-Celebrex imiselwe ukuba inciphise iimpawu ze-osteoarthritis kunye nokuphucula iimpawu zesifo se-rheumatoid kubantu abadala. Kwakhona kusetyenziselwa ukulawula intlungu ebuhlungu kubantu abadala (njengokulandela amazinyo okanye iinkqubo zokugqirha), nokunciphisa inani lamakoloni kunye nokukhula kwamagciwane kwizigulane ezine-FAP (i-Adenomatous Polyposis).
Ngaba ikhona imiyalelo ekhethekileyo malunga nendlela yokuthatha iCelebrex?
I-Celebrex kufuneka ithathwe ngokuchanekileyo njengoko imiselweyo. Ukuthatha iCelebrex ngeglasi yamanzi okanye ukutya kunokuthintela isisu.
Ngaba kukho izigulane ezingafanele zithathe iCelebrex?
Izigulane ezithintekayo kwi-sulfa akufanele zithathe iCelebrex.
Kwakhona, izigulane ezinobomi be-aspirin akufanele zithathe iCelebrex. Izigulane ezinobomi be-Aspirin yibo abaye bafumana imingxuma, isifo se-asthma, okanye i-reaction-type response reaction after taking aspirin okanye ezinye ii-NSAID.
I-FDA ikhuphe isilumkiso ngo-Ephreli 7, 2005, malunga neengozi ze-cardiovascular (ezifana nokuhlaselwa kwentliziyo kunye nokushaya kwesisu) ezibandakanya neCelebrex kunye nezinye ii-NSAID. I-FDA icebisa oogqirha ukuba baqikelele ngokucacileyo iingeniso kunye neengozi zeCelebrex kunye nezinye iindlela zokonyango ngaphambi kokuba kwenziwe isigqibo sokusebenzisa iCelebrex.
I-FDA kunye nomenzi weCelebrex iyavuma ukuba kusekelwe kwingcaciso ekhoyo, i-Celebrex imele idayiswe. Nangona kunjalo, izigulane ezinobungozi obukhulu bokuhlaselwa intliziyo okanye ukubetha kufuneka ziqwalasele izilumkiso kunye nezinye iindlela zokunyanga.
Ziziphi iimpembelelo eziqhelekileyo ezivela kwiCelebrex?
Ezinye zeempembelelo eziqhelekileyo ezichaphazelekayo neCelebrex ziquka:
- intloko
- ukunyanzelisa
- isifo sokuphefumula esiphezulu
- isifo sohudo
- ukuvutha kwesono
- intlungu yesisu okanye isicupunu
Ziziphi ezinye izilumkiso ezikhethekileyo kunye nezilumkiso ezisetyenziswa kwiCelebrex?
Kukho iingozi ezinzulu ezinxulumene neCelebrex kunye nezinye ii-NSAID. I-Celebrex okanye ezinye i-NSAID zingabangela izilonda zesisu. Shayela ugqirha wakho xa ubona ukunyuka kwamathumbu amnyama, ukuhlanza igazi okanye ukuhlanza okubukeka njengeendawo zekhofi, okanye ubuhlungu besisu.
I-Celebrex kunye nezinye ii-NSAID zingabangela ukulimala kwesibindi. Izilumkiso zesibonakaliso somonakalo wesibindi ziquka i-nausea, ukuhlanza, ukukhathala, ukulahleka kwesidlo, ukukhwabanisa, isikhumba esifutshane okanye amehlo, umchamo omnyama, iimpawu ezinjenge-flu. Biza ugqirha wakho ukuba unayo nayiphi na le mpawu.
Iingxaki zeengso zingenzeka nge-Celebrex okanye i-NSAID-okanye ukungaphumeleli kwintlungu ngokukhawuleza okanye ukuxhatshazwa kweengxaki zezintso ezikhoyo.
Ukugcinwa kwe-Fluid kungenziwa ngeCelebrex okanye i-NSAID. Kungaba nzima ukuba unomfutho ophezulu wegazi okanye ukukhubazeka kwentliziyo.
Ngaba kukho ukusebenzisana kweziyobisi ezihambelana neCelebrex?
Kubalulekile ukuxelela ugqirha wakho malunga nawo onke amayeza owathathayo.
Amanye amayeza angachaphazela indlela iCelebrex esebenza ngayo kunye neCelebrex inokuchaphazela indlela amanye amayeza asebenza ngayo. Iziyobisi ezinokusebenzisana neCelebrex ziquka:
- ACE inhibitors (imishanguzo yegazi)
- furosemide
- i-fluconazole okanye i-ketoconazole
- lithium
- phenytoin
- warfarin
- aspirin
Ngaba kukho imiyalelo ekhethekileyo yabasetyhini abakhulelweyo okanye abahlengikazi?
Abasetyhini abakhulelweyo, kwaye ngakumbi abo kwiinyanga ezintathu zokugqibela, akufanele bathathe iCelebrex. Thetha ugqirha wakho ukuba ukhulelwe, uzama ukukhulelwa, okanye ukuncelisa.
Ziziphi iimpawu zokudlula ngaphezulu kweCelebrex?
Njengoko nawaphi na amayeza, imiphumo emibi ingabangela ukugqithisa kweCelebrex. Iimpawu ezilandelayo zingenzeka nge-Celebrex overdose: ukuphefumula, iimvakalelo, ukuxubha, isisu, ukuhlanza, isisu esiswini, ukuphuma kwegazi, ukunyanga kwegazi, ukungaphumeleli kwezintso. Sebenzisa i-Celebrex nje ngokuyalelwe ukuba ugweme ukudlula.
Imithombo:
Celecoxib (ithengiswa njengeCelebrex). Iphepha leNgcaciso loMgcini we-FDA. 4/7/2005.
Celebrex. PDRHealth. Ufikelele kwiDisemba 30, 2015.