Izibonelelo zifikelela kwiiRiliyoni ezingama-20 kwii-US zonyaka
Ukutya okuncedayo kwiibhiliyoni zeedola ngokuthengiswa kwonyaka kwi-United States. Uninzi lwesithathu kwisigulane se- osteoarthritis sele sisetyenzisiwe.
Ukuncedisa ukutya kunokungavumelekanga. Zingathengiswa ngophando oluthile lwezenzululwazi ukuxhasa ukukhusela kwabo kunye nokusebenza kwabo.
Ukususela ngo-2000, kuye kwaba nama-800 e-supplementary formulations formulations aimed to relieve osteoarthritis.
Nangona ezinye zazo zibhekwa njengezikhuselekileyo kwaye zisebenzayo, abaninzi abanakuza kunye nesiqinisekiso. Makhe sijonge kwiindawo zokutya ezidumileyo ezisetyenziswayo kwi-osteoarthritis.
Glucosamine
I-Glucosamine yindlela yokutya edla ngokuqhelekileyo isetyenziswa ngabagulane be-osteoarthritis. Umzimba uvelisa i-glucosamine ngokwabo, kwakhona, kwaye ufumaneka kwiindawo eziphakamileyo kwiindawo. Kwiingcamango, i-glucosamine ivuselela ukubunjwa kwe-cartilage ebalulekileyo ekulungiseni ngokuhlangeneyo. I-Synthetic glucosamine, okanye leyo evela kwi-shellfish exoskeletons, ingaba nezixhobo ezichasayo.
I-Glucosamine ifumaneka njenge-glucosamine hydrochloride kunye ne-glucosamine sulfate. Ithengiswa ngokuhlanganisana nezinye izongezo zokutya, nazo. Kuye kwafundwa ngokubanzi kwi-osteoarthritis (izifundo ezilawulwa ngu-20 kunye nabathathi-nxaxheba abangaphezu kwe-2,500). Ininzi yophando igxile kwi-glucosamine sulphate njengonyango lwe-osteoarthritis yamadolo kunye ne- hip .
Ngelishwa, iziphumo zophando azihambisani.
Ngo-2005, ukuhlaziywa kwezilingo ze-glucosamine kwi-osteoarthritis kwagqiba ukuba i-glucosamine inciphisa kakhulu intlungu ye-osteoarthritis. Uhlobo lwe-glucosamine lwalisebenzisayo lubonakala lubonisa umehluko. UDona, umkhiqizo we-glucosamine sulfate, ufumene ukunciphisa kakhulu intlungu ye-osteoarthritis.
Olunye uhlalutyo, olubizwa ngokuba yi- Glucosamine / Chondroitin I-Arthritis Intervention Trial (GAIT) , lisetyenziswe i-glucosamine hydrochloride. I-Glucosamine hydrochloride esetyenziswe yedwa okanye idibene ne-chondroitin ayizange iyanciphise iimpawu ze knee osteoarthritis. Kodwa kunjalo, ukunciphisa intlungu kwezinye izigulane ezinezifo ezinzima zesifo.
Xa kuthelekiswa ne- acetaminophen okanye i- NSAID , i-glucosamine sulfate iboniswe ukuba isebenze ekunciphiseni ubuhlungu nokuphucula umsebenzi ohlangeneyo. Ezinye izifundo zibonise ukuba i-glucosamine sulfate inciphisa kakhulu indawo edibeneyo emadolweni emva kweminyaka emithathu yonyango.
I-Glucosamine ithathwa njengekhuselekile ukuyisebenzisa. Iziphumo ezibonakalayo kwizifundo zazifaniswa ne-placebo kwaye ngokwenene ziphantsi kunezo zibonwe nge-NSAID.
Chondroitin
I-Chondroitin yi-glycosaminoglycan-isakhiwo sokwakha isakhiwo esibambene. Ukuthengisa, ngokuqhelekileyo kudibaniswa nezinye izongezelelo, kodwa izifundo zijolise kwi-chondroitin yodwa.
Kukho uphando oluncinane kwi-chondroitin kune-glucosamine sulfate. Iziphumo zoFundo ziye zingavumelani. Izilingo zokuqala (1980 ukuya ku-2001) zityhile ubungqina bokuba i- chondroitin inciphisa intlungu kwaye yanciphisa indawo edibeneyo. Uphando olutshanje, ukususela ngo-2005, lube luhle kakhulu, olugqiba ukuba i-chondroitin ayizuzisi i-osteoarthritis.
Abaphengululi baphetha ngokuthi i-chondroitin ayinamandla ngakumbi kune-glucosamine sulfate. Akukho bubungqina obubonisa ukuba ukudibanisa i-chondroitin kunye ne-glucosamine sulfate kunika into engcono kunokuba i-glucosamine sulfate yodwa.
SAM-e
I-SAM-e, emela i-S-adenosylmethionine, iveliswa kwisibindi ukusuka kwi-methionine. I-SAM-e icingelwa ukuba yandisa i-chondrocytes kunye ne- cartilage ubukhulu, kwaye inokunceda ukunciphisa umonakalo we-chondrocyte.
Uphando lwe-SAM-e lwe-osteoarthritis luye luyafana kwaye lulungile. I-SAM-e ifunyenwe iphumelele ngakumbi kune-placebo kwaye ifaniswe ne-NSAID ye-relief osteoarthritis.
Uvavanyo olutshanje lunokufanisa i-SAM-e kunye neziyobisi zeCelebrex (celecoxib). Ngenyanga yokuqala, i-Celebrex yayiyinkqubo yokuphucula ubuhlungu ngaphezu kwe-SAM-e, kodwa kwakungekho umahluko phakathi kwe-SAM-e neCelebrex ngokweentlungu zentlungu emva kweenyanga ezimbini zonyango. Basebenza ngokulinganayo.
I-SAM-e ithathwa njengekhuselekile, kodwa ingabangela ukuxhalaba, intloko, ukungabikho kokusabalalisa kunye nokukhathazeka kwezinye izigulane. Ingakwazi ukusebenzisana nezinye iziyobisi, kuquka i- Ultram (tramadol). Ufanele uxoxe nge-SAM-e kunye nogqirha wakho ngaphambi kokuba uyithathe. Iindleko kunye nomgangatho wemveliso sele zikhankanywe njengezinto ezimbi ze-SAM-e, nazo.
MSM
I-MSM (i-methylsulfonylmethane) iyafumaneka ngokutya kwabantu. Itholakala kwizityalo, izithelo, imifuno, inyama kunye nobisi. I-MSM ifumaneka kwi-adrenal gland. I-MSM icingelwa ukuba inempahla echasayo. Iziphumo ezivela kwizifundo ezimbini ze-MSM zityhila ukuba i-MSM yanciphisa ngokukhawuleza intlungu kunye nokuvuvukala, kodwa ayizange inciphise ukuqina okuhlangeneyo.
I-MSM ithathwa njengekhuselekile kwaye ibekezeleke kakuhle nemiphumo efana ne-placebo. Uvavanyo lwezonyango aluzange lube lide elide, nangona kunjalo, lugcine iiveki ezili-12 okanye ngaphantsi. Kufuneka kwenziwe uphando lwexesha elide.
Umoya kaMtyholi
Isihlunu sikaMtyholi sithathwe kwisityalo saseAfrika. Iintlobo zokusebenzisa i-claw kaMtyholi zibangelwa yimiphumo yokuchasa; inqanda i- COX kunye ne-lipoxygenase, nangona kuthiwa inqanda i-COX-2 kwaye ingekho i-COX-1. Izifundo ezimbalwa zeklinikhi zithole ukuba izicatshulwa zikaMtyholi, ezithathwe yedwa okanye nge-NSAID, zanciphisa intlungu ye-osteoarthritis kwaye yayinyamezeleka. Kufuneka uphando olongezelelweyo ukuvavanya ukusebenza kwalo kunye nokukhuseleka kwexesha elide ngaphambi kokuba kunconywe ngokunyanisekileyo.
I-Turmeric
I-Turmeric yi-spice esetyenziswe kwi-curry powders. I-Curcumin, i-pigment enika umbala ophuzi ukutya, isisithako esisebenzayo kwi-turmeric. I-Curcumin inezixhobo ezichasayo, njengoko zivimbela i-COX-2, i-prostaglandin kunye ne-leukotrienes. Kodwa, akukho zilingo zekliniki ziye zavavanya i- turmeric kwi-osteoarthritis . Kuze kubekho uphando olongezelelweyo lwenziwe, i-turmeric ayikhuthazwa ukuba i-osteoarthritis.
Ginger
I-Ginger ingaba nemiphumo echasayo ngenxa yokuvinjelwa kwe-COX kunye ne-lipoxygenase. Iyakuchukumisa i-tumor necrosis factor (i- cytokine ), kunye ne-synthesis ye-prostaglandin evuthayo. Akukho bungqina obuxhasa ukukhuthaza iginki ye-osteoarthritis.
Ngaphantsi
Xoxa ngezongezelelo kunye nodokotela wakho ngaphambi kokuchitha imali kubo.
Umthombo:
Izibonelelo zokutya ze-Osteoarthritis. UP. Gregory, uMnu Sperry, uA. Wilson. WaseMerika ugqirha . NgoJanuwari 15, 2008.
http://www.aafp.org/afp/20080115/177.pdf