Iingxaki nge-Gait, Ukulinganisa kwiZityholo, Ezinye iimpawu eziqhelekileyo
Iimpawu ze-gluten ataxia, imeko ye-neurological ephumela ekuphenduleni kwiprotheni ye-gluten , inokuvela kwiinkalo zobunzima bokuqhubeka kunye nokungaqiniseki kwiinyawo zakho kwiingxaki zokugwinya. Unokuba nombono ombini, okanye nemiba yokulawula isilwanyana sakho.
Iimpawu zakho ziza kuhamba ngokukhawuleza okanye zingabonakala ngokukhawuleza, kodwa mhlawumbi aziyi kubandakanywa iimpawu zokutya ezingabonakalisa isifo se- celiac .
Abaphandi baqala ukuchaza i- ataxia ye-gluten , kwaye akubona bonke oogqirha abaqhelekileyo abavuma ukuba sisifo esilungileyo. Ukongezelela, ayikho imvavanyo yezokwelapha eyaziwayo ukuxilonga i-ataxia ye-gluten, nangona abaphandi abaphezulu besifo se-celiac ne-non-celiac- sensitive gluten bacebise inkqubo yokuxilonga abantu abakrokrelwa ukuba nabo.
Nangona kunjalo, uphando oluthile lwezonyango luye lwachazela iimpawu ze-acuten ataxia, kwaye ziqikelele ukuba bangaphi abantu abanokuba ne gluten ataxia .
Iimpawu zeGluten Ataxia zibandakanya iingxaki zeengxaki, ukungaqiniseki
Iimpawu ze-ataxia ye-gluten zifana nezo zenye i-ataxia, okwenza kube nzima ukubonelela ngokufanelekileyo. Izigulane ze-gluten ataxia ngokubanzi zisekupheleni kweminyaka engama-40 okanye kwiminyaka eyi-50 xa sele zifunyenwe, nangona uphando lwezonyango lubhala amanqaku amaninzi apho imeko ikhula kubantwana abaselula okanye abatsha. Amadoda nabasetyhini bamelwe ngokulinganayo (ngokungafani nesifo se-celiac, apho abafazi banamadoda amaninzi ).
Kwiimeko ezininzi, abantu baqaphela iingxaki ngezakhono zabo zokuqala zezithuthi-ngamanye amagama, baya kuba banzima kakhulu, baya kuhamba ngokukhawuleza kunye nokuthambekela kokukhubeka okanye benze izinto ezimbi, kwaye ngokuqhelekileyo baya kuba bengaboni kakuhle.
I-Gluten ataxia abanesifo banokuphawula iingxaki kunye nezakhono ezintle zezithuthi-umzekelo, umntu onesi simo angenakukwazi ukululaza i-shirt okanye ukusebenzisa ipeni ukubhala ixesha elide.
Ezinye izigulana nazo zidibanisa amagama abo okanye zinengxaki yokuthetha, kwaye abanye banzima ukugwinya.
Iingxaki zeNkcitho ziza kuqala
Uphononongo lwezokwelapha lubonisa ukuba wonke umntu one-gluten ataxia eneempawu zokufumana i-ataxia, kwaye ukuba ezi ngxaki zihlala zihamba kunye nezibonakaliso ze-gluten ezinxulumene ne-neuropathy (oko kukuthi, ukugubungela kwimida yakho). Phantse i-80% ineengxaki ngamehlo abo, apho amehlo abo ahamba khona ngokungahambiyo.
Phantse i-60% yezigulane zibonisa ubungqina bento ebizwa ngokuba yi "sensorimotor axonal neuropathy," oku kuthetha umonakalo wento obangela ukuvakala kwengxaki, ukulahlekelwa kwintlungu kunye nentlungu ekupheleni. Nangona kunjalo, ezi zibonakaliso zisoloko zincinci, kwaye azinakuthi zinegalelo kwi-ataxia, abaphandi bathi.
Ngaphandle kwendalo enokubangela imonakalo emizimbeni yabo, kuphela malunga no-10% wabantu abane-gluten ataxia baya kuba neempawu zesisu ezinjenge-diarrhea, ukuqothulwa , ukubetha, isisu, isisu kunye ne- reflux . Nangona le nqanaba eliphantsi leempawu, olunye uphando lufumene ukuba i-24% yezigulane zase-gluten i-ataxia empeleni yayine- horrogetic inrophy ezivela kwisifo se-celiac.
Iimpawu zibonakalisa ukulimala kwi-Brain yakho
Zonke ezi zimpawu ze-gluten i-ataxia zivela kumonakalo kwi-cerebellum yakho, inxalenye yengqondo yakho ehlawulwe ngokuqinisekisa ukuba imisipha yakho isebenza ngokubambisana.
Enyanisweni, i-60% yezigulane ezixilongwa nge-gluten ataxia zinobungqina bokuthi i-cerebellar i-atrophy-ngokoqobo, i-shrinkage yaloo nxalenye yobungqina babo-xa ihlolwe yi-imaging magnetic resonance (MRI). Izigulane ezingenayo i-shrinkage ebonakalayo kwi-cerebellums yazo zibonisa ukungavumelekanga kwizifundo zengqondo ezinzulu kakhulu, ngokutsho kwabaphandi.
Isimo sithatha ukuqhubela phambili, kodwa kunokwenzeka ukuba ihambe ngokukhawuleza, kunye ne-cerebellar atrophy ephuhliswayo kunyaka weempawu zokuqala, ngokutsho kukaDkt. Marios Hadjivassiliou, i-neurologist esebenza e-UK kunye nomphandi ophezulu kwintsimi ye-gluten ataxia.
Uhlolisiso olwenziwe nguDkt. Hadjivassiliou ukhangela izigulane ezingama-68 ezine-gluten ataxia zathi i-78% yalabo bantu bathatha enye okanye zombini izifo zezilwanyana eziphambili ze- ecliac , i- HLA-DQ2 kunye ne- HLA-DQ8 . Intsalela yeli qela iqhube i-HLA-DQ1, eyayiyicacise ukuba uDkt Hadjivassiliou ibonakalisa iimpawu ze-neurological from gluten ingestion .
ILizwi
Kwiphepha elipapashwe kwiphephancwadi le- BMC Medicine , uDkt. Hadjivassiliou kunye nabanye abaphandi abaphezulu baphakamise iimpawu eziqhelekileyo ze-gluten ataxia kwaye bacebisa i-algorithm yokuxilonga eyenzelwe ukuhlukanisa imeko nakwezinye iimeko zoguten neengqolowa: isifo se-celiac, gluten uvakalelo , i- dermatitis herpetiformis kunye nengqolowa yokunyuka kweengqolowa.
Nangona kunjalo, uphando olongezelelweyo kunye nokuvumelana kuya kuyadingeka ngaphambi kokuba oogqirha bafumane ngokupheleleyo i-gluten ataxia njengendlela yokuxilongwa, kwaye bavavanye rhoqo abantu ukuba babonisa iimpawu.
Ukuba ukholelwa ukuba unokufumana iimpawu ze-acutayxia ye-gluten, kufuneka uqale uthethe ugqirha wakho malunga neemeko kunye nokuba yikuphi okuvelele. Ezinye iimeko ezininzi, kubandakanywa nezinye i-ataxia, zingenza iimpawu ezifanayo. Kwakhona, akufanele uqale ukutya okungekho gluten ngaphambi kokuba uthethe nodokotela wakho, ekubeni ukususa i-gluten kunokukwenza iziphumo zakho zokuvavanya izifo ezingenakulinganiswa.
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