Ezi mvavanyo zinokunika iinkcukacha malunga nokuba unemeko
Uphando olutsha lwezokwelapha lunikezela inkxaso kwingcamango yokuba ubuninzi bobubele be- gluten bunyani ngokwenene. Nangona kunjalo, akubona bonke oogqirha abavuma ukuba kukho, kwaye akukho mvumelwano malunga nendlela yokuvavanya uvelwano lwe-gluten.
Ngoko ukuba uyakrokrela ukuba unobuncwane obunomdla, uhlala phi? Unenqweno emibini enokubangela ukukhanya kwimeko yakho, kuquka inketho enye yokuvavanya onokuzifumana ngaphandle kokuba ugqirha wakho ubandakanyeka.
Akukho nanye kwezi zikhetho eziza kubonisa ngokuqinisekileyo ukuba unobuncwane obunomdla-gulen-kwaye mhlawumbi akuyi kunika ukuxilongwa kwakho ugqirha uya kwamkela. Nangona kunjalo, olu vavanyo lwe-gluten luyakunikela ubungqina bokuba umzimba wakho uphakamise ukumelana nomzimba wamagciwane kwi-gluten ... engabonisa ukuba ukutya okungahambisani ne- gluten kunokukunceda ukulawula iimpawu zakho zobunene be-gluten .
Ukulumkisa: amaninzi amagqirha ancomela ukuba uqale uvavanyo lwe- celiac lweengxaki xa ucinga ukuba usabela kwi gluten. Sekunjalo, ukuba iziphumo zakho zokuhlola izifo zibi (okanye ukuba unqumle ukungayi kuhlolwa ngokupheleleyo), unokufumana olu vavanyo lwe-gluten uvavanyo lokubonelela ngolwazi oluncedo.
Iingcingo zegazi zeCeliac Kungenzeka ukuba zisetyenziswe ukufumana ukuqonda kweGluten
Ngaphambi kokwenza i-endoscopy kunye ne-biopsy ukufumanisa izifo ze-celiac, amagqirha ngokuvamile asebenzisa iphaneli yeimvavanyo zegazi ezingapheliyo ukuze afune i-antibodies ezibonakalisa imeko.
Kukho ubungqina bokuba ezimbini zezo vavanyo - i-AGA-IgA kunye ne- AGG-IgG- ingabonisa ukungahloniphi kwe-gluten.
I-AGA imela "i-anti-gliadin antibodies," okanye umzimba owenzela umzimba ngokumelene ne-gliadin, inxalenye ye-molecule ye-gluten. I-IgA ne-IgG ziintlobo ezahlukeneyo ze-immunoglobulin, iintsholongwane ezenziwa ngumzimba wakho ukulwa nabahlaseli bamanye amazwe.
Ukuba i-AGA-IgA okanye i-AGA-IgG ikhona egazini lakho, ithetha ukuba umzimba wakho wenza isifo se-antibodies malunga ne-molecule ye-gluten - ngamanye amagama, ibona i-molecule njengengozi.
Amanqanaba aphakamileyo ye-AGA-IgG atholakala kwi-10% yabantu bonke kwaye ngokuphindaphindiweyo kubonakala kwezinye izifo ezizimele , ezifana nesifo sikashukela se-type 1, isifo sesifo se-thyroid, isifo se- hepatitis, kunye nezifo ezifayo.
Uphando lwe-Gluten uphando olushicilelwe ngo-2011 yi-University of Maryland ye-Celiac Research lubone ukuba malunga nesiqingatha sezigulane ezinobulunga-gulen ezixilongwe zivavanyelwe i-AGA-IgA okanye i-AGA-IgG, ebonisa ukuba amajoni abo omzimba asabela kwi-gluten. Amanye amagqirha, kubandakanya umphandi wezilwanyana kunye nomlwankqulwazi we-gluten uDkt. Rodney Ford eNew Zealand, naye usebenzise uvavanyo lwe-AGA-IgG ukujongana noveliso lwe-gluten.
Nangona kunjalo, uDkt. Alessio Fasano, intloko ye-University of Maryland yaseburhulumenteni yophando, wandixelela kwingxoxo yokuba i-AGA-IgA kunye ne-AGA-IgG yeemvavanyo zegazi kuphela "njengezikhundla. Iqiniso lokuba malunga nesiqingatha sezigulane zentsholongwane ye-gluten ezivavanyelwe i-AGA-IgA kunye ne-AGA-IgG iintsholongwane zenza loo mvavanyo emibini ingabalulekanga kangangoko njengemvavanyo yokuvelisa i-gluten, uthi.
I-EnteroLab Iziphakamiso Okwangaphandle-Ukuvavanywa okungavumelekanga kwe-Gluten Sensitivity
Ezinye izigulane ezikholelwa ukuba zisabela kwi gluten ziphendulela uvavanyo lwe-EnteroLab gluten .
I-EnteroLab, i-laboratory yezobugcisa e-Dallas ejongene nokuhlalutya "iisampuli zamathambo" (oko kukuthi, iisampula zesitampu) ukukhathazeka kokutya, unikezela ukuhlolwa kokuhlola ukuxilongwa komthengi, kwaye izigulane ezininzi ziye zavakalisa ukukhulula ekuveleni kwabo kwe-gluten iimpawu emva kokuvavanywa kakuhle kwaye emva koko kususa i-gluten kwizidlo zabo.
Nangona kunjalo, inkqubo yokuhlola i-EnteroLab, eyenziwa ngu-gastroenterologist uDkt. Kenneth Fine, akayi kuhlolwa ngaphandle kunye nokuqinisekiswa, kwaye uDkt Fine uye wagxeka kakhulu kwamanye amagqirha nakubantu basekuhlaleni abanokuthi bangabonakali uphando kunye neziphumo.
Ngenxa yoko, bambalwa oogqirha baya kwamkela uvavanyo lwe-EnteroLab njengobungqina bentshukumo ye-gluten.
Uvavanyo lwe-entolab lwesigxina lubheka i-antibodies ukuba i-gluten ngqo kwi-intestinal tract. UDkt. Fine utshilo kum ndlebe ndlebe ukuba le ndlu ibheka i-antibodies apho iphendulelo langempela lwenzeka khona - emathunjini akho - ngokuchasene negazi lakho, apho kungabincipha khona. Kwakhona uthe ukukhohlakala ukucinga ukuba i-gluten, ekholelwa ukuba yi-antigen enamandla, yodwa ingabangela isifo se-celiac , kwaye ingekho enye impawu engahambelani ne- illiac inrophy .
Yintoni Ongayenza Ngoku Ukuvavanya Ukunyamekela KweGluten?
Okwangoku, abo bagqirha abafumanisa ukuzwela kwe-gluten banokwenza oko kuxhomekeke kwiziphumo ezivela kwi-AGA-IgA kunye ne-AGA-IgG yegazi, uvavanyo lokungena kwi-Enterolab, okanye ukutya okungekho ngaphandle kwaye ubuyisele kwakhona i-gluten.
Akukho nanye kwezi zikhethiweyo eziqinisekisiweyo ngophando oluzimeleyo. Nangona kunjalo, ukuvavanya ubuninzi be-gluten kusebuncinaneni bakhe ngexesha. Ukuba ngabaphandi bezonyango banelisekile kukuba imeko ikhona, mhlawumbi iimeko ezingcono, ezichanekileyo ziya kuphuhliswa kwikamva.
> Imithombo:
> J. Biesiekierski et al. Iinjongo zeGluten Iimpawu zoBuncwane kwiZifundo ezingekho phantsi kwezifo ezi-Celiac: I-Trial-Blind i-Randomized Trial-Controled Trial. I-American Journal yeGastroenterology. Ishicilelwe kwi-intanethi ngoJan. 11, 2011. i-doi: 10.1038 / ajg.2010.487.
> A. Fasano et al. Ukutshatyalaliswa kwamathambo okubonakalayo kunye ne-mucosal gene gene expression) kwiimeko ezimbini ezinxulumene ne-gluten: isifo se-celiac kunye nobutyebi be-gluten. I-BMC Medicine 2011, 9:23. i-doi: 10.1186 / 1741-7015-9-23.
> Fasano A. et. al. Isibuko seengxaki ezinxulumene ne-gluten: ukuvumelana malunga nokutyunjwa kwamagama omtsha kunye nokuhlelwa. BMC Medicine. I-BMC Medicine 2012, 10:13 i-doi: 10.1186 / 1741-7015-10-13. Ishicilelwe: 7 Februwari 2012
> E. Verdu. Ngaba i-gluten ingaba negalelo kwi-Irritable Bowel Syndrome? I-American Journal yeGastroenterology. Matshi 2011, iphe. 516-518.