Kuyavunywa ukuba umntu one-133 unesifo se-celiac , imeko yezofuzo ezibangelwa umonakalo wamathumbu nanini na xa zingenayo i- gluten , iproteni efunyenwe ngqolowa, i-hareyi ne-rye.
Nangona kunjalo, abaphandi baye bafumanisa ubuzwe obuninzi be- gliten njengemibandela eyahlukileyo, eyahlukileyo, kunye neyezinye kwiindawo zonyango balinde ukuqinisekiswa kwezi ziphumo ezintsha zophando ngaphambi kokuba bamkele uvelwano lwe-gluten njengesifo esilunokwenzeka.
Kwakhona kunokwenzeka ukuba akusiyo i-gluten emva kwayo yonke into-endaweni yoko, kunokuthi ibe yinto enye yengqolowa kunye nezinye izityalo ezinobulunga ezibangelwa ezinye okanye zonke iziganeko kubantu "abaguten".
Ukunikezelwa konke oku, kunye nokubakho ukuba akukho vavanyo olwamkelekileyo lwe-gluten sensitivity , akunakwenzeka ukusho ngokuqinisekileyo ukuba bangaphi abantu abanokuthi babe ne-gluten-sensitive. Abaphandi baqikelele ukuba kungaphantsi kwe-0.6% yabemi (okanye abayisithupha kubo bonke abantu abayi-1 000) okanye ngaphezulu kwe-6% yabemi (abathandathu kubo bonke abantu abayi-100), kodwa akukabikho uphando oluchanekileyo manani.
Nangona kunjalo, abathathu abaphambili abaphandle kwintsimi - uDkt. Alessio Fasano, uDkt. Kenneth Fine, noDkt. Rodney Ford - bathetha ngokunje kunye nam bucala malunga nokuba iipesenti zingaphi. Qaphela nje ngaphambi kokuba ufunde ukuba iipesenti ezibhekisele zona zisekelwe kubo (uphando oluninzi olushicilelwe), kwaye alumeli umbono wezobugcisa.
UDkt. Fasano: I-Gluten Ukuzwela Ubungenza 6% ukuya ku-7%
UDkt. Fasano, umlawuli weeYunivesithi yaseMadrid Centre for Research Celiac, wapapasha isifundo sokuqala ejonge i-molecular for gluten sensitivity kunye nendlela ehluke ngayo kwisifo se-celiac. Kwakhona wathatha inxaxheba ekuphandeni ekugqibeleni ukuba iziganeko zesifo se-celiac sisinye kubantu abayi-133.
Ngokutsho kukaDkt. Fasano, uvelwano lwama gluten lunokuchaphazela abantu abangaphezulu kunezifo zeliliac. Uqikelele malunga no-6% ukuya ku-7% wabantu base-US abanokuba ne-gluten-sensitive, oku kuthetha ukuba abantu abayizigidi ezingama-20 e-United States kuphela banokuba nale mqathango.
Izibonakaliso zentlupheko ye-gluten kule ndawo zingabandakanya iingxaki zokugaya, izifo zentlungu, iimvumba kunye neempawu zesikhumba ezifana ne-eczema, ingqondo yengqondo kunye nokukhathala, uDkt. Fasano uthi. Phantse kwisithathu sezo afunyanwe njenge-gluten-sensitive sensitive report brain and headaches njengempawu, uthi.
Drs. I-Ford, I-Fine Itsho Ipesenti ingaba phezulu kakhulu ukuya kuma-50%
UDkt Ford, udokotela wezingane e-Christchurch, eNew Zealand kunye nomlobi we -Gluten Syndrome , uthi ukholelwa ukuba ipesenti yabantu abanokwenene-gluten-inokuthi iphakame kakhulu-mhlawumbi iphakathi kwe-30% ne-50%.
Uthi: "Baninzi abantu abagulayo," ushoyo. "Ubuncinane i-10% i-gluten-sensitive, kwaye mhlawumbi ifana ne-30%." Ndayifaka intamo yam emininzi edlulileyo xa ndathi ubuncinane i-10% yabemi i-gluten-sensitive. siphila. Siyakufumana ukuba ngaphezulu kwama-50% xa sigqiba ukuhlala kwiqela. "
UDkt Fine, i-gastroenterologist eyasungula kwaye iqondisa i-gluten yokuvavanya inkonzo yokuvavanya u- Enterolab , iyavuma ukuba ubuzwe bentlobo buba nefuthe kwi-half-population.
UDkt Fine uxolisa ukuba i-10% ukuya kwi-15% yabantu baseMerika banama-antibodies egazi (nokuba yi- AGA-IgA okanye i- AGA-IgG antibodies) kwi-gluten, eya kubonisa ukuba amasosha omzimba ayasabela kwiprotheni.
Enye ipesenti enkulu yamaMerika zineengxaki ezizenzekelayo, izifo zesifo seengqondo ezikhungathekileyo , izifo ezintle ezingapheliyo kunye / okanye i-colitis microscopic, ezenza zibe sebunciphekweni obukhulu bokukhathazeka kwe-gluten. Phantse kwi-60% ukuya kuma-65% abantu abanemiqathango yokuvavanya enokubaluleka kwe-gluten senzwa ngokusebenzisa i-Enterolab, uDkt. Fine uthi.
Okwangoku, malunga nama-20% ukuya kuma-25% abantu abangenazo iimpawu bafumanisa ukuba ne-gluten uzwela ngokusekelwe kwiziphumo zokuvavanya kwe-Enterolab, uDkt Fine uthi.
"Xa senza izibalo, safika kunye nenani eliphakathi kweyesibini li-gluten-sensitive," utsho.
Okwangoku, uDkt. Fine uthi ukholelwa ukuba umntu one-133 engqikelele kubantu abanesifo se-celiac banokuphakama kakhulu - "Ndicinga ukuba kufana nesinye kwi-200. kunye nokhetho olukhethekileyo. " Olunye uphando lubeke iziganeko zesifo se-celiac malunga nomntu omnye kwi-200 ukuya kwelinye kubantu abangama-250, kwaye uDkt Fine uthi ucinga ukuba ezo zichanekile.
Ziyintoni na ezi ziNombolo zoBuncwane beGluten?
Okwangoku, iipesentezi zabantu abanokuba nobutyebi be-gluten bamele ukucatshungulwa okucokisekileyo kwiindawo zala magqirha nabaphandi - izifundo azizange zenziwe ukuba zibonakalise ukuba zichanile okanye zichanekile.
Imithombo:
I-Czaja-Bulsa G. I-Celiac Gluten-senensitive-A-New Disease With Gluten Inxerance. Isondlo seNtsholongwane (i-Edinburgh, Scotland). 2015 Ngo-Apr; 34 (2): 189-94.
Fasano A. et al. Ukuchithwa kwe-Gut Ukuthetheka kunye ne-Mucosal Gene Immression Expression kwiimeko ezimbini ezidibeneyo zeGluten: Izifo eziCeliac kunye ne-Gluten Sensitivity. I-BMC Medicine 2011, 9:23. i-doi: 10.1186 / 1741-7015-9-23.
Fasano A. et. al. I-Spectrum ye-Gulen-Related Related Disorders: Ukuvumelana kwiNqununu yeNtsha kunye noHlelo. BMC Medicine. I-BMC Medicine 2012, 10:13 i-doi: 10.1186 / 1741-7015-10-13. Ishicilelwe: 7 Februwari 2012