I-Cystic fibrosis (iCF) isifo esizuze ilifa elibangelwa i- defective defect ephazamisa amandla omzimba ukuba athathe ityuwa kunye namanzi kunye nakwiiseli. Oku kubangela ukuba i-buildup ye-mucus ebunjiweyo ifake imiphunga kunye nezitho zokutya. Abantu abaninzi bayazibona i-cystic fibrosis njengesifo somphunga kodwa abazi ukuba i-mucus buildup ichaphazela ezinye iimbutho.
Amalungu achaphazelekayo yiCF afaka:
- Imiba
- Pancreas
- Ibindi
- Amathumbu
- Sinuses
- Izitho zokuzala
I-cystic fibrosis yenye yezona zifo ezixhaphakileyo ze-genetic kwaye zichaphazela malunga no-1 kuzo zonke iintsana ezingama-2500 ezelwe eMelika. Ixhaphake kakhulu kwiCaucasians kunye ne-Hispanics kwaye ayifumanekanga kubantu baseAfrika okanye baseAsia.
Iimpawu
Iimpawu zeCF ziyahluka ngokuxhomekeka kwisigaba sesifo kunye namalungu achaphazelekayo.
Izimpawu zokuqala:
- Ukwandisa ukutya
- Ukukhula okubi
- I-oily, bulky, ukunyuka kwefuthe lokunyuka
- Isikhumba esinambitha
- Ukukhwehlela rhoqo
- Izifo eziphefumula rhoqo
- Ukuphefumula okunzima
Izimpawu eziphambili zivela ngendlela yeengxaki, kubandakanywa:
- Ukulahleka kwesisindo esingachazwanga
- Sikashukela
- Pancreatitis
- Isifo sesibindi
- Ukungenzi lutho
Ukuxilongwa
I-Cystic fibrosis ifunyaniswa ngokuvavanya igazi, ukujuluka okanye iiseli ze-fetal ngenxa yobukho bezinto okanye izakhi zofuzo ezifumaneka kwizigulane zeCF.
Ukukhulelwa
Ukuba isibini esilindeleyo siyazi okanye sikhankanya ukuba singabathwali beCF , i-amniocentesis okanye i-chorionic villus sampling ingenziwa ngexesha lokukhulelwa ukuqinisekisa ukuba umntwana uya kuba nesifo.
Olutsha
Okwangoku, ama-40 aquka i-cystic fibrosis kwiimvavanyo zabo zokuzalwa . Igazi lithathwe kwisithende sesana ngaphambi kokuba ahambe ekhaya esibhedlele. Igazi lithunyelwa kwibhubhoratri yombuso kwaye ukuba i-defect iyifumene ugqirha wezempilo oyintloko kunye nee-arhente zempilo zendawo ziya kwaziswa.
Ubuntwaneni noBantwana
Ukuba ingabonakalwanga ngexesha lokuzalwa, i-cystic fibrosis ihlala ifunyaniswa ngunyaka wokuqala okanye ezimbini zobomi xa umntwana eqala ukubonisa iimpawu zokulumkisa eziqhelekileyo. Uvavanyo lwendabuko lwe-cystic fibrosis luvavanyo lwe-sweat. Ngenxa yokuba umzimba awukwazi ukusebenzisa zonke iityuwa eziyithathayo, abaninzi abantu abane-cystic fibrosis ngokuqhelekileyo bahlala bekhudlwana kunamanani aqhelekileyo atyuwa.
Ukuhlolwa kwesithukuthezi, i-electrodes ifakwe kwisikhumba isiguli ukuvuselela izigulane zomzimba. I-sweat iqokelelwa kwaye ithunyelwe kwi-laboratory ukulinganisa umxholo wetyuwa. Uvavanyo lwe-sweat alubuhlungu kwaye luye lwasetyenziswa iminyaka emininzi ukufumanisa i-cystic fibrosis.
Unyango
Akukho nonyango ye-cystic fibrosis. Unyango luquka ukudibanisa kwamachiza, ukutya, ukuzivocavoca, kunye nezonyango ezenzelwe ukulawula iimpawu nokukhusela iingxaki.
Amayeza anikezelwe ukuba:
- Ukukhusela nokulawula izifo zokuphefumula
- Gcina umoya ovulekile kwaye uncede ngokuphefumla
- Mkhulula uze ususe i-mucous encinci
- Nceda umzimba uthathe izondlo
Izicwangciso zokutya kunye nezondlo zimiselwe ukuba:
- Yenza iivithamini ezingenakugcinwa
- Qinisekisa ukuba i-calorie intake ihlangabezana neemfuno eziphezulu zamandla
- Ukuqinisekisa ukungenelela okunokondla okwaneleyo ukukhula okufanelekileyo nophuhliso
- Shintsha ityuwa elahlekile ngokukhupha
Ukuzivocavoca kunye nezokwelapha zimiselwe ukuba:
- Qinisekisa intliziyo nemiphunga
- Ukukhupha kunye nokucaca
- Ukuphucula ukunyamezela kunye nesimo somzimba jikelele
- Ukwandisa inani le-oksijini elinikezwa kwiiscupu
Izizathu
I-CF ibangelwa isiphako kwi-cystic fibrosis i-transmembrane conductance regulator ( CFTR ). Umsebenzi wegciwane leCFTR ukwenza iprotheni elawula ukuhamba kwetyuwa kunye namanzi kunye naphuma kuwo onke amaseli emizimbeni yethu.
Ngamnye wethu unakho iikopi ezimbini zegciwane leCFTR kuba sinalo omnye kubazali bethu. Ngamanye amaxesha i-CFTR yegciwane esiyifumana kubazali bethu ayinqabile, kodwa oko akuthethi ukuba siya kuba neCF.
Ukuba umntu uzuza ilifa:
- 2 eziqhelekileyo zegciwane le-CFTR: Akayi kuba neCF kwaye akayi kuba ngumphathiswa.
- 1 i-CFTR yegciwane kunye ne-1 engafanelekanga ye-CFTR gene: Akayi kuba neCF kodwa uya kuthwala i-gene engaphelele kwaye ayidlulisele kubantwana bayo.
- 2 izakhi ze-CFTR ezingaqhelekanga: Uya kuba nezifo zeCF.
Thintelo
Ngenxa yokuba i-cystic fibrosis isifo esizuze njengefa, asikwazi ukunqandwa. Nangona kunjalo, ubukho befayili ye-CFTR ephosakeleyo buyafumaneka ngovavanyo olulula lwegazi. Ngaphambi kokukhulelwa umntwana , izibini eziziwayo okanye ezikrokrelayo ukuba omnye okanye bobabini abalingani banokuthwala i-CF i-defect kufuneka bafune ukululekwa nge-genetic ukubeka umngcipheko wokudlula izifo ze-CF.
Ukuphila NgeCystic Fibrosis
Kwakungekadala kakhulu ukuba abantwana abane-cystic fibrosis babedla ubomi ngaphesheya kwexesha leshumi. Ngoku, into eninzi iyaziwa ngesifo esingaziwa ngaphambili. Olu lwazi lukhokele kwiimpawu zonyango ezivumela abantu abane-cystic fibrosis ukuba baphile ubomi obusebenzayo kwaye bevelise kakuhle baze babe ngabantu abadala. Abantu abahlala ne-cystic fibrosis kufuneka bathathe amanyathelo okuthintela ngokuchasene nezifo. Baya kufuneka kwakhona bathathe i- enzyme yokutya, i-antibiotics, kunye namanye amayeza abo bonke ubomi babo. Amadoda ayedla, abesifazana abanokuthi bancembe kodwa banako ukukhulelwa.
Ukuba Umntwana Wakho Uyabonwa
Ugqirha wentsapho okanye udokotela wezilwanyana uya kuqhubeka nokubonelela ngenkxaso ngoncedo lweqela leengcali. Mhlawumbi uya kukubhekisela kwiziko le-cystic fibrosis kwindawo yakho. Ukuba akunjalo, cela ukuthunyelwa. Amaziko e-Cystic fibrosis asebenza ngamagqirha kunye nabaqeqeshi bempilo abaqhelene nesi sifo kwaye baxhotyiswe ngokufanelekileyo ukubeka iliso kumntwana wakho kwaye banikeze unyango ngokubhekiselele kuphando olutshanje. Kwisiko, umntwana wakho uya kubona iqela lababoneleli kubandakanya i-pulmonologist (ingcali yempuphu) kunye nesondlo sokutya. Iziko le-cystic fibrosis yindawo enhle yokufumana ulwazi malunga noluntu kunye nezibonelelo zwelonke ezikhoyo kuwe.
Umthombo:
Icystic fibrosis . I-Heart Heart Lung neSigqeba seGazi: Izifo kunye nemiqathango ye-Index. Agasti 2007.