Ingxenye yangaphambili yeliso iquka ikamelo langaphakathi, i-cornea, kunye ne-iris. Ingaphezulu kwesigamu se- HIV- abangabandakanyiyo banokuthi bahlakulele inkcenkceshelo yecandelo elingaphaya eliphakathi kwamehlo omileyo ukuya kwiintsholongwane zentsholongwane.
Iintsholongwane zesohlo ezijongene neHIV
Intsholongwane echaphazelekayo ne-HIV enokuthi ibonakale kwingxenye yangaphambili iquka:
- Iridocyclitis, ukuvutha kwe-iris
- I-Keratitis , usulelo lwe-cornea
- I-Microsporidiosis , ukusuleleka kwe-fungal kuphazamisa kakhulu i-cornea
Iridocyclitis ukuvuvukala kwe-iris, enokuthi idibaniswe nenani lezonyango ezichaphazelekayo (i-OIs), kuquka i- cytomegalovirus (CMV) , i- virus ye-herpes simplex (HSV) , i- toxoplasmosis , isifo sofuba kunye ne- varicella yoster virus (VZV) . Ubunzima bokuvuvuka buhambelana ngokukhawuleza kwe-OI kwaye kaninzi luba ngumqondiso wokuqala wesifo esiphuthumayo. Amatyala awona matyala kakhulu athetha ukubandakanya izigulane ezinenani eliphantsi kakhulu le- CD4 .
U-Iridocyclitis unokubonakalisa ngenxa ye- syphilis , kunye neziyobisi ezifana ne-rifabutin (esetyenziswa rhoqo kwisifo sesifo sofuba) kunye ne-cidofovir (esetyenziselwa ukunyanga iimeko ezinzima ze-CMV).
U-Iridocyclitis angabonakalisa kwelinye okanye zombini amehlo, ngeempawu ezingabandakanyeka amehlo abomvu, ukukrazula ngokweqile, ukuqonda ukukhanya (photophobia) kunye nabafundi abanqongqo.
Iridocyclitis ijwayele ukuphucula unyango oluyimpumelelo lwe-antiretroviral kunye nokuphathwa kosulelo oluchongiweyo.
I-Keratitis yintsholongwane ye-cornea engabangelwa yi-HSV, i-VSV, i-candidiasis (isifo sosuleleko esibonakalayo rhoqo kubantu abanentsholongwane kaGawulayo), kunye nezinye izifo. Kwiimeko ezininzi, ukuxhatshazwa kwe-immunosuppist kudlulisela isigulane ku-keratitis, iimpawu ezingabandakanyeka amehlo abomvu, ukugqithisa ngokugqithiseleyo, intlungu yesohlo, umbono ophazamisayo, ukuqonda okukhanyayo (photophobia) kunye nomvakalelo wokuthobeka kwiso.
Ukunikezelwa kungabandakanyeka (kubandakanyeka kokubili amehlo) kwaye kungabandakanyekanga (kubandakanyeka iliso elinye). Iingxaki ezinokuthi zinokubangelwa zizilonda zamachiza kunye nokukhawuleza ukulahlekelwa yombono kunye nokuphosa.
Njengoko iridocyclitis, ukuqaliswa kweyeza-antiretroviral kunconywa ukunciphisa umngcipheko weengxaki, kunye nokunyangwa kosuleleko oluchongiweyo (ngokuqhelekileyo nge-acyclovir ye-HSV ne-VZV, okanye i- antifungal efanelekileyo kwiimeko ze-candidiasis).
I-Microsporidiosis yintsholongwane engumngcipheko, okwenzeka ngokuqhelekileyo xa isibalo se-CD4 yesigulane sehla ngaphantsi kweeseli ezili-100, mL. Nangona i-corneal infections ingabonakali kwiimeko ze-microsporidiosis, zingabonisa iintlungu zeso, ukugqithisa ngokugqithiseleyo, umbono obonakalayo kunye novelwano olukhanyayo (photophobia).
Ukongezelela ekuphumezeni unyango lwe-antiretroviral , i-microsporidiosis ivame ukuphathwa ngamachiza e-azole njenge-albendazole kunye ne-itraconazole. Amaconsi antifungal athile angasetyenziswa ngamanye amaxesha kunye ne-azole therapy.
Imithombo:
Cunningham, E. kunye noMargolis, T. "Ukubonakaliswa kweeYile kweso." I-New England Journal of Medicine. Julayi 23, 1998; 339: 236-244.
Parrish, C; O'Day, D .; kunye noHoyle, T. "I-Ulul Corneal ulcer ngokubonakalayo njenge-Ocular Manifestation of AIDS." I-American Journal ye-Ophthalmology. NgoSeptemba 15, 1987; 104 (3): 302-303.
Rocha Lima, B. "Ukubonakaliswa kwe-Ophthalmic kwi-HIV Infection." Digital Journal ye-Ophthalmology. Oktobha 29, 2004; 10 (3): inguqulelo ye-intanethi.
Sudhakar, P .; IKedare, iS .; kunye noBergger, J. "I-Neuro-Ophthalmology ye-HIV / AIDS Ukuhlaziywa kweNtsholongwane kaGawulayo ye-HIV." Iingxaki zeNtsholongwane kaGawulayo . NgoSeptemba 17, 2012; 2012 (4): 99-111.