Ukulala ngokugqithiseleyo kungenziwa ngenxa ye-Neurologic Condition
Ukuqhaqhaqhayisa ngenye yezinto ezincinci eziqondwa ngxaki zokulala. Ingakhokelela ekukhuseleni ngokuphawulekayo iimpawu, ezivela ekuhlaselweni ngokukhawuleza kokulala ebuthathaka obubizwa ngokuba yi-cataplexy ekhokelela ekugqibeleni ukuwa.
Nangona kungabonakali, yintoni i-narcolepsy? Ukwandisa ukuqonda kwakho ngeengxaki zezilwanyana ngokuhlola iimpawu, izizathu, ukuxilongwa, kunye nokunyangwa kweengxaki.
Iimpawu kunye nezixhobo zeNtshontshopsy
I-Narcolepsy yimeko yesifo se-neurologic esenza ukuba ubuthongo obukhulu kakhulu emini kunye nezinye iimpawu ngenxa yokungaphumeleli ukulawula iindawo zokulala nokuvuka. Ukuhluleka kubangela ukuguquka ngokukhawuleza ukusuka kwelinye ilizwe ukuya kwelinye. Oku kunokukhokelela ekungabuthathaka ngokukhawuleza ngoxa uphapheme (obizwa ngokuba yi- cataplexy ) okanye mhlawumbi ukukhubazeka okupheleleyo, njengokuba kuya kwenzeka ukuba kuthintele umntu ukuba asebenze amaphupha akhe. Ngelishwa, xa oku kwenzeka ngexesha elingafanelekanga kunokubangela ukulimala.
Ukongezelela, abantu abaneenqanawa banokufumana iindlovu ezinzulu xa beguqulela ekuphumeni (okubizwa ngokuba yi-hypnagogic hallucinations) njengoko ingqondo idala amaphupha ngelixa i-narcoleptic ihlala ivukile.
Nangona kuphela abantu abathathu abaneenqwelo eziphambene neenqanawa baya kuba nezibonakaliso ezine, ezi zichazi ezine ziphawu lwesifo. I-Cataplexy ayiyazi ukuba yenzeke nayiphi na enye ingxaki, ngoko kubakho kuyo kunceda kakhulu ekuboneni i-narcolepsy njengesizathu sezinye iimpawu.
Ukukhawuleza kweNtshontshopsy
I-Narcolepsy yachazwa okokuqala ngudokotela waseFrancis uGean Gelineau ngo-1880. Ngoku kucatshangelwa ukuba kuthintela malunga nabantu abayi-2,000. Iimpawu zokugqithwa kwezidumbu zivame ukuqala kwintsholongwane okanye kwiminyaka eyi-20, kodwa kungenakwenzeka okokuqala kubantwana okanye nakwabadala. Ichaphazela amadoda ngokuqhelekileyo njengabasetyhini.
Kukho ukuhlukahluka kohlanga, njengokuba kungeyona into eqhelekileyo phakathi kwamaYuda ase-Yisrael (kunye nokusabalala kweepesenti ezingama-0.002 kuphela) kwaye ivela ngokuphindaphindiweyo phakathi kweJapan (kunye ne-0.15 ekhulwini). Uphando lwabantu abayi-18,000 kumazwe amahlanu aseYurophu lufumene ubungakanani obuqikelelwayo be-0.047 ekhulwini.
Kukho inxalenye yezofuzo kwi-disorder njengoko i-narcolepsy ingafumaneka ngokuqhelekileyo kwiintsapho zabantu abane-disorder. Nangona kunjalo, indawo leyo ibonakala inendima ebalulekileyo (kuphela ama-25 ekhulwini amawele afanayo aya kuba ne-disorder).
Iingxaki zoNxweme
Ukugqithisileyo kubonakala kuba khona ngenxa yokulahlekelwa kwe-chemical hypocretin kwindawo yengqondo ebizwa ngokuba yi- hypothalamus . Iiseliti zesisongela (okanye i-neurons) kwingqondo exhomekeke kule yikhemikhali ilawula ubuthongo nokuqapha. I-Hypocretin kucingelwa ukuba ivuselele ukuvuvukala kwaye igcine ithoni eqhelekileyo ye-muscle, ngoko kuyaqondakala ukuba ukulahlekelwa kwayo kuya kubangela ubuthathaka obunokubakho ngokubonakalayo obubonakalayo kwi-cataplexy.
Kucingelwa ukuba umzimba omzimba, oqhelekileyo uxanduva lokulwa nokusuleleka, unokuya kumelana ne-neurons ene-hypocretin. Kwiingqungquthela, uphando lubonise ukuba ama-85 ukuya kuma-95 ekhulwini la ma-neurons alahlekile.
Xa la maseli awonakaliswe, kukho rhoqo, ukuguquka okungafanelekanga phakathi kokulala nokuvuka.
Ukunqandwa kwamathambo kungabangelwa zizilonda ezinqabileyo ngaphakathi kwengqondo ephumela ekubeni ngenxa yezidumbu, izibetho okanye ezinye izihlamba.
Ukuxilongwa kunye noPiliso lweNtshontshopsy
Ukuba ukholelwa ukuba unokubandezeleka ngeengxowa zengqungquthela, kubalulekile ukuthetha nodokotela wakho kunye nobungcali bokulala. Emva kokuvavanya nokuhlola ngokucophelela, unokufuna ukufumana ezinye iimvavanyo ukuseka ukuxilongwa kwezidlova . Ngokubanzi, le mvavanyo iya kubandakanya isifundo sokulala ebusuku esibizwa ngokuba yi- polysomnogram kunye nesifundo ngosuku olulandelayo olubizwa ngokuba yi- test multiple latency test (MSLT) .
Ukongezelela, kukho iimvavanyo zelabhoratri (kuquka ukuhlolwa kofuzo). Ukuba izifundo zakho zokulala ziyizinto ezimbi kodwa kusekho ukugxeka okuqinileyo kwiimfucuza, kunokubaluleka ukuvavanya i-cerebrospinal fluid yakho yamachiza orexin (okanye i-hypocretin).
Akukho nonyango yokuphulukana nezidakamizwa, kodwa unyango lunokunceda ukunciphisa ezinye zeempawu. Ukulala ngokwedlulele emini kunganciphisa izikhuthazo ezifana noRitalin , Provigil noNuvigil . Iyeza elithi Xyrem (i-sodium oxybate) lingaphatha kakuhle ukulala kunye ne-cataplexy.
Ukuba unesiphene, kukulungele ukuphonononga ukhetho lwezokwelapha ngogqirha wakho ukuqinisekisa ukuba iyeza elifanelekileyo likhethwe ukulawula iimpawu zakho.
Imithombo
I-American Academy yoLondolozo lweMpilo. "Ukwahlukana ngamazwe ngamazwe okuphazamiseka kokulala: Incwadana yokuxilonga kunye nekhowudi." Wesi-2. 2005.
I-Culebras, A. "Ukuhlaziywa kwi-idiopathic narcolepsy kunye neengxaki ze-narcolepsies." Rev Neurol Dis 2005; 2 (4): 203-310.
Ohayon, MM, et al. "Ubuninzi beempawu zesifo se-narcolepsy kunye nokuxilongwa kwilizwe laseYurophu." Neurology 2002; 58: 1826.
Okun, ML, et al. "Iinkalo zeklinikhi zeengxaki zengqungquthela-zixhamla kwiintlanga." Ukulala ngo- 2002; 25: 27.
UTropy, MJ "I-Narcolepsy." Ukuqhubeka kweeNkalo zokuFunda yonke i-Neurol 2007; 13 (3): 101-114.