Imfazwe EliQumrhu
Ukuvuvukala kukuphendula komzimba kwenzakalo. Ukulandelelana kweziganeko ezinzima, ezidibeneyo zisebenzela ukukhusela umzimba, ekugqibeleni zizisa iiplasma zamaprotheni kunye nama-phagocytes (amaseli egazi amhlophe aphelisa kunye nokutya izinto ezivela ngaphandle nakwezinto ezimbi) kwindawo enobungozi ngenjongo yokuqalisa ukulungiswa kwezicubu.
Kwenzeka njani
Ukulandelelana kweziganeko ezenzeka ngexesha lokuphendula okuvuthayo kuyahluka, kuxhomekeke kuhlobo okanye imbangela yokulimala (oko kukuthi, iibhaktheriya, ukuxhwaleka), indawo yokulimala kunye nomzimba womzimba.
Kwintsholongwane ekhoyo, umzekelo, ukulandelelana kweziganeko kunokushwankathela kumanyathelo a-7:
I-Microbes (ibhaktheriya) ingena emzimbeni.
2 - Imida yegazi encinci iyancuthiswa ukwenzela ukwanda kwegazi.
3 - Kukho ukwanda kwimizimba yeeprotheni.
4 - I-Fluid ishukumisela kwiisishu ezibangela ukuvuvukala.
5 - I-Neutrophils (uhlobo lwegazi elimhlophe) kunye ne-monocytes kamva (olunye uhlobo lweselingo legazi elimhlophe) lihamba ukusuka emithanjeni yegazi ibe yinyama.
6 - Ii-Microbes zitshatyalaliswa kwaye zonakaliswa ngamaseli amhlophe.
7 - Ukulungiswa kwamathambo kuqalisiwe.
Ukuvuvukala kunye nezifo
Kwezinye izifo, inkqubo yokuvuvukala ingabangela nokuba ngaba kungekho bahlaseli bamanye amazwe. Kwizifo ezizimeleyo , umzimba wokhuseleko lomzimba wonakalisa izicubu zaso, njengoko ngokungaziwayo ziyazibona njengento yangaphandle, kwaye ziqhelekile njengento engavamile. Ezinye iintlobo ze-arthritis zibangelwa ukuvuvukala kakubi.
Ukuvutha kunye neArthritis
Igama elithi arthritis ngokwezwi nezwi lithetha ukuvuvukala.
"I-Arth" ibhekisela kwi-joint, kwaye "itis" ibonisa ukuvuvukala. Ezinye iintlobo ze-arthritis ezinxulumene nokuvuvuka zibandakanya:
Umsebenzi ovuthayo
Ingcaciso ecacileyo yeendlela ezibhubisayo ze- rheumatoid arthritis kunye nomsebenzi wokuvuvukala unokufunyanwa ekunqobeni i-Rheumatoid Arthritis: Ukusasaza kwangoko kunye neZonyango nguThomas F Lee, Ph.D.
Xa ukuvuvukala okuhlangeneyo kwenzeka, inani elongeziweyo leeseli kunye nezinto ezivuthayo ngaphakathi kwimbambano edibeneyo, umonakalo we- cartilage , kunye nokuvuvukala kwimbane yokudibanisa. Izibonakaliso zokuvuvukala ngokubambisana ziquka: ubomvu malunga nomxube ochaphazelekayo; ukufudumala kumgca ; intlungu edibeneyo, ukuqina okuhlangeneyo kunye nokuvuvukala. Kukho ukulahleka komsebenzi ohlangeneyo.
Amalungu
Ukuvuvukala kunokuchaphazela izigulane kwizifo ezizimele. Iimpawu zixhomekeke kwinqanaba elichaphazelekayo.
- Ukuvutha kwentliziyo (myocarditis) kunokubangela ukuphefumula okufutshane okanye ukugcinwa kwamanzi.
- Ukuvuvukala kweentso (nephritis) kunokubangela ukungaphumeleli kwezintso okanye uxinzelelo lwegazi oluphezulu.
- Ukuvutha komathumbu omkhulu, obizwa ngokuba yi-colitis, kunokubangela i-cramps kunye nehudo.
Unyango lwe-arthritis
Abantu abanezifo ezidibeneyo ezinezifo zineendlela ezininzi zokonyango :
Mayeza
Ama-analgesics, izidakamizwa ezichasayo kunye namanye amayeza anceda ukulawula ukuvuvukala kunye nentlungu edibeneyo. Izinketho zeziyobisi ziquka:
- NSAID
- Ii-Analgesics (i-Painkillers)
- Corticosteroids
- DMARD
- BRMs / Biologics
Ukuphumla
Imisebenzi eyenza intlungu kufuneka iguqulwe. Kufuneka ukhawuleze imisebenzi enzima kwaye uvumele umzimba wakho ukuba uphumle.
Ukuzivocavoca
Ulwaphulo lomzimba kunye nokuzivocavoca lunceda ukugcina ukuhamba kunye kunye namandla omzimba.
Izinketho zokuphanda
Ukuhlinzwa okuhlangeneyo okanye ezinye iinkqubo zamathambo ekugqibeleni kuyimfuneko ukulungisa umonakalo obangelwa ukuvuvukala okungapheliyo.
Imithombo:
I-Physiology yabantu, ngo-Arthur J. Vander, uJames H. Sherman, uDorothy S. Luciano
Ukuvutha: I-Leukocyte Adhesion Cascade
http://bme.virginia.edu/ley/main.html
Oko Kufuneka Ukwazi Ngobuhlungu. Ikliniki yaseCleveland.