I-Rheumatoid Arthritis nokufa
Ngenye imini, ndakuva umntu esithi, "Hayi, i- rheumatoid arthritis ayikubulali." Andifuni ukungena kwingxoxo emide, eyabandakanyeka ngelo xesha, ndandixoxela ngokungenakuqonda, "Eyona nto ilukhuni ngakumbi kunoko."
I-rheumatoid arthritis ngokuqhelekileyo ingabonwa njengesifo esibulalayo okanye esibulalayo. Enyanisweni, ngokuqhelekileyo kubhekiswa njengesifo esingasigxina, oku kuthetha ukuba uya kuba nexesha lobomi bakho.
Esi sifo sidibene nomngcipheko ophezulu weengxaki ezinokubulawa, nangona kunjalo.
I-rheumatoid arthritis idibene nokunciphisa ixesha lokuphila , inxalenye enkulu ngenxa yeengxaki ezinokukhula. Kuqikelelwa ukuba ixesha lokuphila liyakunqunywa malunga neminyaka eyi-10 kubantu abane-arthritis ye-rheumatoid. Ukucubungula okuqhelekileyo okunxulumene ne-rhyumineid arthritis kucatshangelwa ukuba kubangelwe ngqo ukudala ubomi obancinciweyo, kunye nokudlala indima ekuphakameni umngcipheko wokusuleleka kwintsholongwane, isifo senhliziyo, isifo se-atherosclerosis, kunye nesifo se-metabolic-nayiphi na into ebangela ukuba kufumaneke ukufa kwangaphambili.
Izifo Zeenhliziyo
Ikhonkco phakathi kwe- rheumatoid arthritis kunye nokunyuka kwesifo senhliziyo isifunde kakuhle kwaye iyaqhubeka igxininisa kuphando. Isifo se-Cardiovascular isisona esibangela ukufa phakathi kweplates ne-rheumatoid arthritis. Phantse ama-40 ekhulwini abafayo kwi-rheumatoid arthritis kubangelwa yimicimbi ye-cardiovascular.
Abantu abane-arthritis ye-rheumatoid banomngcipheko ophindwe kabini we-heart attack or stroke xa kuthelekiswa nabantu abangenawo i-rheumatoid arthritis. Umngcipheko ukhula phantse phantse abantu abathathu abane-rheumatoid arthritis iminyaka eli-10 okanye ngaphezulu.
Okuthakazelisayo nangona, iimeko eziqhelekileyo zobungozi zesifo senhliziyo azichazi umfanekiso wonke kubantu abane-rheumatoid arthritis.
Kukho ezinye iipathogenic (izifo ezibangelwa zizifo) ezisebenzisayo, ngokukodwa ezihlobene nokuvuvukala kwenkqubo. Iinkqubo ezinjalo zingabandakanya i-dyslipidemia ye-pro oxidative (amazinga aqhelekanga enamafutha egazini), ukuxhathisa kwe-insulin, ukuxhomekeka kwegazi, amazinga aphezulu e-homocysteine egazini, kunye nemisebenzi ethile yemzimba, njenge-T-cell activation.
Kanti esinye isigulane se-arthritis esibangel 'umdla esichukumisayo-sifo se-rheumatoid asikwazi ukuchaza iintlungu zesifuba kunezo ezingenayo i-rheumatoid arthritis. Baye bathambekele ekuhlaleni ukungena engaziwayo kwe-myocardial infarction (ukuhlaselwa kwintliziyo) okanye ukufa kwegazi ngokukhawuleza.
Syndrome yeMetabolic
I-syndrome ye-Metabolic , iqoqo lezinto zemvelo zengozi yegazi, kuquka ukuxinzeleleka komfutho, ukunyamezela, ukunyamezela kwe-glucose, kunye ne-dyslipidemia kakhulu kakhulu kubantu abane-rheumatoid arthritis. Amakishi aphezulu kunye nokusetyenziswa kwe- glucocorticoids zibhekwa njengengqiqo ye-syndrome ye-metabolic syndrome kulabo abane-rheumatoid arthritis.
Uphononongo olulodwa, olupapashwe ngoJanuwari 2011 lwe- Journal of Rheumatology lubone ukuba ngaba izigulane ze-rheumatoid arthritis ezingenayo imiqondiso ecacileyo yezifo zentliziyo zinobukhulu obuphezulu besifo se-metabolic syndrome.
Isiphetho kukuba abantu abane-rheumatoid arthritis babenomdla ophezulu we-syndrome.
Atherosclerosis
Abantu abane-arthritis ye-rheumatoid banokuxhaphaka kwe-atherosclerosis kunabo abangenawo i-rheumatoid arthritis. I-atherosclerosis kunye ne-rheumatoid arthritis inokwabelana ngeendlela ezininzi ze-pathogenic, kunye nokuvuvukala kwenkqubo kuphakathi kwazo. Kukho nokuba neenkqubo zofuzo zichaphazelekayo. Iziganeko ezizenzekelayo zidlala indima kwi-arthritis ye-rheumatoid kunye ne-atherosclerosis, nayo.
Izifo ezinzulu
Izigulane ze-rheumatoid arthritis ziye zaboniswa ukuba zinobungozi obuninzi bentsholongwane.
Ngokomnye uphando, kwanyatheliswa ngo-Septemba 2002 umxholo weArthritis kunye neRheumatism , owavavanya iziganeko zangaphambili zokusuleleka kwi-arthritis ye-rheumatoid, iminyaka eyongeziweyo, ukubonakaliswa okubonakalayo kwe-rheumatoid arthritis (oko kukuthi, izinto ezingenalo ukubandakanyeka ngokubambisana), ukungaxhatshazi kunye nokusetyenziswa i-corticosteroids yayisisigxina esicacisayo sokusuleleka. Okuthakazelisayo, ngokutsho kweziphumo zophando kwi-Meyi 2013 Journal of Rheumatology isantya sosulelo oluphezulu kwizigulane ze-rheumatoid arthritis sehlile kwiminyaka embalwa edlulileyo.
Ukuxhatshazwa kwesisu
Enye imbangela yokufa ehambelana ne-rheumatoid arthritis yintlungu yesisu . Akuqhelekanga, kodwa kwenzeka isiganeko esibi xa kwenzeka. Abantu abaphathwa nge-glucocorticoids, izidakamizwa ezingabhubhisiyo (non-steroidal anti-inflammatory drugs) (NSAIDS) okanye abanembali ye- diverticulitis basengozini enkulu yokufumana iingxaki zesisu.
> Imithombo:
> Dhawan SS et al. I-rheumatoid arthritis kunye nesifo senhliziyo. Iingxelo zeAtheroclerosis zangoku. 2008 Ngo-Apr; 10 (2): 128-33.
> Rosom S et. al. I-BMC iMisculoskeletal Disorders: I-Metabolic Syndrome kwi-Rheumatoid Arthritis: Uhlolo lokulawula imeko. Aprili 26, 2013.
> Crowson CS et al. Ukwanda kwe-syndrome ye-metabolism ehambisana ne-rheumatoid arthritis kwizigulane ezingenazo izifo zesifo senhliziyo. Journal of Rheumatology Januwari 2011.
> Cavagna l et al. I-atherosclerosis kunye ne-rheumatoid arthritis: ngaphezu kobudlelwane obulula. Abadibanisi bokuvutha. 2012; 2012: 147354. NgoSeptemba 13, 2012.
> NguMhuircheartaigh et al. Iintlobo zentsholongwane enkulu kwi-rheumatoid arthritis. Journal of Rheumatology. Meyi 2013.
> UDoran MF et al. Iziqulatho zokusuleleka kwi-rheumatoid arthritis. Arthritis & Rheumatism. Septemba 2002.
> Curtis JR et al. Isiganeko sesisu esiswini phakathi kwezigulane ze-rheumatoid arthritis. Arthritis & Rheumatism. Fe bruwari 2011.