Ukuba uyazi umntu onesifo se-Alzheimer okanye olunye uhlobo lwesifo sengqondo sokugula, mhlawumbi uye wazibuza ukuba yintoni ebangela ukuba esi sifo sikhule, kwaye ukuba kukho nantoni na ongayenza ukukhusela.
Omnye ummandla oxoxwa ngawo kwaye uxoxwa ngeminyaka ngoku ixinzelelo lwegazi eliphezulu . Kodwa, ngaba uxinzelelo oluphezulu okanye oluphantsi lwegazi luyabangela ukubahluko, okanye ngaba yenye yimiba ephucula kakhulu impilo yakho kodwa ingaxhomekeke kumngcipheko wesifo sengqondo ?
Oko kuthethwa nguPhando
Umxinzelelo ophezulu wegazi uye wajongwa njengengxaki yobungozi be- vascular dementia . Ngoku kutshanje, uphando oluninzi luye lwabandakanya uxinzelelo lwegazi oluphezulu njengengxaki yobungozi be-dementia ngokubanzi-kungabinciphisi umngcipheko we-dementia ye-vascular. Nazi izishwankathelo ezine zezo zifundo:
Uxinzelelo lwegazi oluphezulu luhlanganiswe nokukhubazeka okucokisekileyo kwengqondo.
Olunye uphando lwabandakanya abathathi-918 abathathi-nxaxheba abavavanywa kwisithuba seminyaka eyi-4.7. Abaphandi bafumene ukuba abantu abanexinzelelo lwegazi eliphezulu banokukwazi ukuhlakulela ukukhubazeka okunengqiqo , imeko edla ngokuqhubekayo kwisifo se-Alzheimer. Kuyathakazelisa ukuba olu pho nonongo lufumene ukuba ukukhubazeka okusebenzayo , enye yeempawu zokuphazamiseka kwengqondo engqondweni, yayinokwenzeka ngaphezu kokukhubazeka kwememori , ukuphuhlisa ngegazi eliphezulu.
Uxinzelelo oluphezulu lwegazi luhambelana nokuphuhliswa kwezilonda ezimhlophe kumbilini.
Uphando lwesibini lwabafazi abali-1424 abafumana i- MRIs bafumene ukuba abo abaneengcinezelo zegazi ngaphezu kwe-140/90 ekuqaleni kwesi sifundo babandakanyeka kunye nemilinganiselo ephakamileyo kakhulu yemeko yeengqondo ezimhlophe emva kweminyaka eyisibhozo. Imiba emhlophe yimiba yayiqheleke kakhulu kwi-lobes yangaphambili, kwaye inxulumene nomngcipheko ophezulu wokuba nesifo sengqondo nesifo sengqondo somqondo.
Uxinzelelo lwegazi oluphezulu phakathi kobomi obuhambelanayo neenguqu zengqondo kunye nomngcipheko ophezulu wokugula komqondo kamva.
Ucwaningo lwesithathu lubone ukuba uxinzelelo oluphezulu lwegazi phakathi kobomi lwalunxulumene nomngcipheko ophezulu wokugula kwengqondo kamva kwaye luhambelana nokutshintsha kwindleko yeprotheni ye- beta amyloid engqondweni. Abaphandi bafumanisa ukuba olo tshintsho lwalukho malunga neminyaka eyi-15 ngaphambi kokuphazamiseka kwengqondo, ukubonelela ngobungqina obuninzi bokuthi ukukhuselwa komgudu wokugula ngengqondo kufuneka kugxilwe ngaphambi kokuguga.
Ukungathandabuzeki kwengcinezelo yegazi kuhlanganiswe neenguqu zengqondo eziqhelekileyo kwisifo se-Alzheimer.
Ekugqibeleni, uphando lwesine lufumene ubungqina obuninzi bokudibanisa uxinzelelo lwegazi ukuqonda. Olu pho nonongo lusetyenzise ingqondo yokuhlola ukuhlola abadlali abathathi-nxaxheba abaneminyaka engama-30-89. Abaphandi bafumanisa ukuba abantu abanexinzelelo lwegazi eliphezulu baqokelele iiprotheni ezingaphezulu kwe-beta amyloid ebunzini babo xa kuthelekiswa nalabo abangenawo uxinzelelo lwegazi oluphezulu, ofana nesifundo esasentla. (Ukuhlanganiswa kweprotheni ye-beta amyloid enye yezinto eziphawulekayo zesifo se-Alzheimer.)
Olu cwaningo lukwahluke phakathi kwabantu abaye baphathwa ngamachiza ukulawula uxinzelelo lwegazi kunye nabangenalo. Oko bakufumanisa kukuba ubuchopho babantu abaye baphathwa ngexinzelelo lwegazi eliphezulu-kungekhona nje abo bangenawo uxinzelelo lwegazi olukhuselekileyo-bakhuselwe kwiinguqu ezingqondweni ezingalunganga.
Ngaba Uxinzelelo lwegazi oluphantsi luhlala lungcono?
Kuqhutywe izifundo ezimbalwa ukulinganisa izinga lokuncipha kwengqondo kubantu abanomdemokhwelo wegazi, banengcinezelo yegazi ephantsi kwaye baphathwa nge-antihypertensive (blood pressure lowering). Iziphumo zibonisa ukuba abanye abantu kula mayeza kunye negazi le-systolic Ukufunda uxinzelelo (inombolo ephezulu) engaphantsi kwama-128 yabona ukuhla kwekhawulezi kunokukhawuleza kunokuba abo baphantsi kwengcinezelo yegazi.
Oku kuye kwabuza ukuba njani kwaye nini na ama-antihypertensi anqunyelwe abantu abadala kuneminyaka engama-65, kunye nemibutho ephakamisa isethi ehlukileyo yezikhokelo kubantu abadala asebekhulile.
Uphando olungakumbi lufuneka luqhutyelwe kule ndawo, njengoko kunokwenzeka ukuba ezinye izinto zichaphazela ezi ziphumo.
Amanyathelo alandelayo
Ukuqonda olu lwazi luncedo, kodwa yintoni elandelayo? Nazi iindlela ezintathu ezithathayo zokwenza:
- Yazi ingozi yakho. Ukuba awuqhelanga nokufunda kwegazi, funda rhoqo.
- Buza. Ukuba uxinzelelo lwegazi luphezulu, cela udokotela wakho malunga nokunyanga.
- Thintela. Ukuthintela kwiminyaka emininzi nemibini yobomi kubonakala kubaluleke kakhulu ekunciphiseni umngcipheko we-dementia kwiminyaka kamva. Ukuzilolonga ngokomzimba , umsebenzi weengqondo kunye nokutya okunempilo kunokukwenza umehluko kwimpilo yakho yangoku kunye neyokusasa kwaye bonke badibaniswe nomngcipheko wokuhlaziya ingqondo. Akukaze kukhawuleze ukuqala ukuphila ngendlela enempilo.
> Imithombo:
> American Heart Association. Uxinzelelo lwegazi oluphezulu kunye nezobuchopho beBrains baxhunyiwe. http://newsroom.heart.org/news/high-blood-pressure-and-brain-health-axinked.
> Kuller LH, uMargolis KL, uGaussoin SA, et al. Ulwalamano lwe-Hypertension, Uxinzelelo lweGazi, kunye nokuLawula uxinzelelo lwegazi ngeMpawu eziMhlophe ezingalunganga kwiSifundo seNkcukacha zeMpilo yeNtombi (WHIMS) -I-MRI. Umbhalo we-Clinical Hypertension . 2010; 12 (3): 203-212. i-doi: 10.1111 / j.1751-7176.2009.00234.x
> Mossello E. Uxinzelelo lwegazi oluphantsi kunye nokusetyenziswa kweziyobisi ezingasetyenziswayo. JAMA lwangaphakathi lweMithi . 2015; 175 (4): 578-585. i-doi: 10.1001 / jamainternmed.2014.8164. http://jamanetwork.com/journals/jamainternalmedicine/fullarticle/2173093.
> Reitz C, Tang MX, Manly J, Mayeux R, uLuchsinger JA. Uxinzelelo lwengqondo kunye nomngcipheko wokuKhubazeka koMqondo onzulu. 64 (12). http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2672564/.
> Shah N, Vidal J, Masaki K, et al. I-Midlife Blood Pressure, i-Plasma β-amyloid, kunye neengozi ye-Alzheimer's disease: I-Honolulu yaseAsia. Uxinzelelo lwengqondo (i-Dallas, i-Tex.: 1979). 2012; 59 (4): 780-6. http://www.ncbi.nlm.nih.gov/pubmed/22392902.