Kulungile, iNqanaba lakho le-CRP liPhakamileyo. Ngoku kuthweni?
Ingaba ugqirha wakho walinganisa i-pro-protein ye-protein (CRP) ephezulu, kwaye uyifumene ukuba iphakanyiswe? Le yimeko eqhelekileyo, nangona ininzi iingcali azicebisi ukuba zilinganiselwe ngamazinga e-CRP.
I-CRP yinto engabonakaliyo ye-biomarker ye-inflammation. Oko kukuthi, xa amazinga e-CRP aphakanyisiwe, oko kukubonisa ukuba ukuvuvukala kwenzeka kwindawo ethile emzimbeni.
Ngoko, umzekelo, ukuba unesifo okanye u-bursitis osebenzayo, izinga lakho le-CRP linokuphakama.
Nangona kunjalo, kubonakala ukuba xa amazinga e-CRP ahlala ephakame ngokungapheliyo kubantu abanobuchoko abangenayo imiqondiso yokuvuvukala okusebenzayo, oko kungabonisa ukuba ukuvuvukala okungapheliyo kwemithambo yegazi kubakho. Olu hlobo lwesibalo se-low-grade inflammation luba negalelo kwisifo senhliziyo.
- Funda malunga nokuba nini i-CRP yakho ibalwa .
Ngoku kuthweni?
Kungenzeka ukuba udideke, okanye udideke, ngokufumanisa ukuba i-CRP yakho iphezulu. Ngelishwa, kunokwenzeka ukuba ugqirha wakho uphazamisekile malunga nento oyenzayo ngokulandelayo - kuba "yintoni ongayenza ngokulandelayo" ayilungele ngqo.
Nangona ngoku kusekwa ngokuqinisekileyo ukuba ukuvuvukala kubalulekile ekuncediseni i- atherosclerosis , kwaye oko kuphakanyiswe i-CRP (okuyimakishi yokuvuvukala) kuhambelana nobungozi obuninzi be- coronary artery disease (CAD) , akukho nto ingaziwa ukuba i-CRP ngokwayo inceda ekubangela I-CAD, nokuba ngaba unyango olujoliswe ngokukodwa ekunciphiseni ama-CRP amanqanaba kunciphisa ingozi ye-cardiovascular.
Ngoko, xa i-CRP yakho iphakame umngcipheko wakho wokuphuhlisa i-CAD iphinda iphezulu kunokuba ifanele ibe. Kodwa asikwazi ngokwenene ukuba lunceda ngokwenene ukuthatha amanyathelo ajoliswe ngokukodwa ekunciphiseni amanqanaba akho e-CRP. Kunoko, oko kuyimfuneko ukuba kuthathe onke amathuba okuba unciphise ingozi yakho yomzimba.
Yintoni Okufuneka Yenzeke Ngokulandelayo
Ngoku ukuba uyazi ukuba i-CRP yakho iphakamileyo, kukho imibuzo emibili omele uyibuze.
1) Ziziphi ezinye izinto ezinobungozi?
Amanqanaba e-CRP aphakamileyo ahlala edibene nezinye izinto ezinobungozi zesifo senhliziyo.
Ezi zibandakanya ukutshaya, ukukhuluphala, ukuphila komzimba, ukwanda kwe- cholesterol , uxinzelelo lwegazi kunye nesifo se-metabolic syndrome . Zonke ezi zinto zibeka ingozi kubaluleke kakhulu, kwaye wena kunye nogqirha wakho banako ukufumana bonke abaphantsi kolawulo.
Ngoko, nokuba yini na wena nodokotela wakho unokwenza isigqibo sokwenza malunga ne-CRP ngokwayo, ukuba ne-CRP ephakamileyo yenza kubaluleke nakakhulu ukuba uthathe amanyathelo amanyathelo okunciphisa yonke into enobungozi bomzimba wakho .
2) Ndingayinciphisa njani inqanaba lam CRP?
Nangona kusenakuqinisekiswa ukuba kubaluleke kangakanani ukunciphisa izinga eliphezulu le-CRP ngokwayo, iindlela ezininzi zokunciphisa i-CRP ziye zachongwa:
Izindlela ezingezizo ze-pharmological zokunciphisa i-CRP zibandakanya ukuzivocavoca kwe-aerobic, ukuyeka ukutshaya , ukulahleka kwesisindo kunye nokutya okunentliziyo . Ngamanye amagama, ukuthatha amanyathelo angamaqhinga ukwenza impilo yakho ibe nempilo iya kuba negalelo le-CRP elincinci.
Ukusetyenziswa kweziyobisi kunokunciphisa i-CRP . ** Izitatimende ** zinciphisa amanqanaba e-CRP ngokukhawuleza (13 ukuya kuma-50%,) ngokutsho kwezilingo ezininzi zeklinikhi.
I-Lipitor (i-atorvastatin), i-Mevacor (i-lovastatin), i-Pravachol (i-pravastatin), iCrestor (rosuvastatin) kunye neZocor (simvastatin) bonke baboniswe ukuzisa amanqanaba e-CRP kwaye babonise ubungqina bokunciphisa ingozi yomzimba nge-CRP (ngokuchasene ne-cholesterol) . Kwakhona, isilingo seJUPITER sibonise ngokuqinisekileyo ukuba kwizigulane ezinezinga eliphezulu ze-CRP kodwa "eziqhelekileyo" ze-cholesterol, iCrestor kakhulu kwaye inciphise kakhulu ingozi yomzimba.
Nangona i- aspirin inganciphisi amanqanaba e-CRP, abantu abanamazinga aphezulu e-CRP bafumana inzuzo yokunciphisa ingozi kwi-aspirin kunezo eziqhelekileyo ze-CRP.
Amanqanaba e-CRP aphakamileyo angabetha isilinganisi ngokunyanga kweprophylactic yonyango lwe-aspirin kwabanye.
Funda ngokubanzi malunga nobani okufanele athathe i-prophylactic aspirin .
ILizwi
Akusaziwa nokuba i-CRP ngokwayo iyandisa ingozi yomzimba, okanye ingaba ibonisa nje ukulimala kwamathambo kunye nokuvuvukala okubangelwa kwezinye izinto ezinobungozi. Ngoko ukuba amanqanaba akho e-CRP aphakanyisiwe, kufuneka uthabathe loo nto njengesibonakaliso esibalulekileyo sokuba lixesha lokufumana ingxaki malunga nokunciphisa yonke into enobungozi benhliziyo yakho ngokusebenzisa, ukubhema, ukulahlekelwa ubunzima, ukujonga ukutya kwakho, nokulawula uxinzelelo lwegazi.
Nangona kunjalo, ngoku kubonakala ngokucacileyo ukuba ukusetyenziswa kwezidakamizwa ze-statin kunokunciphisa kakhulu umngcipheko wokuhlaselwa kwintliziyo kunye nokushayiswa kwezigulane kwizigulane ezibonakala ziphilileyo.
Ukuba unamazinga aphezulu e-CRP, ingakumbi ukuba unomnye okanye ngaphezulu kwimiba yengozi yesifo senhliziyo, kufuneka uxoxe ngokukhetha ukuthatha izidakamizwa ze-statin ugqirha wakho.
> Imithombo:
Izinto ezinobungozi bokubambisana Ukubambisana, iKaptoge S, Di Angelantonio E, et al. Iiprotheyini ezisetyenziswayo zeC-Concentration and Risk of Coronary Heart Disease, Stroke, kunye nokufa: Umntu ochaphazelekayo u-Meta-analysis. Lancet 2010; 375: 132.
> Hingorani AD, Sofat R, Morris RW, et al. Ngaba Kubalulekile Ukulinganisa okanye Ukunciphisa Iprotheni Esebenzayo Kwi-Abantu Ejongene Nezifo Zeengqondo? I-Eur Heart J 2012; 33: 2258.
> Ridker PM, uDanelson E, uFonseca FA et al. I-Rosuvastatin ekukhuseleni iziganeko ze-Vascular kwiMadoda nabasetyhini abaneProtein ephakamileyo ye-C. I-Engl J Med 2008; INGXELO: 10.1056 / NEJMoa0807646.
> Sever PS, Poulter NR, Chang CL, et al. Ukuvavanywa kweProtein e-C esebenzayo phambi koNyango kunye noNyango oluPhezulu njenge-Predictor of Benefit from Atorvastatin: Imiba evela kwiiNgxelo zeCardiac Cardiac Iziphumo. I-Eur Heart J 2012; 33: 486.