I-atherosclerosis iyisifo esingapheliyo, esiqhubekayo apho iiplati zakha kwiindonga zeetriyri .
Ezi zihlabayi zenziwe ngama-deposits ye-cholesterol kunye nezinye iipilisi, i-calcium, kunye neeseli ezinkulu ezivuthayo ezibizwa ngokuba yi-macrophages. Emva kokuba i-plaque ikhona kwi-artery, inokubangela iintlobo ezininzi zeengxaki.
Okokuqala, iiplati ziyakwazi ukuqhubela umthamo, ekugqibeleni kubangele ukuphazamiseka okwexeshana okanye okupheleleyo ukuhamba kwegazi.
U-angina ozinzileyo ngumzekelo weemeko zonyango eziveliswa yiplanka eqhubekayo.
Okwesibini, iiplates zingabangela i-thrombosis. I-thrombosis ye-arterial iyenzeka xa i-plaque iphelile ngokukhawuleza, kubangele i-thrombus (i-clot yegazi) yokwenza. I-thrombosis ingakhokelela ekutshatyalaliswa ngokukhawuleza komthamo. Enye ingxaki yonyango eveliswa ngokuphulwa kwamathambo yi -coronary syndrome (ACS) .
Okwesithathu, iiplati zingenza buthathaka udonga lomthamo obangela ukuba i-ballooning ngaphandle komthamo ibe yinto ebizwa ngokuba ne-aneurysm. I-rupturing ye-aneurysm ivelisa ukuphuma kwamanzi kwangaphakathi. I- aortic aneurysm ephuhliweyo ngumzekelo wesiganeko esinjalo.
Ezinye izifo zonyango eziqhelekileyo ezibangelwa yi-atherosclerosis zibandakanya isifo , isifo se-artery kunye nesifo sesifo.
Izizathu
Isiseko esiyintloko esibangela ukuba i-atherosclerosis ayinakunikwa ngokupheleleyo.
Nangona kunjalo, kukho izinto ezininzi ezibangela ukuba i-atherosclerosis ichongwe, kuquka:
- I-Genetic predisposition - i-atherosclerosis ihamba kakuhle kwiintsapho. Nabani na osondelene naye (abazali, sibs, u-uncle kunye nonina) baye bafumana i-atherosclerosis kufuneka bathathe onke amathuba okunciphisa iimeko zabo zobungozi.
- I-cholesterol engaqhelekanga - amazinga aphezulu egazi ye-LDL ye-cholesterol kunye namazinga aphantsi ye-cholesterol ye-HDL inxulumene ne-atherosclerosis.
- U xinzelelo
- Ukutshaya
- Indlela yokuphila
- Ukunyameka, ngakumbi ukukhuluphala kwesisu
- Sikashukela
Kwiinkcubeko zaseNtshona, kwanabuntwaneni kunye nemibhobho ebushushu ibonisa ukuba utshintsho lwe-atherosclerosis lwangaphambili. I-atherosclerosis iqala njengesigqithiso, isifo esiqhubekayo esiya kuphuhliswa ngaphezu kwexesha leminyaka ngaphambi kokuqala ukuvelisa iimpawu.
Arterial Affected
I-atherosclerosis ivame ukuchaphazela i- coronary arteries , ekhokelela kwi-angina kunye ne- myocardial infarction (ukuhlasela kwentliziyo); ukujikelezwa kwe-cerebrovascular (ubuchopho beengqondo), obangela ukubetha ; iidrare ze-renal, ezikhokelela kwizifo zesifo; i-aorta, ekhokelela kwi-aortic aneurysm; kunye nemithambo yegazi yeengalo kunye (ngokukodwa) imilenze, ekhokelela kwisifo se-artery kunye nesigqabiso, isilonda, ukuguquka kwesikhumba, kunye nokuphulukisa.
EUnited States, i-atherosclerosis ibangela ukufa nokukhubazeka ngaphezu kwesinye isifo.
Unyango
Oogqirha bachithe ixesha elininzi lokuphatha iziphumo ze-atherosclerosis-ukuhlasela kwentliziyo, ukubetha, ukuhluleka kwezintso, isifo se-artery, njl. Ngoko unyango lukhona kwizinto ezinjalo. Kodwa unyango luba nzima, lubiza, luyingozi, kwaye / okanye luyingozi.
Kude, "unyango" olungcono kakhulu lwe-atherosclerosis kukuba wenze konke onokukwazi ukukhusela i-atherosclerosis ukusuka kwindawo yokuqala, okanye ukuba sele ikhona, ukuthatha yonke imilinganiselo ekhoyo ukuze uqhubeke nokuqhubela phambili.
Ezi nyathelo ziquka ukutya ukutya okunempilo, ukufumana umzimba omningi, ukugcina ubunzima bakho kwizinga elimkelekileyo, ukungafuni ukutshaya nokuqinisekisa ukuba uxinzelelo lwegazi luluhlu oluhle.
Imithombo:
Unamandla, JP, Malcom, GT, McMahan, CA, et al. Ubuninzi kunye nobukhulu be-atherosclerosis kubantu abaselula nabaselula. Impembelelo yokuthintela kwiziphumo ze-pathobiological of atherosclerosis ekufundweni kwentsha. JAMA; 281: 727.
Libby P, Ridker PM, uHansson GK. Inkqubela kunye nemingeni ekuguquleleni i-biology ye-atherosclerosis. Nature 2011; 473: 317.