Ekubeni kunemiphumo emibi ye-niacin ehambelana nokuthatha iimveliso ze-nicotinic acid, ungase ufune ukusebenzisa i-niacin engeyiyo, okanye u-niacin ukhululekile, ukunciphisa i-cholesterol yakho.
IiFomu zeNiacin
I-Niacin , okanye i-vitamin B-3, isongezelelo esaziwa ngokuba namandla okunciphisa i-cholesterol kunye nokukhusela isifo senhliziyo. Kukho iintlobo ezintathu eziyinhloko ze-niacin ezikhoyo kwimarike: i-nicotinic acid, i-nicotinamide, ne-inositol hexaniacinate.
Zonke ezi zintlobo ze-niacin zifumaneka ngaphezu kwe-counter-counter, ngokuzimeleyo okanye zifakwe kwi-multivitamin, ngexabiso elinganayo.
I-Nicotinic acid yindlela yokwenza uphando oluninzi ngenxa yokukwazi ukunciphisa i-cholesterol. Enyanisweni, i-nicotinic acid iboniswe ukuba ichaphazele zonke iinkalo zeprofayili yakho yepilid : inokuphakamisa i- lipoproteins ephezulu ("okuhle" i-cholesterol, i-HDL) kunye neepoprotein (low "i-cholesterol" embi, i-LDL) kunye ne- triglycerides .
Nangona i-nicotinic acid ichaphazela zonke iipaliti zeprofayili yakho, ikwaqatshelwa ngenxa yemiphumo emibi yayo, equka ukubetha, ukutshiza kunye nokutshisa okutshisa. Ezi ziphumo zempembelelo zingenakuze zinyanzeliswe kwaye zizona zizathu eziqhelekileyo zokusebenzisa i-nicotinic acid.
I-Non-Flush Niacin
I-nicin ye-nicotinic ye-flats-free or non-flush yindlela ye-nicotinic acid eyaziwayo njenge-inositol hexaniacinate. I-niacin engenawo umbane ifumana igama layo ekubeni likwazi ukunciphisa iziphumo ezibi njengefuthe ezibonakalayo nezinye iindiac.
Ngelishwa, ayikho into eyaziwayo nge-niacin engenamanzi, kwaye abaphandi bafumanisa ukuba ifomu elisebenzayo lingaze lingene egazini. Ngako oko, akunakwenzeka ukuba i-niacin engenamanzi ayinciphisa i-cholesterol.
I-niacin engenamaphunga iqukethe iimachileli eziyi-6 ze-niacin ezidibene kunye ne-chemical inositol.
Kucetyiswa ukuba, emzimbeni, le michiza iphulwe phantsi ibe yi-nicotinic acid kwaye ingena kwigazi. Ekubeni le nkqubo ithatha ixesha elide ukuba lize lenzeke, kucingelwa ukuba le yeso sizathu sempembelelo yaso. Nangona kunjalo, ukuba inani eliphezulu le-niacin litshiswa, ungasenokuba nemiphumo emibi ye-niacin.
I-niacin engenawo umbane iyakwazi ukuphucula imithambo yegazi kwaye isetyenziswe unyango lwezifo, ezifana nesifo sikaRaynaud . Iingcamango zokusebenzisa i-nicotinic acid zininzi; Nangona kunjalo, uphando oluhlola ukuphumelela kwe-inositol hexaniacinate yedwa ekunciphiseni amazinga e-cholesterol ambalwa.
Enyanisweni, kuye kwaba neengxoxo malunga nokuba i-niacin ayiyikukhupha imilinganiselo ye- cholesterol ayizange ibe neengxelo ezaneleyo zokuxhasa okanye ukukhanyela oku. Olunye uphando luye lwabonisa ukuba ukuya kuma-2,400 mg ye-niacin engenamhlanjesi ngosuku (kwiisahlulo ezihlukeneyo) kuyadingeka ukunciphisa amazinga e-cholesterol, kanti ezinye iingcaphephe zibonise ukuba i-niacin engenawo umthamo awunasiphumo ekunciphiseni i-cholesterol.
Olunye uvavanyo oluphawulekayo oluhlola iindlela ezahlukeneyo ze-niacin lilinganisa ixabiso le-nicotinic acid, i-niacin eyanciphisa i-cholesterol, ifumaneka egazini emva kokuba imveliso ifakiwe.
Uphando lwafumanisa ukuba emva kokuba i-1.6 gram ye-inositol hexaniacinate ithathwe, kuphela i-0.6 micromoles / L ye-nicotinic acid yafunyanwa kwigazi.
Ukuthelekisa, ukuthatha igramu enye ye-nicotinic acid ngokukhawuleza kwaphumela kuma-micromoles angu-240 / L afunyenwe egazini xa kuthatha iigramu ezimbini zokukhululwa kwe-acidic nicotinic ekhuseleyo yenze ukuba kuphakathi kwe-31 micromoles / L efunyenwe egazini, zombini zanele ukwehlisa i-cholesterol.
Ngoko, ngeyona nicotinic encinci kwigazi elibonwe kulolu cwaningo, kunye nokungabikho kobubungqina obubonwe kwezinye iifundo, akungabazeki ukuba i-niacin engenakucala iyasebenza ekunciphiseni i-cholesterol.
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