Indlela i-pathogenesis kunye ne-pathophysiology eyazisa ngayo unyango
I-Pathophysiology ligama esasilisebenzisa ukuchaza indlela isifo eshintsha ngayo umsebenzi oqhelekileyo womzimba. Ivela kwisiGrike isiqalo se- pathos esithetha "ukubandezeleka" kwaye ingcambu ye- phusiologia ithetha "ifilosofi yendalo."
Ngokumalunga nesimo esinjenge-asthma, siza kuchaza iindlela ezithinta ngayo isifo somsebenzi oqhelekileyo wemiphunga, njengale:
- Indlela esi sifo esibangele ukuvuvukala okungapheliyo kweendinyana zomoya
- Indlela esi sifo esibangelwa ngayo i- bronchoconstriction , ukuqiniswa kwezihlunu ezijikelezayo kwiindinyana zomoya
Ngokwahlukileyo, i-pathogenesis (i- genesis ithetha "imvelaphi") ichaza apho isifo siqala khona kunye neenketyambo zeziganeko ezenzeka kweso sifo.
Ngomxholo wesifo se-asthma, i-pathogenesis ichaza indlela umzimba wokuzivikela ngayo osabela ngokungaqhelekanga kwi-stimuli ebangela ukuvuvukala okungapheliyo kunye ne-bronchoconstriction ebangela ukuqina nokuqina kweendlela ezibangele ukuqhubela phambili ukuphefumula ukudala umonakalo kwezinye iindawo zomzimba, ezifana nesimo senhliziyo .
Ngaloo ndlela, i-pathophysiology ichaza indlela isifo esitshintsha ngayo indlela yokwenza umzimba xa i-pathogenesis ichaza indlela eso sifo siphucula ngayo.
Ukuqonda ukuvuvukala okungapheliyo
Abantu abanesifo se-asthma bayaziwa ukuba baxhomekeke kwizinto esizibiza ngokuba ngababangela .
Oko kuthetha ukuthini ukuba imithi ethile, njengothuli okanye impova, ayibonakali ngokungalunganga ukuba isistim somzimba sikhuseleke.
Ekubangela impendulo, umzimba uya kukhupha iikhemikhali ezivuthayo njengenxalenye yesistim somzimba. Ezi khemikhali ziya kuthi, phakathi kwezinye izinto, zenze iinqanawa ezincinci zegazi zikhulise ukwenzela ukuba amangqingili omzimba okukhusela angakhukhumeza indawo yokutheleleka.
Xa oku kwenzeka emiphakeni, izicubu ngokwazo ziya kuqala zivule kwaye zivutha.
Ngelo xesha, umzimba uya kuvelisa i-muscus ekhuselekileyo njengenqanda yokukhusela ngokusongela ukungabikho kokusongela, ukuvalela umoya kunye nokuphefumula.
Ukuthukuthela okungapheliyo kunokukhokelela kwinkqubo ebizwa ngokuba yi-airway remodeling apho iindonga zeendinyana zomoya ziqala ukunqanda kwaye zizinzima, iimbumba ziqala ukwandisa, kwaye inethiwekhi yemithambo yegazi ihamba ngokungaqhelekanga. Ezi zigugu zenguqu kwimiphunga zibhekwa zingenakwenzeka kwaye ziyahambelana nokugqithisa kweempawu.
Ukuqonda iBronchoconstriction
Ngexesha lokuhlaselwa kwesifuba se-asthma, isimiso somzimba womzimba siphendula ngendlela engavumelekanga ukuba senze i-stimuli. Oku kubangela ukukhululwa kweembamamine kunye nezinye izinto ezingabonakaliyo ukuba izigatshana ze-airway zenze isivumelwano, zithintele ukungena kwe-oksijini. Le nkqubo, ebizwa ngokuba yi-bronchospasm, iyanzima ngakumbi ukukhutshwa kweendinyana nge-mucus, nto leyo ibangele ukuphefumula kokubili kunye nokukhwehlela okungapheliyo (ukukhulula i-mucus).
I-bronchospasm ngokuqhelekileyo ihlala enye ukuya kwiiyure ezimbini. Kwezinye iimeko, ke, isiganeko sokuqala singaphambi kokuhlaselwa okulandelayo emva kweeyure ezintathu ukuya kwezi-12 kamva.
Indlela iPathophysiology kunye nePathogenesis ikwazisa ngayo unyango lwe-Asthma Treatment
Ngokuqonda i-pathophysiology yesifo, sinokufumana izixhobo ezifunekayo ukuze kulungiswe impendulo okanye ukukhusela ukuba kwenzeke.
Ngokuqonda i-pathogenesis yesifo, sinokufumana iindlela zokuziphepha, ukuyiguqula, ukuyiphilisa, okanye ukuthintela ekuqhubekeni kwikhosi elilindelekileyo.
Yaye yinto ebalulekileyo yokukhumbula nge-asthma: ukuba ngelixa singenayo indlela yokuyiphilisa, siyazi indlela yokulawula iimpawu zayo kunye nokucotha (ukuba ayigcinanga ngokupheleleyo) ukuqhubeka kwayo. Ekugqibeleni, isikolo sesifo asiphepheki kwaye sinokutshintshwa ngokusetyenziswa okufanelekileyo kweyeza kunye nokuphathwa kweendlela zokuphila. Ezi ziquka:
- Ukuthatha amayeza akho njengoko kuchaziwe
- Ukugcina i-inhaler yakho yokusindisa kufuphi
- Ukuphepha ukukhupha okubangela ukuhlaselwa
- Ukugonywa ngokuchasene nomkhuhlane okanye i-pneumonia
- Ukujongana nokukhetha indlela yokuphila ukuphucula umsebenzi wamaphaphu, kubandakanya ukutya kunye nokuzilolonga
- Ukutyelela ugqirha wakho rhoqo ukujonga impilo yakho yokuphefumula kwaye uqinisekise ukuba unyango lwakho luchanekile.
Ekugqibeleni, isikolo sesifo sakho sikhulu kwizandla zakho. Ngokuqonda iinkqubo apho iimpawu ze-astmma zenzeka kwaye ziba nzima, ungathatha amanyathelo afunekayo ukukhusela impilo yakho yokuphefumula ngokuhamba kwesikhathi.
> Umthombo:
> Lynn, S. kunye noKushto-Reese, K. " Ukuqonda i-asthma pathophysiology , ukuxilongwa, kunye nokuphathwa." Ubuhlengikazi baseMerika namhlanje. 2015; 10 (7): 49-51.