Ipropofol , edayiswa phantsi kwegama legama elithi Diprivan, iqukethe i-lecithin yeqanda kunye neoli ye-soya . Ngoko ke, oogqirha abaninzi baye bakhathazeka ukuba kungenakho ukukhuseleka kubantu abanomdla wokutya kwabo, ngokukodwa ukwanda kweqanda.
Izifundo zibonise ukuba ipropofol ibonakala ikhuselekile kuninzi lwabantu abaphikisayo kumaqanda. Nangona kunjalo, kukho iingxelo zecala elizimeleyo zempembelelo ezinzima eziye zenzeka emva kokusetyenziswa kweziyobisi kubantu abanokuba ne- anaphylactic allergies .
Ukusetyenziswa kwepropofol kwiAnesthesia
Ipropofol yintsholongwane enamandla yenza ukuba uphumule kwaye ulale ngokunciphisa umsebenzi wengqondo yakho kunye nenkqubo yesifo. Unikwa ngenaliti emthanjeni wakho, kwaye xa ufumana oko, mhlawumbi awuyi kukukhumbula nto - uya kulala ngokukhawuleza.
Isilwanyana sisetyenzisiwe kwiinqununu zokunyamekela ezinzulu ukuze zidibanise abantu abakwiindawo zokuphucula umoya, kunye namagumbi aphuthumayo njenge- anesthesia yeenkqubo ezifutshane, ezibuhlungu. Ayisebenzisi ngaphandle kwesibhedlele, njengoko kuyingozi kakhulu ngaphandle kokubeka iliso nokuqeqesha. Enyanisweni, ipropofol yayiyilisi elalibulala umculi uMichael Jackson.
I-Propofol ibe yinto yezilwanyana ezikhethiweyo zokusebenzisa i-anesthesiologists, zombini kwiimeko apho isigulane sidinga kuphela ukulala ngenxa yemizuzu embalwa (umzekelo, ukuba nenkqubo ebuhlungu eyenziwa, njengokumisa kwakhona ihlombe elixubileyo) nakwiimeko apho i-aneshesia Iyafuneka.
Kufuna ukubeka iliso ngokugqithiseleyo kuba kunokukuyeka ukuphefumla.
I-Propofol ne-Egg Allerggies
Njengoko kuchazwe ngasentla, ipropofol iquka i-lecithin yeqanda kwindlela yakhe yangoku. I-Lecithin yintlobo yamafutha, kungekhona iprotheni, kwaye ezininzi iintlobo zeeqanda ziquka iprotheni, kungekhona amanqatha kumaqanda.
Nangona kunjalo, ifowuni yepropofol isichaza ukuba abantu abanexholongwane naluphi na isilathisi sezilwanyana akufanele basebenzise amayeza, kwaye kukho iingxelo ezininzi zeempendulo eziye zenzeka ngenxa yepropofol.
Oko kuthethwa, oogqirha baye bajonga ukusetyenziswa kwepropofol kubantu abaphikisayo kumaqanda kwaye baye bafumanisa ukuba kubonakala ngathi ikhuselekile.
Olunye uphando lwama-Australia lwaluhlolisisa iimeko ezingama-28 abantwana abaneqanda lokunyuka kweqanda, abaye bafumana i-propofol engama-43 phakathi kwabo. Abantwana babini babenomlando we-anaphylactic ukusabela kumaqanda. Kwakukho umntu ongenayo i-anaphylactic yokusabela kumntwana oneminyaka eyisixhenxe owayengumntwana onamaqanda, kunye nobisi , iisuthi kunye nesame . Ukuphendula kwenzeka emva kwemizuzu engama-15 emva kokusetyenziswa kwepropofol, kwaye le nkwenkwe yasabela kwimeko yokuvavanya kwesikhumba kunye nepropofol. Ababhali baphetha ngokuthi ipropofol inokukhuseleka kuninzi kubantu abanamaqanda.
Olunye uphando lubhekise kwiimeko apho abantu abadala abanesifo esihle samakhanda amaqanda, i-soy okanye i-peanuts yayinepropofol elawulwayo. Ayifumananga naluphi na unxibelelwano phakathi kweempembelelo eziphazamisayo kunye nepropofol.
Ngaphantsi
Ngokusekelwe kwezi zifundo zophando, ipropofol ibonakala ikhuselekile kuninzi lwabantu abaneqanda elithintekayo. Nangona kunjalo, kufuneka uxoxe nodokotela wakho malunga naloo nto xa unamaqanda amaqanda, ngokukodwa ukuba uye waba neempembelelo ze-anaphylactic kumaqanda esikhathini esidlulileyo. Ngokuxhomekeke kubukhali beqanda lakho, udokotela wakho unokuncoma enye i-anesthesia.
Imithombo:
Asserhøj LL et al. Akukho ubungqina bokuphikisana nokusetyenziswa kwepropofol kubantu abadala abaqhekezayo kwiqanda, i-soy okanye i-peanut. IBritish Journal of Anesthesia. 2016 Jan; 116 (1): 77-82.
I-Diprivan 1%. I-Diprivan Monograph eyenzelwe ngumenzi weziyobisi AstraZeneca. Agasti, 2005.
I-Hepner, iDL, MD kunye ne-MC Castells, MD PhD. I-Anaphylaxis Ngethuba lexesha eliPerioperative. IAnesthesia kunye ne-Analgesia. Novemba 2003. Vol. 97 No. 5.
Hofer K et al. I-anaphylaxis enokufumaneka emva kwepropofol kumntwana onesifo sokutya. Amanqaku e-Pharmacotherapy. 37 (3): 398-401, 2003.
Murphy A et al. Ukuphendulwa kwe-allergen kwipropofol kwi-egg-childrenergic children. Anesthesia & Analgesia. 2011 Julayi; 113 (1): 140-4.