I-Anti-Androgenic Medication Inokukunceda
Ngokuqhelekileyo kuthengiswa phantsi kwegama lohlobo lweproscar kunye nePropecia, i-Finasteride yile nyanga esetyenziswa rhoqo ekuphatheni ukukhula kweprotate ebonakalayo kunye Ukuqhafaza kwendoda kwindoda. Ngamanye amaxesha i-finasteride imiselwe njengenkomfa yokulwa ne-androgenic yabasetyhini abane- polycystic ovary syndrome (i-PCOS) ababonisa ukukhula koboya bezinwele ezingafunekiyo ebusweni babo, esifubeni, okanye ngasemva (i- hirsutism ).
Indlela i-Finasteride ithinta ngayo ama-PCOS Symptoms
I-Finasteride isebenza ngokuthintela i-androgens, eyiqela lamahomoni adlala indima kwiimpawu zesintu kunye nomsebenzi wokuzala. Xa i-orrogens kwiintloko zezinwele zivaliwe, ukulahlekelwa kweenwele ezinxulumene ne-PCOS kunye ne-hirsutism kuncipha.
I-70-80% yabasetyhini abanee-orrogens ezingaphezu kwemali babonisa i-hirsutism. I-Androgens ikwandisa izinga lokukhula kweenwele kwaye liguqule elifutshane, elihle, elikhanyayo, iincinci zentombazane (i- vellus izinwele ) ukuya kwiinwele ezinqamle, ezide, kunye ezimnyama.
Xa i-androgens iyancishiswa, ukunyuka kweenwele ezintsha kuncitshiswa kwaye ukukhula kweenwele eziphelileyo zikhoyo. Izinwele zikhula ngamaxesha ahlukeneyo kwaye isigaba sokukhula siyahluka ngokwemimandla yomzimba, ngokukhula okupheleleyo, lo mjikelo wokukhula ubuncinane malunga neenyanga ezine zobunwele bomzimba. Yingakho kukhuthazwa ukuba unike unyango lwe-hormone ngaphezu kweenyanga ezili-6 ukuze usebenze ngokupheleleyo.
Kwabaninzi abasetyhini, iimpawu ze-androgenic zi-hirsutism, kodwa kwabanye, ingaba yintsimbi okanye i- alopecia .
Abafazi abaninzi banama-hirsutism kunye nama-acne kunye nezikhalazo ezimbalwa ze-acne, i-hirsutism, ne-alopecia. Labo abanama-acne bavame ukuzama ukusebenzisa unyango lwamayeza kunye nemilomo yomlomo njengamayeza okulwa namagciwane, kodwa i-acne ibuye ibuye emva kokuyeka unyango.
I-Finasteride isebenza njani
I-Finasteride inqanda intetho ye-enzyme ye-2, i-5-alpha reductase.
Le enzyme ilawula ukuveliswa kwe-dihydrotestosterone (DHT) eboniswe ukuba inokulimaza kwiintlobo zezinwele. Ukuthatha amayeza kuye kwaboniswa ukunciphisa amazinga e-DHT ngama-70%.
Inani eliphakanyisiweyo lomlinganiselo liyahluka ukusuka kumntu ukuya kumntu kunye namayeza a-2.5mg okanye ama-5mg ngosuku. Kucelwa ulandele imiyalelo enikwe ngugqirha wakho.
Iimiphumo zangaphandle
Nceda uqaphele ugqirha wakho nayiphina imiphumo oyingozi. Ezinye iziphumo zecala ezichazwe ngokuqhelekileyo zezi ziyiyo:
- Ukunciphisa umnqweno wesini
- Ubuhlungu kwiibele
- Iimpawu zempembelelo ezichaphazelayo zibandakanya imihlathi okanye enye indlela yokuphendula ngesikhumba kunye / okanye ukuphefumula ubunzima
Izongezelo zeTestosterone zingakwazi ukusebenzisana ne-finasteride. Nceda uvumele ugqirha wakho ukuba wazi ukuthatha nawaphi na amanye amayeza.
Ukukhulelwa kunye neFinasteride
Ngelixa iFfinasteride inexabiso eliphantsi leempembelelo ezinxulumene nalo, isilwanyana sinomphumela wesisu kumntwana wesisu.
Kubalulekile ukuba ungakhulelwa ngelixa uthatha i-finasteride, ngenxa yobungozi obunokuba ngumntwana okhulayo. Qinisekisa ukusebenzisa ifom efanelekileyo yokulawulwa kokuzalwa ngelixa uthatha i-finasteride.
Kwakhona kubalulekile ukuba abafazi abakhulelweyo bangayisebenzisi le mayeza.
Imithombo:
UAzziz R. Uvavanyo kunye noLawulo lweHirsutism. I-Obstet. Gynecol. 101, 995-1007 (2003).
Dallob AL, uSadick NS, Unger W et al. Impembelelo ye-Finasteride, i-5 Creductase Inhibitor kwi-Scalp Skin, i-Testosterone kunye ne-Dihydrotestosterone Iingqwalaselo zam izigulane ezine-Baldness yamadoda. J. Clin. Endocrinol. Metab. 79, 703-706 (1994).
ULumachi F, uRondinone R. Ukusetyenziswa kwe-Acetate ye-Cyproterone, i-Finasteride kunye ne-Spironolactone yokuphatha i-Idiopathic Hirsutism. Fertil. Steril. 79, 942-94 (2003).