Ukuba unomdlavuza wegazi onjenge- leukemia okanye i- lymphoma , kuyinto engokwemvelo ukuba uveze ubuninzi bexinzelelo okanye uxinzelelo. Ezi mvakalelo zingabangela ukukhathazeka ngexesha elizayo, iingxaki zezemali okanye zeentsapho, okanye imiba yemihla ngemihla njengokungena kwisikhungo somhlaza okanye ukukhumbula ukuthatha amayeza. Kungakhathaliseki ukuba yiyiphi imbangela, uxinzelelo lunokuba nefuthe kwimpilo yakho mhlawumbi nangomphumo wonyango lwakho.
Ngaba Ingcinezelo Inokubangela ICarcer?
Kule minyaka, ezininzi izifundo zenzululwazi ziye zazama ukufumanisa ukuba uxinzelelo lunokubangela umdlavuza, okanye ludale ukuba lukhule ngokukhawuleza. Xa umzimba uphantsi koxinzelelo, ukhupha i-hormone ezixinzelelekileyo ezifana ne-cortisol kunye ne-adrenaline-hormones ezinokuthi, ekuhambeni kwexesha, yenza ukuba isistim sakho sokuzivikela sikhatyathelwe (akukho msebenzi.) Kungenxa yoko unokubona ukuba ngamanye amaxesha ebomini bakho xa uphantsi kwengcinezelo eninzi, njengesihlandlo esikolweni okanye nje ngaphambi kokuba udliwano-ndlebe lomsebenzi, wehla ngesifo. Iingcali zenzululwazi zikholelwa ukuba ukuxhatshazwa kwenkqubo yokuzikhusela komzimba kungenza umzimba ube neengcingo ezinjenge-lymphoma.
Ngoku kutshanje, abaphandi baye baqalisa ukuphanda ubudlelwane phakathi koxinzelelo kunye nemfuza. Baye bafumanisa ukuba iimeko ezixinzelelekileyo zingenza ukuba izakhi ezithile zegciwane ziqaliswe kwaye ezinye zivaliwe, ezikhokelela ekubeni utshintsho olunokuchaphazela ukukhula komhlaza.
Ngokomzekelo, inzululwazi inqume ukuba i-hormone yokucindezeleka i-cortisol inokutshintsha i-genetics yomzimba kwaye iphazamise amandla okugonywa kwamagciwane ukuba enze umsebenzi wabo.
Ukugxininiswa kunye neziphumo kubantu abaneCarcer
Olunye uphando olupapashwe kwiYunivesithi yase-Ohio State ngoSeptemba 2010 uphando malunga nefuthe loxinzelelo, kokubili ngokwengqondo nangokwenyama, kwiziphumo zonyango lomhlaza.
Abaphandi baye bafumanisa ukuba uxinzelelo emzimbeni, kubandakanywa nokuzikhandla okukhulu, kusebenze iprotheni ebizwa ngokuba yinto yokushisa ukushisa-1 evulela enye iprotheni ebizwa ngeHsp27. Ukuba khona kwe-Hsp27 kuye kwaboniswa ukuba inokukhusela iseli somhlaza ekufeni, nangona emva kokuba iDNA yabo yonakaliswe yimitha okanye i-chemotherapy.
Ngoxa lo mgca wophando unomdla, unokudideka kwaye kunzima ukutolika. Izifundo kuyo nayiphi na yezi zifundo zifanele zibe namaqondo ahlukeneyo oxinzelelo, ngoko ke kunokwenzeka njani ukuba neqela "lokulawula", oko kukuthi, ungenakho uxinzelelo ukuthelekisa ezinye izifundo? Kunokwenzeka njani ukufumanisa ukuba iziphumo zamaselula ezibonwayo azibangelwa yimiba engozi yeso sifundo? Ngenxa yesi sizathu, ulwalamano olusondeleyo phakathi komphumo wokuxinzelela kunye nomhlaza alukwazi ukubonakaliswa.
Ngoku kutshanje, uphando olongezelelweyo luye lwaphakamisa ukuba uxinzelelo lunokuba lunobungozi ngokuchaphazela indlela yokubonisa imiba ebandakanyekayo kwintsebenziswano kunye nokusabalalisa (i-metastasis) yomhlaza.
Ukunyanzeliswa koxinzelelo lwezilwanyana
Ukwazi ukuba ngaphezu kokuchaphazela umgangatho wobomi, uxinzelelo lunokuba nempembelelo kwisiphumo sakho ngomhlaza, kubonakala ukuba ukulawula uxinzelelo kubaluleke kunabo bonke abantu abaphila nesifo.
Ukuba uhlala nomdlavuza, qalisa ngokukhangela ezi zinto zixhasayo.
Kanti kuhlale kulungile xa unokuthi ubulale iintaka ezimbini ngeeritye elinye. Kuye kwafunyaniswa iindlela ezininzi zengqondo / zomzimba ekuncedeni kuphela ukulawula uxinzelelo kwizigulane zomhlaza kodwa kunceda abo abanomdla ngezinye iindlela. Umzekelo, i- yoga yezigulane zomhlaza , ukucamngca izigulane zomhlaza , ukuxilisa izigulane zomhlaza , kunye ne- qigong yezigulane zomhlaza kunokunceda ukulawula uxinzelelo ngelixa kuncedisa nezinye iziphumo ezinomsindo ezibangelwa ukukhathala ukuya kubuhlungu obungapheliyo kwi-chemobrain.
Imithombo:
UHansen, F., noJaanwatzky. Ukuxinezeleka kwizigulane zomdlavuza wamaphaphu: impendulo yabantu kwisifo. Iforum yoLwazi lwabahlengikazi . 2008. 35 (2): 217-23.
Kanagasabai, R., Karthikeyan, K, Vedam, K. et al. I-DNA Imonakalo kunye nezimpendulo zengxowankulu yee-Cell Hsp27 Ikhusela i-Adenocarcinoma Iiseli ezivela kwi-UV-Indoped Apoptosis nge-Akt kunye neendlela ezi-21 ezixhomekeke zokusinda. Uphando lweCometer Cancer . 2010. 8: 1399-1412.
ULutgendorf, S., Sood, A., noMn. Antoni. Imiba yoMqhubi kunye nokuqhubela phambili komhlaza: iindlela zokungena kunye nokungenelela kwimiba. Umbhalo we-Clinical Oncology . 2010. 28 (26): 4094-9.
U-Moreno-Smith, uM., uLutgendorf, S., no-A. Sood. Impembelelo yoxinzelelo kumhlaza we-metastasis. I-Future oncology . 2010. 6 (12): 1863-81.
Nagaraja, A., Sadaoui, N., Dorniak, Pl, uLutgendorf, S., kunye no-A. Sood. SnapShot: Uxinzelelo kunye nezifo. Cell Metabolism . 2016. 23 (2): 388-388.e1.
Williams, J., Pang, D., Delgrado, B. et al. Umzekelo we-Gene-Environment Interaction ubonisa ukunyanzeliswa kweGland Genetic Extension and Increased Growor Growth emva kokuHlaliswa kweNtlalo. UPhando loPhando loPhando . 2009. Ingaba: 10.1158 / 1940-6207.CAPR-08-0238.