I-Lupus yimeko ehamba ngokuzenzekelayo engabangela i-pleurisy kodwa ibandakanyeke kwezinye iimeko ezithile zemiphunga. Ziziphi iimpawu, zifunyaniswa njani, kwaye zithini unyango lwe-pleurisy e-lupus? Ziziphi ezinye izifo zamaphaphu ezenzeka ngokuqhelekileyo phakathi kwabantu abane-lupus?
I-systemic lupus erythematosus (SLE), isifo esizimele, sisisifo seempawu.
Ihlasela umzimba omzimba kwaye inokuchaphazela yonke into ephuma kwilusu kunye namalungu angaphakathi.
I-Lupus yisona sifo esiqhelekileyo sesifo se-tissu ukuze sibe neempawu ze-pulmonary (lung). Uninzi lwabantu abaneepulus bahlakulela imimandla yamaphaphu, kwaye oku kubalulekile ekusalathweni kwesi sifo.
ULupus noPleurisy
I-Pleurisy (intlungu yesifuba se-pleuritic) yindlela eqhelekileyo yepulmonary (imiphunga) yokubonakalisa i-lupus. I-Pleurisy yi-diagnostic echazayo ebhekisela kwiintlungu ezitholakala ngexesha lokuphefumula (ngamanye amaxesha kuphela ngexesha lokuphefumula okanye ngexesha lokukhwehlela).
Ukuxhomekeka kwesi sibuhlungu kukuvuvukala kweembumba ezimbini ezibeka imiphunga ( i-pleura ). I-pleura ihlukaniswe ngumbutho omncinci obizwa ngokuba yintlambo yesigxina , equlethe iifatuni ezine zinezikhuni ezinezikhalazo . Ngokubambisana, i-pleura isebenza njengomkhumbi, ukunciphisa ukuxubana emiphakeni xa uphefumula nangaphandle.
I-lupus, autoantibodies (iintsholongwane ezijoliswe kwiisishu zakho) zijolise kwi-pleura, ukudala ukuvuvukala. Oku kuvutha kungakhokelela kwiintlungu ezenzekayo xa uphefumlela okanye uphume ngaphandle - nantoni na eyenza i-pleura ihambe. Ngamanye amaxesha ukuvuvukala kunobumnandi kwaye kuphazamisekile kwenzeka kuphela ngokuphefumula, ukukhwehlela, ukukrazula, okanye ukuphelelwa ngunyanzeliso.
Ngamanye amaxesha ukuvuvuka kunokuba nzima kakhulu, kubangela intlungu kunye nokuphefumula okuqhelekileyo.
Njengenye inkcenkcesho yale nkqubo, ukuvuvukala kunokubangela ukwakhiwa kwe-fluide phakathi kwe-pleura. Ukuphuphuma komsindo wempembelelo kungahlukahluka kwiimpawu ezingekho nanye (ukuba kunomlinganiselo omncinci we-fluid excessively) ukuphefumula kancinci nokuphefumula kunye nefuthe elikhulu lokuncengela elixinzelela imiphunga.
Masiqwalasele ngenyameko iimpawu, ukuxilongwa, kunye nonyango lwe-pleurisy, olulandelwe ukuhlaziywa okufutshane kwamanye amagciwane emiphunga anokudibana ne-lupus.
Iimpawu
Iimpawu ze-pleurisy ne-lupus zingaquka:
- Ubuhlungu ngokuphefumla, ukukhwehlela, okanye ukunyakaza kwesifuba (intlungu yesifuba se-pleuritic)
- Ubuhlungu ehlombe (ngenxa yokuvuvukala kwamathambo ehlombe elidlulayo
- Ukuphefumla okufutshane (xa kuqhutywe umonakalo ophilileyo, okanye ngenxa yokuphepha ukuphefumula okukhulu ngenxa yokungahambi kahle)
- Isantya sokuphefumula
- I-Cyanosis (iblueness yesikhumba kwi-oxygen deprivation). I-Cyanosis iyenzeka kuphela xa isixa esikhulu semithombo yamanzi egciniweyo iqokelela
Ukuxilongwa
Ukuxilongwa kwe-pleurisy ehlobene ne-lupus idla ngokusetyenziswa ngokudibeneyo kwimbali echanekileyo kunye neyomzimba, kunye neemvavanyo zesebhu kunye nezifundo zokucinga.
Imbali yeentlungu zesifuba se-lupus ne-pleuritic ingaba yiyo yonke into efunekayo ukuze ixilongwe xa izibonakaliso zincinci. I-pleura ihamba kakuhle, kodwa xa ichaphazeleka yi-pleuritis, iyaba yingozi, ixubusha kunye kwaye ivelise isandi, isandi. Esi sandi sivakala nge stethoscope, ngamanye amaxesha ngokubeka nje indlebe kwisifuba.
Ekubeni i-lupus idibene nezinye iimeko zemiphunga, ezinye iimvavanyo zenziwa rhoqo. Ezinye zazo zibandakanya:
- Umsebenzi wegazi - Iimvavanyo zegazi malunga ne-lupus (ukuba ezi zange zenziwe)
- Inani elipheleleyo legazi - I-CBC inokunceda ukulawula ezinye izizathu ze-pleurisy ezifana nezifo zentsholongwane okanye i-virus.
- I-x-ray yesifuba okanye i-CT scan.
- Ukuba i-pleusion effusion ikhona, i-thoracentesis idlalwa rhoqo. Kule nqubo, inaliti enhle ifakwa kwisifuba kwisikhala sokukhalaza ukukhupha umkhuhlane. Ukongezelela ekunciphiseni ubukhulu be-effusion effusion (ukuba ukuphefumla kufumaneka), lo mkhuhlane unokuhlaziywa kwibhule ukulawula ezinye izizathu ezinokubangela ukuchithwa.
Unyango
Akunakudla unyango oluthile lwe-pleurisy oluhambelana ne-pleurisy ngaphandle kokuba usulelo lwe-bacterial okanye utshosulelo lwentsholongwane lugxininisekile kunokuba lukhuphe ukukhupha. Ekubeni uhlobo lokuzimela kwe-lupus lujongene neempawu ezininzi zexesha, nokuba nayiphi na unyango olusetyenziswa ekuphatheni i-lupus, ngokubanzi, iya kubhekiswa kwi-pleurisy. I-Pleurisy ebangelwa i-lupus kufuneka iqhube ikhosi yayo ngexesha, kwaye intlungu inokulawulwa nezidakamizwa ezichasayo kuze kube yilapho isombulula.
Ezinye iindlela zokuthi i-Lupus iyakuthinta njani ii-Lungs zakho
Olunye uhlobo lwesimo somphunga luchaphazela kuma-50 ekhulwini labantu abane-lupus. Unokwenza oko ngokuchaphazela amaninzi ahlukeneyo kunye nezakhiwo zomphunga kuquka:
- Pleura (njengoko kuthethwa nge-pleurisy echazwe ngasentla)
- Izicubu zomzimba ngokwazo (izicubu ezinxibelelwano phakathi kwemiphunga)
- I-Alveoli ( iipoksi zomoya ezincinci kwimiphunga ejongene nokutshintshwa kwe-oxygen ne-carbon dioxide)
- I-Bronchi kunye ne- bronchioles (i-airways enkulu kunye encinci yemiphunga)
- Imithambo yegazi emiphakeni
- I-Diaphragm (njengokwehla kwe-lung syndrome exoxwa ngezantsi)
Izimo zonyango ezinxulumene nezilwanyana ezinxulumene neLupus
Ukongeza kwi-pleurisy, kukho ezinye izifo zamaphaphu ezenzeka ngokuqhelekileyo kubantu abane-lupus. Uninzi lwezi meko zinempawu zokukhwehlela, ukuphefumula okufutshane, kwaye ngezinye izihlandlo ukuphefumula ngegazi , ngoko ke kufuneka kuhlolisiswe ngokucophelela ukucacisa isizathu esicacileyo. Izimo zengxube (ngaphezu kwe pleuriy) ezidibene ne-lupus ziquka:
- I-Lupus i-pneumonitis (zombini isisigxina nesigxina) - I-Lupus pneumonitis ibhekisela ekuvukeleni kwamathanga emiphunga. Xa kunzima ukuba kubangele ukukhwehlela, ukuphefumula okufutshane kunye nentlungu ngokuphefumla? I-Steroids idla ngokusetyenziswa, kwaye iimeko eziphezulu zingafuneka.
- I-pulmonary hypertension - I- pulmonary hypertension yimeko apho uxinzelelo lwegazi ngaphakathi kwe-pulmonary art (umthambo ohamba ukusuka kwi-ventricle efanelekileyo yentliziyo emiphakeni) uphakanyisiwe, kwaye uvele kwi-10 ekhulwini yabantu abane-lupus.
- Ukunciphisa i-lung syndrome - Ukulimala nokuvuvukala kwesithsaba kungabangela imeko ebhekiselele ekunciphiseni i-lung syndrome. Le meko engaqhelekanga ibangela ukuphakama kwesithintelo, ukukhawulela indawo yamathambo emiphunga angasetyenziselwa ukutshintshiselwa kwegesi.
- Izifo zamaphaphu ezinjenge-pulmonary fibrosis - Izifo zengxowankulu zizifo ezithintekayo zemiphunga (ngokungafani neemeko ezifana ne-asthma kunye ne-emphysema eziphazamisayo izifo zemiphunga.) Ukuvuvukala okulandelwa ukutshatyalaliswa kwemiphunga kukuvimbela imiphunga ukuba ikhule ngokugcwele ngokuphefumula, ekunciphiseni umsebenzi wemiphunga.
- Ezinye izimo zemiphunga - Iimeko ezinjenge-pulmonary embolism, i-pneumothorax, ukuxhatshazwa kwexesha eliphindaphindiweyo, kunye ne-asthma zixhaphakile kakhulu kubantu abane-lupus Ukongeza kwesi simo, ingozi yomdlavuza wamaphaphu, ikakhulukazi i-squamous cell carcinoma yemiphunga, iphakamileyo kubantu abaye bafumanisa ukuba bane-lupus.
Okukwintsusa
Izifo ezigugu, njengoko ziphawulwe, ziqhelekileyo ne-lupus, ezichaphazela ngaphezu kwesigamu sabantu abane-lupus ngexesha elithile. Isimo esona siqhelekileyo yi-pleurisy, ukuvuvukala kweembrane ezibandakanya imiphunga ngenxa yenkqubo yokuvuvukala exhaphakileyo kwi-lupus. Nangona kungekho nonyango oluthile, kubalulekile ukuqinisekisa ukuba esinye sezifo zamaphaphu zifumaneka kubantu abane-lupus. Amanyathelo okunciphisa intlungu, njengamachiza, ukukhwehlela ukukhwehlela, nokuphepha ukuvuthwa okunzima okubangelwa ukuphefumla, kunokubanceda abantu bazive bekhululekile kude kube yilapho eso sifo siqhuba.
Imithombo:
Borrell, H., Narvaez, J., Alegre, J. et al. Ukunciphisa i-Lung Syndrome kwi-Systemic Lupus Erythematosus: Uluhlu lweeNqaku kunye nokuHlola kweeNcwadi. Amachiza (iBaltimore) . 2016. 95 (33): e4626.
Mittoo, S., kunye noCell. Ukubonakaliswa kwePulmonary ye-Systemic Lupus Erythematosis. Iimviwo kwiMpilo yeMpilo yokuHluma nokuHlola . 2014. 35 (2): 249-54.
Rosenberger, A., Sohns, M., Friedrichs, S. et al. I-Gene-Set Meta-Analysis ye-Lung Cancer ichonga indlela ehambelana ne-Systemic Lupus Erythematosus. PLoS One . 2017. 12 (3): e0173339.