I-Legless Leg Syndrome okanye i-Willis-Ekbom Izifo

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Ukunqongophala kweNsimbi

Nangona abantu abaninzi abaneemilenze zesifo esingenasiphako (RLS) abanakuze bakwazi ukufumanisa imbangela kwintlungu yabo, ngokuqhelekileyo kubangelwa kwezinye izizathu zesibini. Oku kubangela iindidi ezimbini zemo, i-RLS eyimfuneko (engaziwayo kwaye ihlala yintsapho) kunye ne-RLS yesibini. Kukho imeko ezininzi ezinokuzimela ngokuzimela kwiimpawu ze-RLS.

Isimo sokuqala esinokukhokelela kwimpawu ze-RLS yintsilelo yensimbi. Ubudlelwane phakathi kokunqongophala kwesinyithi kunye neempawu ze-RLS sele zifundwe ngokubanzi. Kwiinkalo ezininzi zophando, kufumaneka amanqanaba aphantsi entsimbi egazini kunye nomswakama omninzi wabantu abahluphekayo kwi-RLS. Amanqanaba entsimbi aphantsi, ezimbi ngakumbi iimpawu. I-IMRI ibonakalise ukuba umxholo wesinyithi kwindawo yengqondo ebizwa ngokuthi i-substantia nigra iyancipha kulabo abane-RLS xa kuthelekiswa nabantu abaqhelekileyo, abangabangela ukuba bangenayo ingxaki. Ukongezelela, uphando lwezilwanyana luye lwaqinisekisa lo tshintsho ngaphakathi kwengqondo.

Ngoko ke kunconywa ukuba unomgangatho wakho we-serum ferritin (umakishi wezitolo zentsimbi) ukhangele ukuba unempawu ze-RLS. Ukongezelela, ityala lokutshintshwa kwentsimbi ngomlomo ukuba amazinga aphantsi kufuneka ayenze. Kwabanye abantu abanamazinga avakalayo baphendula ngokufanelekileyo ukutshintshwa kwensimbi.

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Isigulo sokuphela kwesifo seengcinezelo

I-RLS iyinto eqhelekileyo phakathi kwabantu abanezifo zesifo sokuphela kwesigxina, ngokukodwa abo baxhomekeke kwi-dialysis. Iziganeko ziye zabikwa kwi-6 ukuya kwi-60 ekhulwini. Akucaci ukuba yintoni enokuba negalelo kwi-RLS kweli qela. Ukukhulelwa kwe-anemia, ukusilela kwesinyithi, okanye kunye namazinga e-hormone e-parathyroid angaba nenendima esekelwe kwizifundo ezahlukeneyo. Kwezinye iimeko, ukunyanga i-anemia ne-erythropoietin unyango okanye ukutshintshwa kwesebe kuye kwasebenza.

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Sikashukela

Kubantu abane-Type 2 okanye isifo sikashukela sabantu abadala, i-RLS ingahlakulela. Ukuba isifo sikashukela sishiywa singalawulwa, umonakalo weentliziyo ungabangela. Oku kucatshangelwa ukuba kwenzeka ngenxa yamanqanaba aphezulu e-glucose ngaphakathi kwegazi. Oku kungakhokelela kumonakalo wemida eminci yegazi enika iimbasa ezibizwa nge-vaso nervorum. Xa ezi zivalelwe, iimbilini ngokwazo ziyonakaliswa. Ngokuqhelekileyo oku kuholele ekutheni i-peripheral neuropathy, eneentlungu kunye nezikhonkwane-kunye-neenaliti ukuvakalelwa ezinyaweni. Oku kungaqhubela phambili imilenze kwaye kubandakanye nezandla. Edibaniswe nale nguqulelo yentshukumo, abanye abantu baya kuba neempawu zeRLS. Ngoko ke, kucatshangelwa ukuba isifo sikashukela sinokuba ngumngcipheko ozimeleyo wokuphuhlisa i-RLS. Kubantu abaye bafumana i-pancreas kunye nokuguquka kweengso, iimpawu zabo zeRLS ziphucule.

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Isifo sokugubhuka

Kukho ubungqina obunokukhula bokuthi i-sclerosis eninzi ibonakala ijongene nobungozi obuninzi be-RLS. Ezinye zezifundo ziphikisana, nangona kunjalo. Kwesinye sezifundo ezininzi ezazibandakanya izifundo eziyi-1,500, ukusabalalisa kweRLS kwakungama-19 ekhulwini kubantu abane-MS xa kuthelekiswa nepesenti ezi-4 kuphela zabantu abangenawo.

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Izifo zikaPasinson

Kucingelwa ukuba i-RLS kunye nesifo se-Parkinson sinokubangelwa yinkinga efanayo, oko kukuphazamiseka kwi-neurotransmitter dopamine. Oku akuqondwa ngokupheleleyo, nangona kunjalo. Kungakhathaliseki ukuba, i-RLS inokuthi ibekho kubantu abanesifo sika-Parkinson, ngokuxhaphaka ukususela kwi-0 ukuya kuma-20.8 ekhulwini, ukuhluka ngokusekelwe kwisifundo. Isifo sika-Parkinson sihlala siquka ukungazinzi (okubizwa ngokuba yi-akathisia) ehamba kunye ne-RLS, enokukwenza kube nzima ukuhlula phakathi kweziphazamiso. Xa zombini iimeko zikhona, i-RLS idlalwa emva kokuba isifo se-Parkinson sibonakala.

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Ukukhulelwa

Akuzona zonke iimeko ezingakhokelela kwi-RLS. Enyanisweni, ukukhulelwa kubonakala ngathi akunyanga nje kuphela iziganeko kodwa kunye neqondo leempawu ze-RLS. Kuhlolisiso lwabangama-626 abafazi abakhulelweyo, iipesenti ezili-10 kuphela ezineempawu ze-RLS ngaphambi kokukhulelwa kodwa oku kwanda ukuya kuma-27 ekhulwini ngexesha lokukhulelwa. Kwakubonakala kunzima kwi-trimester yesithathu. Iindaba ezilungileyo kukuba iimpawu ziphucuka ngokukhawuleza emva kokuziswa. Akucaci ukuba yintoni ebangela ukunyuka kwamaRLS ngexesha lokukhulelwa. Kungenzeka ngenxa yentsimbi okanye ukungabi nantwini okanye ngenxa yokutshintsha kwe-hormone ehambelana nokukhulelwa.

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Izifo zeRheumatic

Kukho imeko ezininzi ezinjenge-rheumatoid arthritis, i-Sjogren's syndrome, kunye ne-fibromyalgia enokubambisana nempawu ze-RLS. Olu budlelwane alucacanga. Kwesifundo esinye, iipesenti ezingama-25 zabantu abane-rheumatoid arthritis babenempawu ze-RLS xa kuthelekiswa ne-4 kuphela ekhulwini labo abane-osteoarthritis. Kwesinye isifundo, iigulana ezingama-42 kwezi-135 ezine-fibromyalgia zineRLS. Isizathu esona sizathu salolu dlelwane asiqondi kakuhle.

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Varicose Veins

Kwamanye amaxesha, ukuhamba kwegazi olubi kwimilenze kudibene neRLS. Ngokukodwa, iimvumba ezibuthakathaka eziphazamisayo kwaye zingakhathazeki ziye zatsholwa. Le mivumba ye-varicose ihlala ihlanganiswe kwaye iluhlaza okwesibhakabhaka kwaye ingaba ngumqondiso wokungenakwenzeka. Kuhlolisiso lwezigulane ezingama-1,397 ezineemvini ze-varicose, abantu abayi-312 bakhononda ngeempawu ze-RLS.

Ukwelashwa kwemivimbo ye-varicose kuboniswe ukuba kuphumelele ekunciphiseni ezinye iimpawu ze-RLS. I-Sclerotherapy yaholela ekuphuculweni kokuqala kuma-98 ekhulwini labantu, ngokukhululeka okugcinwe kwiminyaka emibini kwi-72 ekhulwini. Unyango lwamayeza, kuquka i-hyrdoxyethylrutoside, luye lwaboniswa ukuba lusebenza ngokuthobeka.

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Ezinye iimeko

Ngaphandle kweemeko ezichazwe ngasentla, zininzi nezinye iziphazamiso ezibonakala zihambelana neempawu ze-RLS. Ezi ziquka:

• Ukunyanya
• Hypothyroidism
• Igazi elonyukayo
• Isifo sentliziyo
• Iipheripheral neuropathies
• Ukungasebenzi kweVitamin
• I-cafeine eyininzi
• Ishukela eliphantsi kwegazi
• I-radiculopathy yeLumbosacral
• I stenosis
• Ukusetyenziswa kwe-mianserin (iyeza ezixinzelelekileyo)

Ukuba unemiqondiso yemilenze engenakuphumla, ngenhlanhla kukho imishanguzo enokusetyenziswa esonyango .

> Imithombo:

> Allen, RP et al. "Imilinganiselo ye-MRI ye-Brain Iron kwi-Patients Without Alessless Legs Syndrome." I- Neurology 2001; 56: 263.

> Connor, JR et al. Uvavanyo lwe-Neuropathological Examination Suggests Brain Brain Ukufunyanwa kwi-Restless Legs Syndrome. "I- Neurology 2003; 61: 304.

> Earley, CJ et al. "Ukungavumelekanga kwiinkcazo ze-CSF zikaFerritin kunye neTransferrin kwi-Restless Legs Syndrome." I- Neurology 2000; 54: 1698.

> Kavanagh, D et al. I-Syndrome ye-Legs ye-Restless i-patient "kwi-Dialysis." Ngaba iJ Kidney Dis 2004; 43: 763.

> Lee, JE et al. "Izinto ezibangela ukuphuhliswa kwemizimba engapheliyo yemilenze yezilonda ezigulane kunye nezifo ze-Parkinson." I- Mov Disord 2009; 24: 579.

> Manconi, M et al. "Imilenze yokungafihlayo imilenze nokukhulelwa." I- Neurology 2004; 63: 1065. I-American Academy yoLondolozo lweMpilo. Ulwahlulo lwaMazwe ngamazwe lweengxaki zokulala. 2005.

> Manconi, M et al. "Isifundo soLawulo lwe-Case-Control Multimenter kwi-Multiple Sclerosis: iSifundo se-REMS" Ukulala ngo- 2008; 31: 944.

> Merlino, G. et al. "Umbutho weSilly Legs Syndrome and Quality of Sleep in Type 2 Diabetes: Study Study Control." Ukulala ngo- 2007; 30: 866.

> Walters, A. "Iimpawu zeMilenze ezingapheliyo kunye neeNkqubela zePeriodic Sleeps." I- Continuum. Neurol 2007; 13 (3): 115-138.