I-Sweet's syndrome yimeko engaqhelekanga ebandakanya ukugqithwa okubuhlungu, ngokuqhelekileyo kunye nomkhuhlane. Ukukhawuleza kuqhuma kakhulu kwesikhumba seengalo, intamo, intloko kunye nesiqu. Isizathu se-Sweet's syndrome asiyazi ngokupheleleyo, kodwa kukho iimeko ezininzi ezaziwa ngazo ukuba zenzeke.
Kwabanye abantu, kubonakala kubangelwa ukusuleleka, okanye mhlawumbi inxulumene nesifo sesibindi sokukhulelwa kunye nokukhulelwa; kwabanye, inokudityaniswa nomhlaza, ngokuqhelekileyo i-leukemia yesifo esingaqhelekanga; kanti abanye banesimo esibangelwa yiziyobisi se-Sweet's syndrome.
I-Sweet's syndrome isenokuthi ihambe yodwa, kodwa iqhutshelwa ngokuphathwa ngamapilisi e-corticosteroid, njenge-prednisone. I-Sweet's syndrome yaziwa ngokuba yi-acute febrile neutrophilic dermatosis okanye isifo se-Gomm-Button.
Iimpawu
I-Sweet's syndrome ibhalwe yimpawu ezilandelayo:
- Fever
- Ubomvu obomvu kwizandla, entanyeni, entloko okanye kwisiqu esikhula ngokukhawuleza, sisasazeka kwiinqela ezibuhlungu ukuya kwi-inch okanye ngoko ububanzi
- I-Rash ingabonakala ngokukhawuleza emva komkhuhlane okanye ukusuleleka kwintsholongwane yokuphefumula .
Iintlobo ze-Sweet's Syndrome
Le meko iboniswe ngeentlobo ezahlukeneyo ezintathu:
Zasendulo
- Ngokuqhelekileyo kubasetyhini abaneminyaka engama-30 ukuya kuma-50 ubudala
- Ngokuqhelekileyo ilandelwa yintsholongwane ephezulu yokuphefumula
- Unokuthi unxulumane nesifo sesibindi sokukhukhumeza nokukhulelwa
- Phantse i-1/3 yezigulane zinokuphindaphinda kwe-Sweet's syndrome
Malignancy-Associated
- Mhlawumbi ube ngowomntu owaziwa ukuba nomhlaza
- Mhlawumbi makube kumntu onomdlavuza wegazi okanye i-tumor eqinile ngaphambili engafumanwanga
- Ininzi ixhomekeke kwi -leukemia enesifo esibi , kodwa ezinye i-Cancer, ezinjengombele okanye ikholoni
Ukusetyenziswa kweziyobisi
- Okuqhelekileyo kubakho kwizigulane eziye zanyangwa nge-granulocyte-colony evuselela into eyenzelwe ukukhulisa iiseli zegazi ezimhlophe
- Nangona kunjalo, amanye amayeza anokunxulumaniswa; iziyobisi ezinxulumene ne-Sweet's syndrome zibandakanya i-azathioprin, i-antibiotics ethile kunye nezinye izidakamizwa ezichasayo
Ukubandakanya Ngaphandle kwesikhumba
Ngenxa yokungabikho kwe-Sweet's syndrome, idatha echanekileyo, kunye nemimandla engaphantsi kwemiqathango, kungekhona zonke iziphumo ezixhomekeke kule ngxaki zivela kwi-syndrome ngokwayo.
Oko kwathiwa, I-Sweet's syndrome kucingelwa ukuba iquka ezinye iisculi kunye nezitho, ngaphezu kwesikhumba. Ukubandakanywa kwamathambo namalungu kuye kwabhalwa, njengokuba kuthathwa inxaxheba kwinkqubo yesistim ephakathi-"i-neuro-Sweet disease" ichazwe. Amehlo, indlebe, nomlomo nazo ziyachaphazeleka. Iibhokhwe ezibomvu zincinci ziyakwandisa ukusuka kwindlebe yangaphandle, kwi-canal kunye ne-eardrum. Amehlo angabandakanyeka, ngokuvuvukala, ubomvu, nokuvuvukala. Izilonda ngolwimi, ngaphakathi kwezihlathi kunye neentlobo ezinokuthi ziphuhlise. Ukuvuvukala kunye / okanye ukwandiswa kwezitho zangaphakathi zesisu nesifuba kuye kwabikwa.
Izinto zobungozi
I-Sweet's syndrome ayinqabile kakhulu, ngoko ke ingozi yazo ingabonakali kakuhle njengoko ikhona ezinye izifo. Ngokuqhelekileyo, abasetyhini banakho ukufumana i-Sweet's syndrome kunamadoda, kwaye, nangona abantu abadala kunye nabantwana banokuvelisa i-Sweet's syndrome, abantu abaphakathi kweminyaka engama-30 no-60 bangamaqela angamaqela athathaka.
Ukongezelela, iimeko ezichazwe kwiintlobo ezichazwe ngasentla zinokuthi zithathwe njengengxaki yomngcipheko, ngoko-ke i-Sweet's syndrome ngezinye izihlandlo ihambelana nomhlaza, inokuthi idibanise novelwano kwizilwanyana ezithile, inokulandela ukusuleleka kwintsholongwane yokuphefumula zifana neempawu ngaphambi kokuba kuvele ukugqithisa) kwaye kunokunxulumana nesifo sesibindi sokuvuvukala, esiquka isifo sikaCrohn kunye nesifo sokulonda.
Abanye abafazi baye bahlakulela i-Sweet's syndrome ngexesha lokukhulelwa.
Ukuxilongwa
I-Sweet's syndrome inokukrokra okanye iyaqatshelwa ngokuhlolisisa ukukhawuleza, nangona kunjalo, kukho iimvavanyo ezahlukahlukeneyo kubalulekile ukuba kwenziwe ukuxilongwa kunye / okanye ukulawula ezinye izizathu.
Isampuli yegazi lakho inokuthunyelwa kwibhubhoratri ukuba ikhangele inani elingaqhelekanga lamaseli ezimhlophe kunye nokuba khona kweengxaki zegazi.
I-skin biopsy, okanye ukususwa kwecandelo elincinci lekhupha elichaphazelekayo ukuhlolwa phantsi kwe-microscope, inokwenziwa. I-Sweet's syndrome ineziganeko ezingaqhelekanga: iiseli ezivuthayo, izityalo zegazi ezimhlophe eziqhelekileyo ze-neutrophil, zingena ngaphakathi kwaye zihlala kwindawo engaphezulu kwendawo ephilayo yesikhumba.
Ingqalelo, ii-agent ezithathelwanayo zingavelisa iziphumo ezifanayo kwesikhumba, ngoko kuye kwacetyiswa ukuba kungengqiqo ukufumana isampuli evivinywa kwiibhaktheriya, i-fungi, kunye neentsholongwane.
Iziphumo zebhoratri ezihambelana nezigulane ezineSondy syndrome ziphakanyisiwe iiseli zegazi ezimhlophe kunye neutrophils egazini kunye ne-erethrocytes sedimentation rate, okanye i-ESR. Oko kwathiwa, inani eliphezulu legazi lamhlophe alisoloko libonwa kuzo zonke izigulane ezine-biopsy-confirm confirmed syndrome.
Unyango
I-Sweet's syndrome isenokuhamba yodwa, ngaphandle kwonyango, nangona unyango lusebenza kwaye lusebenza ngokukhawuleza. Ukungathandabuzeki, ukukhawuleza kunokuhlala kwiiveki ukuya kwiinyanga. Amachiza aqhelekileyo asetyenziswa kwi-Sweet's syndrome yi- corticosteroids . I-corticosteroids yomlomo, njenge- prednisone , isenokusetyenziswa, ingakumbi ukuba unemihlaba embalwa yesikhumba echaphazelekayo. Ezi zonyango ziyi-systemic, oku kuthetha ukuba ziyahamba kuwo wonke umzimba kwaye kungekhona nje isikhumba.
Ezinye iintlobo ze-steroids ezifana nama-creams okanye ama-ointments ngamanye amaxesha zisetyenziselwa iincinci ezincinci. Xa umntu onentsholongwane kaTweet akayinyamezeli inkqubo ye-corticosteroids okanye eneempembelelo nge-corticosteroids yexesha elide, kukho ezinye iyeza ezinokusetyenziswa, ezifana ne-dapsone, iodidi i-potassium, okanye i-colchicine.
Izigulane nge-Sweet's syndrome zingaba neengxaki ngenxa yokubandakanyeka kwesikhumba, iimeko ze-Sweet's syndrome-ezihambelana nezifo, okanye zombini. Ulwaphulo lwe-antimicrobial lungasetyenziselwa ukuba izilonda zesikhumba ezivela kwi-rash zisengozini yokutshatyalaliswa okwesibini.
Ukuqwalaselwa kwanoma yiyiphi imeko enxulumene ne-Sweet's syndrome inokuba yinto ebalulekileyo yonyango lwe-Sweet's syndrome, ngokwalo. Ngokomzekelo, iimpawu ezinxulumene nesifo ngezinye izihlandlo zixhomekeke kunyango okanye kunyango lwesifo esichengileyo.
ILizwi
Amachiza afana ne-corticosteroids anokubonelela ngokukhululeka kwi-syndrome, kodwa ingqalelo kwiimeko ezinxulumene nazo zingabalulekile. Ukuba unesifo esibangeliswa yiziyobisi se-Sweet's syndrome, emva kokuba isicatshulwa sogqirha sinqunywe, isifo ngokuqhelekileyo, kodwa asihlali ngaso sonke isikhathi, siphucula kwaye sizithumela ngokukhawuleza.
Ngokucacileyo, akubona wonke umntu onesifo se-Sweet's has cancer; kwaye, kwisifundo kunye nabantu abangama-448 abane-Sweet's syndrome, iipesenti ezingama-21 kuphela (okanye i-96 yabantu abangu-448) zifunyenwe ukuba zinobungozi obuthakathaka okanye isisu esinamandla. Ingqalelo, nangona kunjalo, ukuba i-Sweet's syndrome ngamanye amaxesha kunokukhokelela ekufumaneni umdlavuza ongaziwa-kwaye kwakhona ukuba ukuphindaphinda kwesifo se-Sweet's syndrome esichaphazelekayo kunokubonisa ukuphindaphinda komhlaza.
> Imithombo:
> Cohen PR. I-Sweet's syndrome - uhlolo olubanzi lwe-febrile neutrophilic dermatosis. I-Orphanet J Rare Dis. 2007; 2: 34. i-doi: 10.1186 / 1750-1172-2-34.
> Hussein K, Nanda A, Al-Sabah H, Alsaleh QA. I-Sweet's syndrome (i-acute febrile neutrophilic dermatosis) ehambelana ne-adenocarcinoma yeprotate kunye ne-transitional cell carcinoma ye-urinary bladder. J Eur Acad Dermatol Venereol. 2005: 19: 597-599.
> I-RD. I-acute febrile neutrophilic dermatosis. Br J Dermatol. 1964; 76: 349-356. i-doi: 10.1111 / j.1365-2133.1964.tb14541.x.