Ukungafani phakathi kweeNicin Supplements
I-Niacin iye yongezwa ngokunyanisekileyo kulabo bazama ukugcina amanqanaba abo e-lipid kwindawo efanelekileyo. Izifundo zibonise ukuba i-niacin inokunciphisa i- cholesterol ye- LDL kunye ne- triglycerides kwaye inokuphakamisa i- cholesterol ye- HDL . Ngenxa yokukwazi ukuchaphazela zonke iinkalo zeprofayili yakho yepilid, kungase kube nzima ukuba uye kwi-pharmacy yakho yangasese okanye kwisitolo sokutya sezempilo ukuze ufumane ibhotile.
Nangona kunjalo, xa ufika kwicandelo le-niacin le-supplementary aisle, unokuhlangabezana neentlobo ezininzi ze-niacin supplements. Ngaphambi kokuba ufikelele kwibhotile ye-niacin, funda indlela yokwahlula phakathi kweentlobo ezahlukeneyo ze-niacin onokuzifumana kwi-shelf.
Xoxa noMboneleli wakho wezeMpilo kuqala
Ngaphambi kokuba uthenge kwaye uqale ukuthatha isongezelelo se-niacin-okanye nayiphi na inkxaso-kufuneka uthethe nomboneleli wakho wezempilo. Nangona i-niacin ibonakala iphucula iphrofayili yakho ye-lipid, uhlolo lwe-2017 uCchrane lwezifundo ze-niacin lufumene ukuba inzuzo yonyango lwe-niacin ukukhusela isifo senhliziyo okanye ukunciphisa ukufa kwakungenakwenzeka, ngokuthe ngqinela ubungqina obuphezulu.
Isifundo esisodwa esikhulu (ukufundwa kwe-AIM-HIGH) sibonise ukuba ukuthatha i-niacin eyongezelelweyo yokukhululwa kunye nesimo somzimba akuthinteli izifo zentliziyo. Ukongezelela, abantu abathile bathatha i-niacin kule sifundo babekho iziganeko eziphezulu zokufumana isifo se - ischemic .
Nangona uninzi lwe-niacin luthengiswa nge-counter-counter-, le nto ayithethi ukuba ayinakuchaphazela impilo yakho. Ngokomzekelo, i-niacin inokusebenzisana namanye amayeza owathathayo. Ukongezelela, i-niacin inokubangela iziphumo ezisecaleni okanye ukugqithisa imeko ezithile zonyango.
Izikhokelo zamanje azicebisi ukusetyenziswa kwe-niacin ekuphatheni amazinga e-cholesterol.
Ukuba umboneleli wakho wezempilo uthi kulungile ukuba ungeze i-niacin kwi-regimen yakho yokunciphisa i-cholesterol, kufuneka uxelele ukuba uthatha i-niacin, kunye nayo nayiphi na enye i-supplementary and medications oyithathayo, kubo bonke ababonelela ngezempilo. Oku kuya kubanceda ukuba bahlolisise nayiphi na intsebenziswano yeziyobisi okanye iimeko zonyango ezingaphuhlisa.
Azikho zonke iiNicin Supplements ezenziwe zilingana
Kukho iintlobo ezintathu eziphambili ze-niacin ezifumaneka ngaphaya kwe-counter njengesixhasayo:
- Nicotinic acid
- Nicotinamide
- I-inositol hexanicotinate (i -niacin engenamanzi )
Uninzi lweziphumo ezivavanya umphumo we-niacin ekunciphiseni amazinga e-lipid ziye zabandakanya ukusebenzisa i-nicotinic acid. Nangona i-nicotinamide kunye ne-inositol i-hexanicotinate yintlobo eyaziwayo ye-niacin ngenxa yokungabikho kokuhlanjululwa okunxulumene ne-nicotinic acid, kukho ubungqina obuncinane bokuthi le ndlela ye-niacin inokunciphisa amanqanaba e-lipid. Nangona ezininzi iibhotile zingabhalwa njenge-niacin, kufuneka uqwalasele ilebula yebhotile ukuqinisekisa ukuba uluphi uhlobo lwe-niacin.
Iintlobo ezahlukeneyo zeNicotinic Acid
I-Nicotinic acid, ebonise kwiziphumo ukuba nefuthe elihle kwiprofayili yakho yepilid, iyafumaneka kwiindidi ezahlukeneyo :
- Ukukhululwa ngokukhawuleza (IR) nicotinic asidi yindlela ye-nicotinic acid echithwa kwigazi ngexesha elinye. Nangona ufumana le dose ye-nicotinic acid ngexesha elifanayo, oku kunokukwenza ukuba ube nemiphumo emibi, njengento yokutshiza kunye nokunyanzelisa.
- Ukukhululwa okukhuselekileyo (SR) i-nicotinic acid ikhutshwe ngokuthe ngcembe kwinqanaba legazi kwaye inokunciphisa ezinye iziphumo ezingathandekiyo ezichaphazelekayo kunye ne-nicotinic therapy.
- Ukukhululwa okwandisiweyo (ER) i-nicotinic acid ikhutshwe kwixesha elincinci lexesha kodwa lifumaneka kuphela ngumyalelo odokotela.
Amandla e-Niacin Supplementary Vary
Ukuqulunqwa kwama-niacin angaphaya kwamanqanaba angatshintsha ngamandla kwaye ingaba nezinye iivithamini, amaminerali kunye nemifuno. Kubaluleke kakhulu ukuba ukhangela iilebula yomenzi kwibhotile ngokuphathelele izikhokelo malunga nendlela yokuthatha imveliso kunye nezinye izithako ekuncediseni ukuze uphephe imiphumo emibi-kwaye mhlawumbi ungakusindisa imali.
Umboneleli wakho wezempilo unokukunceda ukuba ubone ukuba yeyiphi i dose ukuthatha kunye nezindlela zokuthintela iziphumo zecala xa uqala unyango lwe-niacin.
> Imithombo:
> Abaphenyi be-AIM-HIGH, uBoden WE, Probstfield JL, Anderson T, Chaitman BR, Desvignes-Nickens P, Koprowicz K, McBride R, Teo K, Weintraub W. Niacin kwizigulane ezine-HDL ze-Cholesterol ezisezantsi. I-New England Journal of Medicine . 2011; 365 (24): 2255-2267. i-doi: 10.1056 / nejmoa1107579.
> Mackay D, Hathcock J, Guarneri E. Niacin: iintlobo zeekhemikhali, ukungabikho kwemvelo kunye nemiphumo yempilo. Uhlolo lweZondlo . 2012; 70 (6): 357-366. i-doi: 10.1111 / j.1753-4887.2012.00479.x.
> Ukulawula i-Cholesterol yegazi kwiBantu abadala: UkuBuyelwa koBungqina boBungqina obuvela kwiPhaneli leConstant Expert, ngo-2013. I-Heart Heart, iLung ne-Blood Institute.
> Schandelmaier S, uBriel M, Saccilotto R, et al. I-Niacin yokukhusela okuphambili kunye nesekondari yeemeko zenhliziyo. I-Cochrane Database yeeNkqubo eziPhezulu . 2017. Ithenda: 10.1002 / 14651858.cd009744.pub2.