Indlela uKreutzfeldt-Jakob Izifo ezihluke ngayo kwi-Alzheimer's

Ezi Zihlandlo Ngamanye amaxesha zikhohliswa ngokuba zibizwa ngokuba yi "Mad Cow Disease"

Yintoni iCreutzfeldt-Jakob Disease (CJD)?

UCreutzfeldt-Jakob (obizwa ngokuba yi-CROYZ-wayevakalelwa yi-YAH-cob) isifo esiyintlekele engqondweni esingaqhelekanga esichaphazela ngomntu omnye kwisigidi. Ngenye yeentlobo zezifo ze-prion.

I-CJD inokuthi iphinde ihanjiswe njenge-spongiform encephalopathy, vCJD, kunye no-Jacob-Creutzfeldt.

Ukukhula

I-United States inee-200 ukuya kuma-300 matyala ngonyaka.

Umyinge weminyaka yobudala uneminyaka engama-60 ubudala.

Iimpawu zeCJD

Izimpawu zakudala kakhulu ziquka ukunqumla ukungaxineki-, ukuguquka kwemizwelo kunye nokungabikho komdla kubantu okanye kwiimeko. Ngokukhawuleza, ezinye iimpawu ziphuhliswa, kubandakanywa iingxaki zememori , ukuguquka kwendlela yokuziphatha, ukulungelelanisa ukulungelelanisa, ukuhamba okungahambiyo kunye nokuphazamiseka kombono.

Njengoko eso sifo siyaqhubeka siphuthuka, abantu abaneCJD banokufumana i- hallucinations , ingqondo yengqondo, ukungonakaliswa kokulungelelaniswa, ukunyakaza okungenakuzibandakanya, iingalo ezibuthakathaka kakhulu nemilenze, ukukwazi ukugwinya nokuthetha, kunye nokuphazamiseka kwengqondo. Ekugqibeleni, umntu unokungena kwi-coma.

Izigaba zeCJD

• Ngokukhawuleza
  I-CJD ye-Sporadic yenza malunga nama-85% kuwo onke amacala esi sifo. I-sporadic ithetha ukuba akukho nto ecacileyo.

• Hereditary
  Ngokutsho kweNational Institute of Neurological Disorders and Stroke, iimeko ezizuzwe njengefa ziba malunga nama-5% ukuya kwi-10% ekhulwini. Iprothini yeprothini yegciwane ayiqhelekanga kubantu abaneentlobo zeCJD. Kwizigulane ezinamafomu omzimba, utshintsho luye lwafunyanwa kwi-prion protein yegene eyenza iiprotheyini ezingabonakaliyo. Aba bantu baninzi babonisa imbali yentsapho yesifo se-prion.

• Ifunyenwe
  Kukho iintlobo ezintathu zeCJD ezifunyenweyo. Ezi ziquka:

1. Iatrogenic
   Oku kubhekisela kwi-CJD enikwe isivumelwano ngeenkqubo zonyango, ezifana nezixhobo ezingaqinisekanga okanye ukufakelwa kwezicubu.
2. Kuru
   I-CJD inokufunyanwa ngokusebenzisa i-cannibalism, ebizwa ngokuba ngu-Kuru. Le nto ibuyele kuma-1950, xa abantu besizwe sangaphambili ePapua, iNew Guinea-gama bahlakulela amacala amaninzi e-CJD kuba umngcwabo wabo wawuquka abafazi kunye nabantwana abadla ubuchopho bomfi. Njengoko lo mkhuba usuphelile, iimeko zeCJD zinciphile, kodwa le nto ithathe iminyaka emininzi kuba ixesha lokutshatyalaliswa kwe-CJD libonakala lide lineminyaka engama-40.

1. Uhlobo
   I-CJD eyahlukileyo icingelwa ukuba ibangelwa kukutya inyama enokusuleleka kwaye ingenzeka kubantu abancinci, abaneminyaka engama-avareji yokuqala eyenzekayo ngo-28. Oku kudla ngokuthethiwa ngokungafanelekanga ngokuthi isifo seenkomo esibi okanye isifo se-spongiform encephalopathy. Isifo seenkomo seMad senziwa kuphela kwiinkomo; xa idluliselwa kubantu, ibizwa ngokuba yiCJD ehlukile. Olu hlobo lwe-CJD alufanekanga; Amatyala amathathu kuphela aqoshiwe eUnited States, kunye nababini kulabantu ababekade bephuma kweli lizwe.

Ukuchonga i-CJD

Njengeminye imiba yeengxaki zegazi, akukho vavanyo olulula ukuxilonga i-CJD. Injongo yokuqala yogqirha kukulawula ezinye iimeko ezinokubangela ukuphazamiseka kwengqondo, ingakumbi kuba ezinye izimbangela ze-dementia ziguqulwa, ezifana nokunyanzeliswa kwengcinezelo ye-hydrocephalus kunye ne- vitamin B12 .

Iimvavanyo ezinjenge- tapin tap , i- EEG , i- CT kunye ne-MRI ingasetyenziselwa ukucacisa ubunzima beCJD.

Ukuqinisekisa ukuxilongwa, oogqirha banokwenza i-biopsy ngokususa inxalenye encinci yengqondo ukuvavanya. Enye indlela yokwenza i-autopsy emva kokufa. Nge-biopsy kunye ne-autopsy, kukho ingozi yokuba ugqirha aphethwe yi-CJD xa ephethe izicubu zeengqondo. Kwi-CJD eyahlukileyo, kukho iimeko eziqinisekisiweyo emva kokususwa nokuvavanywa kweetoni zomntu.

Ngoko ke kubaluleke kakhulu ukuba amanyathelo okulondoloza amanyathelo athathwe ngexesha leenkqubo.

I-CJD ihluke njani kune-Alzheimer's?

Ukunyuka kwe-CJD kukukhawuleza kunokuba ku- Alzheimer's disease . Abantu abane-CJD bahlala befa kwiiveki ezimbalwa ukuya kunyaka owodwa. Kwi-Alzheimer, kukho ukuhla kwehla ngokukhawuleza kwixesha leminyaka emininzi.

Unyango lweCJD

Okwangoku, akukho unyango lwe-CJD, nangona ezinye zeempawu ziyakunqulwa yimithi. Injongo kukubonelela nokukhupha. Uphando luqhubekile luqhutyelwa ekuchongeni izizathu kunye nemichiza ekhoyo yokuphatha i-CJD.

_Imithombo:

_{ADAM Creutzfeldt-Jakob Disease.Yenzeke ngoFebruwari 10, 2012. http://adam.about.net/encyclopedia/infectiousdiseases/Creutzfeldt-Jakob-disease.htm}

_{I-Alzheimer's Association. I-Creutzfeldt-Jakob Izifo. Kufumaneka ngoFebruwari 10, 2012. http://www.alz.org/alzheimers_disease_creutzfeldt_Jakob_disease.asp}

_{I-Creutzfeldt-Jakob Disease Foundation, Inc. I-CJD Fact Sheet. Kufumaneke ngoFebruwari 10, 2012. http://www.cjdfoundation.org/fact.html}

_{I-Creutzfeldt-Jakob Disease Foundation, Inc. I-Creutzfeldt-Jakob Izifo kunye nezinye izifo ze-Prion. Kufumaneka ngoFebruwari 10, 2012. http://www.cjdfoundation.org/pamphlets.html}

_{Umbutho WezeMpilo Wehlabathi. Isifo seCreutzfeldt-Jakob. Kufumaneka ngoFebruwari 10, 2012. http://www.who.int/topics/creutzfeldtjakob_syndrome/en/}