Ngaba i-Epi-Pen okanye i-Auvi-Q ifowuni ikhetha?
I-Anaphylaxis yindlela ebangela ukuguqulwa kwamagciwane okubangelwa ukukhululwa kwe- histamine kunye nabanye abalamli bezilwanyana ngenxa ye-cross-linking of antibodies anti-physically in cells cell and basophils .
Uninzi lweempawu ezihlukeneyo ziye zaxelwa ukuba zenze i-anaphylaxis, kuquka ukutya , inambuzane yesifo , i- latex , kunye neyeza . Izimpawu ze-anaphylaxis ziquka i- urticaria / angioedem , iimpawu zesifuba, isisu esisisigxina, ukutshatyalaliswa kwanokufa.
Ukhetho olukhethiweyo lwe-anaphylaxis yi-epinephrin, enikwa njengengxube ye-intramuscular. U-Epinephrine yodwa unyango lwe-anaphylaxis oluye lwaboniswa ukunciphisa ithuba lokufa, ngokukodwa xa lilawulwa ngokukhawuleza.
Kubantu abasemngciphekweni we-anaphylaxis ukusuka kwintlungu ekhuselekileyo, i-epinephrin kufuneka ifumaneka ngokukhawuleza ukuze ilawule ukuphazamiseka okukhulu. I-epinephrine auto-injection ziye zafunyanwa iminyaka emininzi, kunye nefomu ethandwa kakhulu yi- Epi-Pen . I-Epi-Pen yinto efakwe njengefenethi yokubhala, kunye nenqwelo yokukhusela kwiphepha elinye kunye nenaliti ephethe intwasa komnye. Ukuze usebenze i-Epi-Pen, kufuneka ukhutshwe ikhutshulwa yokhuseleko kunye nokuphela kunye nenaliti elayishiwe entwasahlobo. Ngelishwa, kuyaqhelekileyo ukuba abantu bazame ukusebenzisa i-Epi-Pen ukuyibuyisela emuva, kubangele ijojo engenalutho kwisigodlo - esisibini sibuhlungu kwaye asivumeli ukutyunjwa okufanelekileyo kwe- epinephrin emzimbeni ukuze kulandelwe iimpawu anaphylaxis.
Ngoku kutshanje, uhlobo olutsha lwe-epinephrine auto-injection lwaphuhliswa, olubizwa nge- Auvi-Q . I-Auvi-Q ifaka indlela yokukhusela isitifiketi ekupheleni kweedaliti yesistim kwaye isebenzisa isimiso se-prompt voice esinikeza imiyalelo yesinyathelo ngeyinyathelo malunga nendlela yokusebenzisa ifowuni ukwenzela ukukhusela izitenki zeenaliti zengozi.
Ngokungafani ne-Epi-Pen, i-Auvi-Q yinkqutyana encinci yeekhonsathi, malunga nobukhulu bekhadi lesikweletu.
Uphando olutshanje lufuna ukufumanisa ukuba yiyiphi idivayisi, i-Epi-Pen okanye i-Auvi-Q, ikhethwa ngabantu abafuna ukuphatha i-epinephrine auto-injection ukuze kunyango lwe-anaphylaxis. Abantu abangaba ngu-700 beemveli ezahlukileyo kunye nemvelaphi eyahlukileyo bathathe inxaxheba kwisifundo, eshicilelwe ngo-2013. Abathathi-nxaxheba banikwe imeko apho babenza ukuba bafumana i-anaphylaxis efuna ukusetyenziswa kwe-auto-injector epinephrine . Baye banikwe inguqu yoqeqesho nganye kwisixhobo ngasinye (esingenalo inaliti okanye i-epinephrine yangempela) kwaye yacela ukuba ibone indlela yokusebenzisa ifowuni. Emva kokuba imeko iphelile, abathathi-nxaxheba babuzwa malunga nokukhetha kwabo kwesinye isixhobo ngokunye.
Okumangalisa kukuba, i-Auvi-Q yayikhethwayo, malunga ne-4 ukuya kwe-1, phezu kwe-Epi-Pen malunga nayo yonke imilinganiselo yokuthelekiswa. Ezi zikhethwayo ziquka indlela yokufundisa, ukukhethwa kweyiphi idivaysi ukuba ithwale, kunye nobukhulu kunye nesimo seso sixhobo. Abathathi-nxaxheba bafumana i-Auvi-Q elula kakhulu ukuyisebenzisa, kulula ukuyithwala, kulula ukuyilandela imiyalelo, kwaye ikhethwa ngokubanzi xa kuthelekiswa ne-Epi-Pen.
Okubaluleke kakhulu, abathathi-nxaxheba babehlala bekwazi ukusebenzisa i-Auvi-Q ngokufanelekileyo (81%) xa kuthelekiswa ne-Epi-Pen (61%).
Njengomntu ongu-allerergist , ndifumana iziphumo zolu pho nonokholo. Okokuqala, inkampani eyenza idivayisi ye-Auvi-Q ikhokhele ukufundisisa - oku kuphelisa ukungavumelekanga isifundo kwimbono yam. Oku akugcini nje ukwenza ukuba abalobi be-study bahlasele i-Auvi-Q, kunokukwenza ukuba abathathi-nxaxheba bahlasele i-Auvi-Q ngokunjalo (kuba abathathi-nxaxheba bahlala behlawulwa ngenxa yeengcamango zabo, kwaye mhlawumbi bayazi ukuba bahlawulwa umenzi wesitsha esitsha). Emva koko, ndihlolisise izixhobo zombini kwaye ndicinga ukuba i-Epi-Pen iya kuba yinto ekhethekileyo kwi-Auvi-Q esekelwe kumava am nje njengomntu ongenayo i-anaphylaxis.
Ekugqibeleni, naliphi na ukufundisisa okunjengale nto kubonisa ukubahluko omkhulu phakathi kwamaqela amabini, ndicinga ukuba isifundo sincinane.
Ngoko ke, ngelixa kukho ixesha apho ndiza ku-Auvi-Q, ndikhetha ukunika i-Epi-Pen izigulane zam ezisemngciphekweni we-anaphylaxis. Ingqalelo, andihlawulwa yinkampani eyenziwa ngabafaki okanye isistim.
Umthombo:
UCamargo CA, iGuana A, Wang Wang, uSimons FER. I-Auvi-Q Versus Epi-Pen: Iinqununu zabantu abadala, Abanakekeli nabantwana. J Allergy Clinil Immunol: Kwenzeni. 2013: 1: 266-72.