Enye yeethemba ezinzulu zokwelapha i-stem cell re-upeneral isingeniso sokwandisa izitho eziphilileyo ukususela ekuqaleni. Ngasekupheleni konyaka we-2014, i- MedPage Today ibike ukuba abaphandi baseNew York City babelungelelanisa amangqamuzana e-embryonic stem kwiiseli ze-thyroid, kwaye bahlola amathuba okudala i-thyroid gland njengegulane kwiigulane eziye zavuthwa.
Uphando lwabhengezwa kwintlanganiso yama-American yeTyroid ye-2014.
Ngokwe-R. Michael Tuttle, MD of Memorial Sloan I-Cantering Center kwiNew York City, umongameli we-ATA program yesayensi: "Kuya kuba mnandi ukukwazi ukubuyela kwi-thyroid evamile." Njengengxenye yolu cwaningo, uTerry Davies, MD kunye nabalingane bakhe eSibhedlele saseNtaba saseSinayi eNew York City baphanda ngeendlela ezintsha zokunciphisa amangqamuzana e-embryonic stem kwiiseli ze-thyroid.
Nangona i-thyroid ye-tissue-transplant ingaphumelela ekugqibeleni, asikho kwindawo apho izigulane zisesigxina se-stem esakhiwe yi-cell. Kodwa oogqirha benza ukunyuswa kwezokwelapha namhlanje, ukunyanga ezinye izigulane ze-thyroid kunye ne-endocrine zineentlobo ezahlukeneyo zeselithi: i-cell stem cells, ii-autologous mesenchymal cells. Lezi zisele ze-stem zivela kwisigulane se-adipose (i-fatty) yesigulane, kwaye ayithwali nanye imiba yokuziphatha kunye neengxabano ezithintela amangqamuzana e-embryonic stem cells.
Ukusebenzisa iteknoloji ephawulwa yi-Cell Surgical Network, inani lamagqirha lenza izicelo zophando ze-adult stem cell evuselela unyango kwiinkqubo ezichazwa ngokuthi "uvavanyo oluxhaswa ngemali." Kule protocol exhaswa ngemali-gulane, izigulane-eziziwayo ngokugcwele ngophando nophando lwalolu hlobo lwenkqubo nge-FDA - lunokufaka isicelo ukuba lube yinxalenye yophando lokuphonononga uphando ekuhloliseni imiphumo yonyango kwizifo ezininzi ezizimeleyo , kuquka i- optic neuritis , i- rheumatoid arthritis , i- multiple sclerosis , ne- Hashimoto's thyroiditis , kunye nezinye iimeko, kubandakanywa nemiba eyahlukeneyo yomzimba, i- peripheral neuropathy , isifo se-Parkinson, isifo se- asthma nezinye izifo kunye nezimo.
Nantsi ingqwalasela yendlela inkqubo yezobugcisa isebenza ngayo. I-mini- liposuction ivelisa into eyaziwa ngokuba yi "fraction fraction" okanye i-SVF. I-SVF iqulethwe zizigidi zamaseli omntu omdala, kunye nezinye izinto zokukhula. Emva kwenkqubo yokucoca, i-SVF iphinda ifakwe kwisigulane ivunwa. Ezi zijikelezo ze-autologous stem cell - apho umnikeli kunye nommkeli abafana nesigulane esifanayo banciphisa ithuba lokugatywa, kwaye sele sele bebonisa izithembiso kwizigulane ezineengxaki ezahlukeneyo ze-thyroid kunye ne-endocrine disorders.
UJudy Richardson, oneminyaka engama-56, waseWash, e-Indiana, unzima noHashimoto's thyroiditis iminyaka emininzi. Wafunda ngonyango lwe-SVF ngokusebenzisa uphando nge-intanethi, waza wafuna udokotela kwindawo yakhe enikezela unyango. Ugqirha afunyenwe kwindawo yakhe akayiyo i-endocrinologist; ungumgqirha weplastiki, kunye neminyaka yokusebenza eyenza i-liposuctions. UDkt. Robert Jackson wezobuGcisa bobuGcisa baseHamilton eNoblesville, e-Indiana- unxulumene neCandelo loPhando lweeSelp - uRichardson kunye namaqhekeza akhe asetyenziswa ngamanqatha aphindwe kabili ngo-2013, ajobe iiseli zakhe ezivuniwe ngokuphindaphindiweyo.
"Emva kwentsholongwane yokuqala ye-IV, ndandiziva ndingcono," ukhumbula uRichardson. "Andizange ndibe nobanda bonyaka." Ngaphambili, uyachaza, "Ndade ngugqirha inyanga zonke ndifumana i-antibiotic shots.
Ndandivakalelwa kukuba ndandifuna ukufa. Amathambo ami ayebuthakathaka, ndavuka ebusuku ndikhala - andinakuze ndibeke ubunzima bam amathambo. Umlenze wam waphuma kwisiseko sawo. Oogqirha bam becinga ukuba ndandomdlavuza wesifuba. Kwakubi. Ndayeka ebomini. "
U-Richardson uthi uyaqhubeka evakalelwa ukuphucula ukususela kwisibini ye-IV ye-SVF, kunye ne-endocrinologist yakhe-uDkt. Ashok Kadambi wase-Fort Wayne Endocrinology e-Fort Wayne, e-Indiana - uthe uvuyiswe yinkqubela ye-SVF. UDkt. Kadambi wathandwa kakhulu ngenkqubela yeRichardson ukuba ucinga ukuba ngumntu osebenzisana naye kwi-Network Surgical Network Network.
U-Richardson naye unesifo sesifo sika-Addison , imeko engapheliyo yinto eqhelekileyo kwizigulane ezineHashimoto's thyroiditis. Uthi: "Amadrenal am ayenayo kakhulu ukusebenza. "Ndibe kwi-steroids, kwisilinganiso sama-milligram ezingama-20 ngosuku."
Namhlanje, ukususela kwinyanga yakhe yesibini ye-SVF, uRichardson uthi, "Ndiqhuba kakuhle kangangokuba i-endocrinologist yam isicincile kwi-steroids - ndihla nge-4 milligrams ngosuku." Ngokuphathelele imithi yakhe yokuguqula i-thyroid, uthi u-Richardson: "Ndandineminyaka eyi-120gramgram ngosuku, kodwa beye beyinciphisa ngokuqhubekayo - ngoku ndiphantsi kwezigidigidi ezingama-75."
Esinye isigulane sikaHashimoto, umfundi wasekholeji uDavis Schrader, akufuneki ukuba afune ugqirha ukuba aphathe isifo sakhe sikaHashimoto. Uyise kaDavis nguDkt. Lawrence Schrader we-Schrader Orthopedics kunye neSikhungo seStem Cell Treatment Centre eCordova, eTennessee.
Ngethuba lokuqeqeshwa kunye nokuvunyelwa kwiziko laseCalifornia Stem Cell Treatment Centre, kwaye ngaphambi kokuba abe ngumbutho weCandelo loPhando loLuntu ngo-2012, uDkt. Schrader ngokwakhe wafumana unyango lwe-stem ye-stem ukuze anciphise ubuhlungu obungapheliyo emagxeni akhe kunye ne-meniscus yakhe eyiyo.
Ngaloo ndlela uDavis, unyana wakhe endala, wafumanisa ukuba uneengxaki ezahlukeneyo zempilo ngelixa esesikolweni esiphakeme. Ngokutsho kukaDkt. Schrader: "Unomdlali obalaseleyo, umdlali webhola yebhola, kodwa kwakubonakala ngathi unokufumana isifo se-asthma okanye ingxaki yentliziyo. Wayehlala ephefumlelwe, kwaye wayebonakala elahlekelwe ngumonde. ukukhangela, kwaye i-thyroid yayiphantsi kwaye yavavanya i-Hashimoto. Ngoko ugqirha wakhe wambeka kwi- Armor ye-thyroid . "
Ngomnyaka olandelayo, xa uDavis ehamba ekolishi, uyise uyakhumbula: "Kwakubonakala ngathi unenkxalabo yokulala nokugxininisa, kwaye wayevakalelwa nje esicinekile kwaye ehlaseleyo. Kwafuneka sikhuphe ngaphandle kweemester kuba wayengenayo yokwenza unyango. "
Ngelo xesha, uSrrader wagqiba ekubeni azame ukuphazamisa unyango lweseli kumntwana wakhe. Unomdla ngolu hlobo lwezonyango owake wafunda ngazo ngeprotomodulatory property of cell stem cells, uSrader wanika unyana wakhe i-SVF yokufakelwa kwe-IV. Namhlanje, ubaba oqhoshayo uthi, "Mhlawumbi ama-80-90 ekhulwini angcono. Wabuyela esikolweni waza waphela i-semester ene-B ephakathi!"
IINKCUKACHA EZITHE XAXE
Olu unyango lubhekwe uphando. Unokufunda ngokubanzi malunga neli ganga lonyango kunye ne-FDA apha.
Ayikho yonke i-thyroid okanye isigulane se-endocrine-okanye abo banezinye iimeko eziphathwe nge-SVF - ngumviwa ofanelekileyo kulo nyango. Kwaye ngoku, xa kunikwa unyango lophando, i-inshorensi ayisoloko ifihla iindleko, yintoni eyenza unyango luxhaswa ngemali.
Kodwa kulabo abanomdla ekuhloliseni olu unyango olungundoqo, isinyathelo sokuqala esihle kukuqhagamshelana nomnye wezilwanyana onyilungu leNgcaciso yokuThengwa kweSeli kwaye owaziyo nge-SVF / stem yonyango. Ukufumana inkcazo ecacileyo kunye ephosakeleyo yesiphelo se-autologous stem cell transplant, esaphilisa isifo sika-Julia Szabo esibangelwayo isifo sesifuba - kunye ne-osteoarthritis yenja yakhe-ndincoma ukuba ndifunde incwadi yakhe: Inja yeMithi: Inyango Yommangaliso Ephilisa Umhlobo Wam Omhle Yaye ndasindisa Ubomi Bam.