Ulungelelaniso lweDose Ulungiso olungafunekayo ukuze kuqinisekiswe iMpilo ye-Fetal
Ingubo yakho ye-thyroid ibalulekile ngexesha lokukhulelwa njengoko lilawula ukuveliswa kwamahomoni okuthiwa i-triiodothyronine (T3) kunye ne-thyroxine (T4), elo elo lidlala indima ebalulekileyo ekuphuhlisweni kwengqondo yengane kunye nenkqubo yesifo.
Ngexesha lokuqala kwe-trimester, umntwana usuxhomekeke ekunikezeni umama we-hormone ye-thyroid, ekhutshwa kwi-placenta.
Ukuze uhlangabezane nale mfuno, ukuveliswa kwe-thyroid yowama ngokuqhelekileyo kuya kwi-overdrive, okubangele ukwandiswa kwethambo ngokwalo. Oku kuvame ukuphawulwa kwaye akuyi kuba nzima ukukhulelwa nangaliphi na indlela.
Nangona kunjalo, kwezinye iimeko, ukwandiswa kungabonakala kwiimviwo zekliniki kwaye umcebise ukuba loo mfazi unesifo se- hypothyroidism , imeko apho i-thyroid gland ayivelisi i-hormone ye-thyroid eyaneleyo.
Ukutshintshwa komsebenzi we-Thyroid ngexesha lokukhulelwa
Ngaphandle kweemeko eziqhelekileyo, ukukhulelwa kubeka uxinzelelo kwi-thyroid gland. Isidingo sokwandisa imveliso ye-hormone ngamaphesenti angaphezulu kwama-50 kuya kubangela ukuba kwandiswe i-gland ngokwayo. Kubasetyhini abanomsebenzi oqhelekileyo we-thyroid, i-gland inokunyuka ngama-10 ekhulwini ngobukhulu. Kubasetyhini abane-hypothyroidism, kunokunyuka ngamanye ama-20 ukuya kuma-40 ekhulwini.
Ngaphandle kwandiso lomzimba ngokwalo, kukho utshintsho kwimveliso ye-hormone oogqirha abanako ukubeka iliso ngokusebenzisa iimvavanyo zegazi.
Oyintloko phakathi kwabo nguvavanyo lwe-TSH, olulinganisa izinga le-hormone ye-thyroid (stimulating hormone) egazini. I-TSH yi-hormone eveliswa yi-pituitary gland edala ukuveliswa kwe-T3 kunye ne-T4.
Ngenxa yokuba umsebenzi oqhelekileyo we-thyroid uhlukile ngexesha lokukhulelwa, ixabiso le-TSH liya kutshintsha njengoko unina uqhubeka ukusuka kwi-trimester yokuqala ukuya kweyesithathu.
Kwiimeko eziqhelekileyo, ixabiso eliqhelekileyo le-TSH liza kusuka kwi-0.2 ukuya kwi-4.0 mlU / L.
Ukuba nangona nayiphi isizathu i-thyroid igland ayikwazi ukuqhubeka ngexesha lokukhulelwa, ixabiso liya kulahla, ebonisa isimo se-hypothyroid. Kwimeko enjalo, iyeza le-hormone ye-substituted substitute will be prescribed for replacing the hormone ye-thyroid. Umama uya kuthi ahlolwe rhoqo ukuvavanya ixabiso le-TSH, ukulungiswa kwonyango njengoko kuyimfuneko.
Ukujonga i-TSH ngexesha lokukhulelwa
Ama-laboratories amaninzi afaka iiferensi zazo zee-TSH ezichazwe ngokuthethelekileyo ngezinto ezicinga ukuba zixabiso "eziqhelekileyo" kwisigaba ngasinye sokukhulelwa. Ukuba akunjalo, i-American Thyroid Association (ATA) icebisa ukusetyenziswa kwezi zilandelayo:
- I-trimester yokuqala: 0.1-2.5 mIU / L
- I-trimester yesibili: 0.2-3.0 mIU / L
- Iyesithathu ezintathu: 0.3-3.0 mIU / L
Ukuba unesifo se-thyroid, kufuneka uhlolwe rhoqo ngexesha lakho lokukhulelwa . Ukuba isifo se-thyroid siqhuba kwintsapho yakho okanye unempawu zesifo, kubalulekile ukuxelela ugqirha wakho ukuze ulandelwe kakuhle kwaye uphathwe.
Hypothyroidism
Ukuba u-hypothyroid, kubalulekile ukuba uphathwe kokubili nangaphambi kokukhulelwa kwakho. Ukuba ushiywe ungaphendulwanga okanye ungaphathi kakuhle, i-hypothyroidism yakho ingabangela iingxaki zentuthuko kunye neenjini kumntwana wakho.
Ukuba uphathwa nge-hypothyroidism, ungacingi ukuba unokuqhubeka nokulawula imeko yakho ngendlela efanayo. Unokwenene ukwandisa umlinganiselo wakho wee -hormone zee -hormone zokutshintshwa kwezidakamizwa ngama-50 ekhulwini ngokukhawuleza xa ukhulelwe. Enyanisweni, uphando lubonisa ukuba ama-50 ukuya kuma-80 ekhulwini ekhulwini labasetyhini baya kufuna ukwenza oku.
Ngokwezikhokelo ze-ATA, oku kunyuka kufuneka kuqale ekuqaleni kweveki 4 ukuya ku-6 kwaye uqhubeke ukuya kwiiveki ezi-16 ukuya kwe-20 (emva koko umsebenzi wakho we-thyroid uza kufakwa kwi-plateau kude kube kuthunyelwa).
Ngokubhekisele kweso esweni, iimvavanyo ze-thyroid ziya kufuneka ziqhutywe nganye kwiiveki ezine kwisiqingatha sokuqala sokukhulelwa kwaye kwakhona kwakhona phakathi kweveki 26 no-32.
Ukulandela ukuhanjiswa, amachiza amachiza aya kufuneka adityaniswe kumanqanaba okukhulelwa kwangaphambili kunye nokubeka iliso ngokulandelelanayo kwenziwe emva kweiveki ezintandathu emva komhla wokuhambisa.
Izifo zikaHashimoto
Isifo sikaHashimoto , esaziwa ngokuba nguHashimoto's thyroiditis, sisifo esizimelayo esihlasela kwaye ngokukhawuleza sitshabalalisa i-thyroid gland. I-Hypothyroidism iqhelekileyo isiphumo sengxaki kwaye iphethwe ngendlela efanayo ngokusebenzisa i-hormone yonyango yokuguqula.
Ukunyangwa kwesifo sikaHashimoto ngexesha lokukhulelwa kubandakanya ukuphatha i-hypothyroidism, nangona kufuneka kwenziwe ingqalelo engakumbi yokugcina i-TSH phantsi kwe-2.5 mlU / L, njengoko amanqanaba aphezulu anxulumene nokunyuka kokuphindwe kabini kwengozi yokukhulelwa kwesisu.
Izifo zeMangcwaba
Kwezinye iimeko, ibhinqa lingahle lisebenze kakubi kunokuba i-thyroid engasebenzi. Oku kwaziwa ngokuba yi-hyperthyroidism, edlalwa rhoqo yiSifo seMangcwaba .
Ukuba ishiywe ingaphendulwanga, i-hyperthyroidism ingakhokelela ekuzalweni kwangaphambi kokuqala okanye kwi-preeclampsia (ukukhulelwa kwengxaki ebonisa ukunyanga kwegazi kunye nomonakalo wembutho). Izingozi kumntwana ziquka ubunzima bokuzalwa obuphantsi, isantya senhliziyo esiphuthumayo, iimpembelelo zesisu, kunye nezinye iinkxalabo zempilo. Kwiimeko ezinzima kakhulu, unokubeletha.
Ukongezelela, ukuba ukhulelwe kwaye unesi sifo se-Graves, unomngcipheko okhulayo wokuphuhlisa uhlobo olubi lwe-hyperthyroidism ebizwa ngokuba sisiqhwithi se-thyroid . Eyaziwa ngokuba yingxaki ye-thyrotoxic, kubangelwa ukukhululwa okwedlulele kwee-hormone ze-thyroid ezibangele ukwanda kwenyani kwixinzelelo legazi, ukushisa komzimba kunye nentliziyo yezinga.
Ngethuba lokukhulelwa, isifo se-Graves sisiphathwa ngonyango lwe-antithyroid ebizwa ngokuba yipropylthiouracil ngexesha le-trimester yokuqala kunye nelinye libizwa ngokuba yi-methimazole kwisisele eseleyo.
ILizwi
Into ebalulekileyo ukuba uyikhumbule kukuba ukuba u-hypothyroid kwaye uceba ukukhulelwa, kufuneka uxoxe nodokotela wakho malunga nokulungiswa kwemilinganiselo yakho ye-thyroid ye-hormone yokuguqula imithi ukuze ulungise ukuzala. Injongo kukugcina izinga lakho le-TSH ngaphantsi kwe-2.5 mIU / L.
Kufuneka usebenze kunye nogqirha wakho ukuqinisekisa ukukhulelwa kwakho ngokukhawuleza, kwaye ube nesicwangciso endaweni ukuze ukwandise umlinganiselo wakho weyeza ngamayeza esetyenziswe kwangaphambili ngokukhawuleza kwakho ukukhulelwa.
> Umthombo:
> Alexander, E; Pearce, E .; Brent, G; et. al. "2017 Izikhokelo ze-American Thyroid Association ye-Diagnosis kunye noLawulo lweZifo zeTyroid ngexesha loKhulelwa kunye nePostpartum." I- Thyroid. 2017; 27 (3): 315-389.