I-Wine Wine Antioxidant Kwangathi Impembelelo yeTesttosterone neNqanaba le-Insulin
I-Resveratrol, i-antioxidant efunyenwe eluswini lweidiliya , amajikijolo, iwayini ebomvu kunye neepanantisi ibonise iziphumo ezikhuthazayo zokunceda ukubuyisela ibhalansi ye-hormone kunye nokuzala kubasetyhini abane-polycystic ovary syndrome (i-PCOS), ngokutsho kwiphononongo epapashwe kwi- Endocrine Society's Journal Endocrinology Clinic & Metabolism.
Abafazi abane-PCOS banamanqanaba aphezulu amahomoni angamadoda, njenge testosterone, kunye namazinga aphakamileyo e-insulin, enokubangela ukungabikho kwintsholongwane kunye nohlobo lwe-2 lweswekile.
Ionyango zeMveli zePCOS zibandakanya ukutya kunye nokuguqulwa kwendlela yokuphila , i-insulin yokuvuselela imishanguzo, ukulawulwa kokuzalwa, kunye nokuvelisa i-ovulation. Uphando kwiindima ezithile zokuncedisa ukutya, njenge-resveratrol, sele iqalile ukufumana ingqalelo ngakumbi njengokuba abafazi abane-PCOS bafuna ukhathalelo olukhuselekileyo kunye nonyango olongezelelweyo ukuphucula imeko yabo.
Ukuphulukana neSifundo
Kuhlolisiso, izigulane ezingama-30 ezine-PCOS zanikelwa ngenyameko okanye i-resveratrol supplement (1,500 mg) okanye ipilisi ye-placebo yonke imihla yeenyanga ezintathu. Abafazi babephethe iisampula zegazi ezithathwe ngamazinga e-androgen we- testosterone kunye ne-dehydroepiandrosterone sulfate (DHEAS), umcebisi we-testosterone, ekuqaleni nasekupheleni kokufunda, kunye nokuhlolwa komlomo we-glucose ukunyamezela ukufumana nayiphi na ingozi yemofu ye-diabetes.
Iziphumo zophando zazikhuthaza kakhulu. Abasetyhini abafumana isongezelelo se-resveratrol babone ukunciphisa ama-23 ekhulwini kwizinga lazo zonke ze-testosterone kunye nokunciphisa iipesenti ezingama-22 kwizinga le-DHEA sulfate.
Ezinye iindaba ezilungileyo kukuba abafazi abanikwa i-resveratrol baphucula amanqanaba abo e-insulin. Enyanisweni, ukuzila ukutya kwe-insulin kwamanqanaba angama-32 eepesenti kwisifundo seenyanga ezintathu.
Yintoni oku kuthetha ngayo kuwe
Ngokuqhelekileyo, i-resveratrol yaziwa ngokuba yi- anti-aging , i-antiticancer kunye nepropatiotropact properties.
Zityebi kwiipolphenol kunye ne-antioxidants, i-resveratrol iboniswe ukuba inokukwazi ukulwa nokuvuvukala kunye nokunciphisa i-cholesterol kunye ne-insulin kwezinye iindawo. I-Resveratrol kwiwayini ebomvu icetyiswa ukuba yimfihlo kwi "French Paradox," isizathu sokuba abantu abahlala eFransi babe namazinga aphantsi esifo senhliziyo naphezu kokutya okutya okuninzi okuninzi (okubandakanya kakhulu ushizi kunye nebhotela) kunye namazinga aphezulu okutshaya .
I-Resveratrol inokuphumelela ekuphuculeni ukuzala ngokuphucula umgangatho weqanda (oocyte) kunye nokukhula komzimba, ezo zombini ezinokuthi zingancinci kwabasetyhini abane-PCOS.
Kodwa phambi kokuba ungayibhokisi i bhotile ye-cabernet, yazi le nto: inani le-resveratrol kwisifundo se-PCOS yayingu-1,500 mg imihla ngemihla, okulingana nokusela phakathi kwe-100 ukuya kwi-200 ilitha yewayini ngosuku. Oku bekuyiyokuqala ukuphonononga iingenelo ze-resveratrol kubasetyhini abane-PCOS kunye nezifundo ezininzi ezifunekayo ukubonisa izibonelelo zayo kunye ne-dosing efanelekileyo. Izifundo zezilwanyana zangaphambili ezibandakanya iigundane zafumanisa ukuba i-resveratrol yaphucula i-androgens, i-insulin, i- leptin kwaye yabangela ukulahleka kwesisindo.
I-Resveratrol yehlulekile ukunciphisa i-insulin, isisindo, i-cholesterol, okanye abenzi bokuvuvukala kwilingo leenyanga ezi-6 ezipapashwe kwi- Pharmacological Research, ekhupha abantu abane-type 2 yeswekile.
Kubalulekile ukuba kuqwalaselwe ukuba olu phofu lusetshenziselwa i-resveratrol (i-400-500 mg ngosuku ngokuqhathaniswa no-1500 kwi-PCOS study).
I-Resveratrol: Yintoni Oyaziyo
Uphando lwe-resveratrol luyakunyamezela. Ingozi kubafazi abakhulelweyo okanye kwiintsana e-utero aziwa. Ukusebenzisana nezinye izongezo okanye amayeza ahlale engacacanga. I-Resveratrol ezongeziweyo ezithengiswa kwiivenkile zithengwa kwaye zithengiswa ngamanani angaphantsi kakhulu kunezinto ezisetyenziswe kwi-PCOS.
Kuze kubekho uphando olongezelelweyo olubandakanya i-resveratrol ne-PCOS ekhoyo, kukho ezinye izongezelelo zokutya eziye zabonisa ukuxhamla abafazi nge-PCOS kuquka ioli yeentlanzi, i-vitamin D, i -acetylcysteine , kunye ne-myo ne-d-chiro inositol.
Ngokuqinisekileyo, akukho ncediso yindawo yokutya e- PCOS enempilo enokuthi ifake ukutya okuninzi okunokutya okunokwenziwa yi-antioxidant efana neerries, iidiliya, kunye neentonga, ukutya okufanayo ngokuqhelekileyo okuqukethe i-resveratrol.
> Imithombo:
> Bo S. Iinyanga ezithandathu zokuncedisa i-resveratrol ayinayo imiphumo enokulinganiswa kwilungu 2 izigulane zesifo sikashukela. Iilingo ezilawulwe ngokungahleliyo, ezimbini, ezingabonakaliyo. Pharmacol Res. 2016 Sep; 111: 896-905.
> Beata Banaszewska et al. Iimpembelelo zeReveratrol kwi-Polycystic Ovary Syndrome: I-Trial-blind, i-Randomized, i-Placebo-Controled-Trial Trial. J ClinEndocrinol Metab 2016; 101: 3575-3581.
> Ortega I, Duleba AJ. Iimpawu ze-ovariya ze-resveratrol. 2015; Ann NY Acad Sci.Aug; 1348 (1): 86-96.