Uphando lubonisa ukuba phakathi kwama-20% kunye no-40% wabantu abanesifo se- Parkinson (PD) baxhamla kwi-constipation enkulu (ngaphantsi kweentsuku ezintathu zokuhamba ngeveki). Inani elininzi labantu abane-PD baye baxubusha imiba yesisu njengento yokuqhaqhabalalisa, ukuvakalelwa nokuzaliswa kwesisulu. Njengoko eso sifo siyaqhubeka, zonke iingxaki ze-GI ziba zixhaphake. Kwiimeko ezinqabileyo, iingxaki ezinzulu-ezifana ne-megacolon (ukwandiswa kwekoloni) kunye nokugqithwa okanye ukugqithwa kwe-colon - kunokuvela kwiingxaki ze-GI.
Unxibelelwano phakathi kwezi zibini lungabonakala lingaqondakali phezulu, kodwa uphando lubonakalisa ukukhanya okule miphumo engathandekiyo yesifo.
Uphando olukhulu lwabantu abasempilweni abaye balandelwa kwiminyaka emininzi (njengenxalenye ye-Honolulu Heart Study Program) yabonisa ukuba amadoda anika ingxelo yokuba neentshukumo ezingaphantsi kweyodwa intshukumo yemihla ngemihla ayenamaxesha angaphezu kwama-2 ukuya kuma-7 angaphezulu kwengozi yokuphuhlisa i-PD kunokuba yamadoda behamba imihla ngemihla; umngcipheko wabo wawunexesha eliphindwe kane kuneloo madoda ayenamabhinqa amabini okanye amaninzi ngosuku.
Eli dimbi lwedatha liye lakhokelela abanye ukuba batyathele ukuba ukumbombola kukubonakalisa kwangaphambili kwenkqubo yesifo kwaye kungaphambi kweempawu zePD ngeminyaka. Ubudlelwane obangelwayo kunye nobudlelwane phakathi kokuqhawulwa kunye nePD luphandwa ngokuphandle. Enye imbono ebonisa ukuba indima ebangela ukunyanzelisa ekuphuhlisweni kwe-Parkinson kukuba ukuba izinto ezihamba ngokuthe ngcembe kwikholoni, nayiphi na into enetyhefu etyunyiwe inokuthi ixhomekeke kwinkqubo.
Xa sele ixutywe ngobuninzi, izinto ezinobungozi zingonakalisa iiseli ezenza i- dopamine , ukubeka umntu kumngcipheko omkhulu we-Parkinson. Nangona kunjalo, kubantu abaye bafumanisa ukuba banesi sifo, ukungabikho kwamanani okwaneleyo we-dopamine kunokuchaphazela ngqo imisebenzi yesisu (GI), ukunciphisa ukuhamba kwezinto eziphathekayo kwi-colon.
Yintoni Enokwenziwa Ngalezi Zingxaki Zengxaki ze-GI?
Ngelishwa, uphando olwenziwa kwiingxaki ze-GI ezihlobene nePD zimbalwa kwaye ziphakathi, ngoko ke oogqirha abanalo naluphi na iindlela zokuzama nokunyanisekileyo zokujongana nazo. Ezinye zamachiza ukuphatha iingxaki ze-GI kubantu abangenazo i- PD abanako ukusetyenziswa kulabo abanePD kuba leziyobisi (i-Metoclopramide hydrochloride) ifuthe kakubi kwiinkqubo ze-dopamine kwingqondo.
Ukuba unePD kunye nokuvalelwa kwamava, kunengqondo ukuzama ukusebenzisa iindlela ezikhuselekileyo nezilula ukujongana nale mbambano ngaphambi kokuba ungeze iziyobisi ezintsha kwi-regimen yakho yemihla ngemihla. Ukwandisa i-fiber yokutya kunye nokusela kwamanzi amaninzi kunye nezinye izixhobo zamanzi ziyinyathelo lokuqala elifanelekileyo lokunyango. Ukuba ugqirha wakho uyayivuma, unokucinga ukuba uthatha izongezelelo zefiber, ezifana ne- psyllium okanye i- methylcellulose . Ukuba ezi zindlela ezilula azisebenzi, ugqirha wakho unokucinga ukuba ukunika isilathisi se-stool okanye i-laxative.
Umthombo:
I-Pfeiffer, i-RF (2005) I-Intestinal Dysfunction. Ku: Izifo ze-Parkinson kunye nokungasebenzi komsebenzi ongekho. URF Pfeiffer kunye no-I. Bodis-Wollmer, u-Eds Humana Press: UTotowa, eNew Jersey, i-Pps 115-126.