Kubantu abathathu kubantu abane abahlakulela isifo seParkinson (PD), eso sifo siqala ngokuthuthumela okanye ukuthuthumela kwelinye yezandla. Inokubonakala kwakhona kwiinyawo, ubuso, okanye umhlathi kodwa ngokuqhelekileyo, ibonakala kwesinye sezandla. Oku kunyikima kwenzeka xa izihlunu zezandla zikhululekile kwaye ziphumle. Ngenxa yoko igama: ukuphumla.
Ukugubha kunomgangatho 'wePill-Rolling'
Ingqungquthela ibonakala ngathi uqhuma ugwayi, uhlamvu lwemali, okanye ipilisi phakathi kwesithupha sakho kunye nesicatshulwa somunwe.
Yingakho kuthiwa yi-"pilill-rolling".
Yintoni Edala Ubungangamsha?
Iingcali zenzululwazi azikazisombululi imfihlelo yezinto ezibangela ukugubhazela kodwa zineenkcukacha ezilungileyo.
- Esinye sezizathu ezibalulekileyo zesifo sika-Parkinson kukulahleka kwe- dopamine kwimimandla yengqondo exhasa ukunyakaza.
- Ezi ndawo zengqondo ezihambelana nokunyakaza ziququzelelwe kwiisekethe ezenzelwe ukuvelisa iintlobo ezahlukeneyo zokuhamba.
- Esinye salezi zijikelezo siquka indawo yokulawula ingqondo ebizwa ngokuba yi-thalamus.
- I-thalamus inceda ukulawula ukunyakaza ngokudlulisela ulwazi olusisiseko malunga nokuhamba ukusuka kwiintsingiselo ukuya kwiingqondo. Ingqondo isebenzisa le "ngxelo yengqondo" evela kwi-thalamus ukulawula ukuhamba okuhambelanayo.
- Ukulahlekelwa kwe-dopamine kwisekethe yengqondo ephethe i-thalamus iphazamisa ukusebenza kwethalamus.
- Izifundo ezininzi zibonise ukuba ukuwa kwizinga elipheleleyo le-dopamine kwisiphaluka se-thalamic kuqala iminyaka ngaphambi kokuqala kokuthuthumela kunye nePP.
- Xa amazinga e-dopamine afinyelela kwizinga eliphantsi kakhulu, i-thalamus ilahlekelwa yimpembelelo yayo evamile kunye nokuthuthumela.
Xa ingqondo ingenakufumana ingxelo echanekileyo malunga nendlela ukuhamba kakuhle kuqhubela phambili, akunakukwazi ukulungisa ngokunyanisekileyo ukunyakaza okanye ukulungelelanisa ukunyakaza okucothayo njalonjalo.
Iimpawu ezinzima kakhulu, ezifana nokunyakaza kweminwe nezandla, ziyokuqala ukuchaphazeleka, kwaye zichaphazeleka kakhulu.
Inketho yokwenza unyango engcono yokuphumla ukutshatyalaliswa kuseyi-dopamine yonyango yokutshintshwa.
Imithombo:
> ISikole kaZwelonke seNational and Disorders and Stroke. "Izifo ze-Parkinson: Ithemba Ngophando." http://www.ninds.nih.gov/disorders/parkinsons_disease/detail_parkinsons_disease.htm
> R. Pahwa kunye no-KE Lyons (Abahleli), IsiXhosa seZifo zePasinson ; I-4 Edition, eNew York, Abashicileli bezeMpilo kwi-Informa, ngo-2007.