Yintoni Okufanele Ndiyazi Ngayo?
I-Aniracetam luhlobo lwe-nootropic, iklasi leziyobisi ezisetyenziselwa ukuqinisa umsebenzi wengqondo. Nangona i-aniracetam iyatholakala njengemithi yesigqirha eYurophu, okwangoku ayilawulwa phantsi eMelika.
Ukusetyenziswa kweAniracetam
Ukuchonga njengesixhobo esiyingozi, i-aniracetam isetyenziswe kwilinye iyeza ukuze kuphuculwe imemori, kuphuculwe ingqalelo kunye nokwandisa ukuphaphazeka kwengqondo.
Ukongeza, i-aniracetam ngamanye amaxesha isetyenziswe kule miqathango ilandelayo:
- Isifo se-Alzheimer
- ingqalelo yokungaphumeleli kokugula
- uxhalaba
- ukuxinezeleka
- ukugula
- izifo zokulala
I-Aniracetam iphinda ibekwe njenge-agent anti-aging.
Izinzuzo zeAniracetam
Nangona izilingo ezimbalwa zeklinikhi ziye zavavanya iziphumo zempilo ze-aniracetam, iindidi zezifundo zokuqala zibonisa ukuba i-aniracetam inokubonelela ngezibonelelo ezithile zezempilo.
Ngxelo epapashwe kwiphepha le- CNS Izidakamizwa zeeDrug ngo-2002, umzekelo, abaphandi bahlalutya uphando olukhoyo malunga nokusetyenziswa kwe-aniracetam kwonyango ye-nervous system (CNS) kunye nezifo. Ukukhangela iziphumo ezivela kwizifundo ezisekelwe kwizilwanyana, abaphandi bafumanisa ukuba i-aniracetam ibonisa isithembiso ekulawulweni kweemeko ezinjenge-post-disinstration disorder, i-autism, kunye nokuphazamiseka kokulala. Nangona kunjalo, ababhali bembali bathi "akukho ubungqina obukholisayo" bokusebenza kwe-aniracetam ekuphatheni nayiphi na le miqathango kubantu.
Nanku ukukhangela kwezinye iziphumo eziphambili ezivela kwiziphumo ezikhoyo kwi-aniracetam:
1) Ukuxhalabisa
I-Aniracetam inokunceda ekwenzeni ukuphazamiseka kwezixhala, ngokwe-2001 eyayishicilelwe kwi- European Journal ye-Pharmacology . Kwiimvavanyo kumagundane, abaphandi bafumene ukuba i-aniracetam inokunceda ekunciphiseni ukuxhalabisa ngokuchaphazela inani leenqwelo-mzimba (iklasi leemichiza ezibandakanyekayo ekuthwaleni imiyalezo esuka kwiiseli zesiswini ukuya kwezinye iiseli).
2) Ukudandatheka
I-Aniracetam inokuba nempembelelo enjenge-antidepressant-like-effects, ukufundisisa ngo-2001 kwincwadi ye- Psychopharmacology icetyiswa. Kwiimvavanyo kwierats, izazinzulu zifumene ukuba i-aniracetam inokunceda ekuvuseleleni i-dopamine (i-neurotransmitter efunyenwe kumazinga aphantsi kubantu abanexinzelelo).
3) Ukukhubazeka kwengqondo
Izifundo eziliqela zokuqala zibonise ukuba i-aniracetam inokuba yinzuzo ethile kubantu abanokukhubazeka kwengqondo. Ngokomzekelo, uphando olwenziwe ngo-2012 olupapashwe kwi- CNS Neuroscience & Therapeutics luboniswe ukuba unyango lwabantu asebekhulile nge-aniracetam lonyaka lukhokelela ekuphuculeni okubonakalayo ekusebenzeni kwengcamango. Ukubandakanya abantu abadala abangama-276 abaneengxaki zengqondo, uphando lufumanise ukuba i-aniracetam inemiphumo ebalulekileyo kwimvakalelo kunye nempilo enempilo.
Ukongezelela, uphando olusekelwe kumatshini olupapashwe kwi- Psychiatry and Clinical Neurosciences ngonyaka ka-2000 lufumene ukuba i-aniracetam inokukunceda ukuphatha ukuphazamiseka kokulala okuhlobana nomqondo wokugula ngengqondo .
Imijelo
I-Aniracetam inokubangela inani lemiphumo emibi, kuquka ukulala , ukuphathwa kwentloko , ukuxhalaba, intlungu , i-vertigo, i-nausea, kunye nehudo .
Ngenxa yokungabikho kophando, encinci iyaziwa malunga nokukhuselwa kokusebenzisa i-aniracetam. Kubalulekile ukugcina engqondweni ukuba izongezelelo azange zivivinywe ukukhusela kunye nezondlo zokutya zikhululekile.
Kwezinye iimeko, loo mveliso inokuhambisa amaxabiso ahluke kwixabiso elichaziweyo kwiyeza ngalinye. Kwezinye iimeko, loo mveliso inokungcoliswa nezinye izinto ezifana nezitye. Kwakhona, ukhuseleko lwezongezelelo kubasetyhini abakhulelweyo, oomama abangabongikazi, abantwana, kunye nalabo abanezifo zonyango okanye abathabatha imishanguzo ayilwanga. Unokufumana amanye amathiphu ekusebenziseni izongezo apha .
Kuphi Ukuyifumana
I-Aniracetam iyafumaneka ngokubanzi ukuthengwa kwi-intanethi.
Ukusebenzisa i-Aniracetam yezeMpilo
Ngenxa yophando oluncitshiswayo, kungekudala ukucebisa i-aniracetam nayiphi na injongo yezempilo. Kwakhona kubalulekile ukuba uqaphele ukuba ukuzinyamezela ngesifo esingapheliyo kunye ne-aniracetam kunye nokuphepha okanye ukulibazisa ukunakekelwa okuqhelekileyo kunokuba nemiphumo emibi.
Ukuba uqwalasela ukusebenzisa i-aniracetam, qiniseka ukuba udibane nodokotela wakho ngaphambi kokuwusebenzisa.
Imithombo
UKimura M, Okano S, Inoué S. "Iimpembelelo ze-aniracetam kwiindlela zokulala ezingekho kakuhle kwi-rhythme-prone one-rats hypertensive rats." I-Psychiatry Clinic Neurosci. 2000 Juni; 54 (3): 314-6.
I-Koliaki CC, i-Messini C, i-Tsolaki M. "I-aniracetam esebenzayo ngonyango, nokuba yi-monotherapy okanye ihlanganiswe ne-inlinesite ye-cholinesterase, kwizigulane ezinokukhubazeka kwengqondo: ukufundiswa okuvulekileyo." CNS Neurosci Ther. 2012 kuMatshi; 18 (4): 302-12.
Li Y, Wang JJ, Cai JX. "I-Aniracetam ibuyisela imiphumo yeprotheni ye-amyloid-beta okanye ukuguga kwi-membrane fluidity kunye ne-intracellular concentration ye-calcium kwi-synaptosomes yamagundane." J Neural Transm. 2007; 114 (11): 1407-11.
I-Nakamura K. "I-Aniracetam: inomxholo wayo wezobulali ezinokubangela izifo ezingasebenzi ngokubhekisele kwizinto ezifunyenwe ngokutsha kwamachiza." I-CNS iDrug Rev. 2002 Spring; 8 (1): 70-89.
Nakamura K, Pageswa M. "Iimpembelelo ze-aniracetam kwiimpawu ezintathu ezihlukeneyo zemouse ezixhalabileyo kunye neendlela ezisisiseko." Eur J Pharmacol. 2001 Meyi 18; 420 (1): 33-43.
Nakamura K, Tanaka Y. "Iziphumo ezinjenge-anti-depressant ezifana ne-aniracetam kwiimbophu ezindala kunye nendlela yokusebenza kwayo." I-Psychopharmacology (Berl). 2001 Nov; 158 (2): 205-12.
Ukuziphendulela: Ulwazi oluqulethwe kule ndawo lujoliswe kwiinjongo zemfundo kuphela kwaye alithathi indawo yeengcebiso, ukuxilongwa okanye unyango ngumgqirha onelayisenisi. Akunakuthetha ukukhusela zonke iindlela zokulondoloza, ukusebenzisana kwezidakamizwa, iimeko kunye nemiphumo emibi. Kufuneka uncede unyango lwangonyango ngokukhawuleza kuyo nayiphi na imiba yempilo uze ubonane nodokotela wakho ngaphambi kokusebenzisa elinye iyeza okanye wenze utshintsho kwi-regimen yakho.