Izinto ezili-7 omele uziphephe Ukuba unako ukukhubazeka kwe-G6PD

I-Glucose 6 I-Phosphate Dehydrogenase (G6PD) ilahleko yintlobo yefa le-hemolytic anemia , uhlobo lwe-anemia eyenzekayo xa iiselom zegazi ezibomvu zityhulwa ngokukhawuleza kunokuba ziqhelekileyo (oku kuthiwa yi- hemolysis ). Kule ntlupheko ye-G6PD eyenzekayo ngenxa yokuba wenza inani elincinci le-G6PD, i-enzyme ekhusela iseli elibomvu legazi kumonakalo. Ngenhlanhla, uninzi lwabantu abane-G6PD abangenayo ingxaki imihla ngemihla. Nangona kunjalo, kukho imithi ethile okanye ukutya okwandisa izinga lokutshatyalaliswa kweeseli ezibomvu zegazi. Masihlole ezinye zezinto eziqhelekileyo ezingabangela iingxaki kule ngxaki yegazi.

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Antibiotics

Abantu abanokukhubazeka kwe-G6PD banokunyamezela amaninzi amagciwane kodwa kufuneka baqaphele abambalwa abakhethiweyo abangakwazi ukuqala ukuphazamiseka kweeseli ezibomvu zegazi ezikhokelela ekubeni negazi. Amayeza okubizwa ngokuba yi "sulfa" kufuneka aphetshwe. Ezi antibiotics zisetyenziselwa ukuphatha unyango okanye i-urinary tract (bladder). Ifomu eqhelekileyo yale mithi ye-antibiotics ihamba ngegama legama le-Septra okanye iBactrim (sulfamethoxazole-trimethoprim).

I-anti-antibiotic "quinolone" kufuneka ikhutshwe. Amachiza amabini aqhelekileyo kwiiqela liyi-Cipro (ciprofloxacin) kunye neLevaquin (levofloxacin). Ezi antibiotics zisetyenziselwa abantu abadala ukuba baphathe izifo zokugonywa kwamanzi kunye ne-pneumonia. Ezinye iziza-antibiotics ezimele zigwenywe ziquka nitrofurantoin kunye ne-dapsone.

Ngethamsanqa, kukho ezininzi antibiotics ukuba abantu abane-G6PD abangakwazi ukukhusela. Qinisekisa ukuxubusha oku kunye nodokotela wakho ukuba unesifo se-G6PD kwaye ufuna i-antibiotic therapy.

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IMelaria

I-Primaquine, iyeza elisebenzisa ukuphatha okanye ukukhusela i- malariya , lingabangela ukuhlupheka kwe-hemolytic kubantu abane-G6PD. Ngenxa yolu ngxaki, kunconywa ukuba abantu bavavanywe ukusilela kwe-G6PD ngaphambi kokuthatha i-primaquine. Oku kubandakanya abantwana abancinci abanomama abazithatha i-primaquine. Ngethamsanqa, ezinye iimyeza ezisetyenziselwa unyango lwe-malaria ziyaxhaswa ngabantu abaninzi abane-G6PD.

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Amachiza asetyenziswa kwiCreatcer Treatment

I-Rasburicase yonyango esetyenziselwa ukuphatha i-tumor lysis syndrome, ingxaki yezokwelapha ye-hematologic khancer efana ne-leukemia, ayifanele isetyenziswe kubantu abane-G6PD. Ngenxa yengozi, kucetyiswa ukuba abantu bavavanywe ngaphambi kokufumana i-rasburicase. Ngokufanayo, i-doxorubicin, uhlobo lwe-chemotherapy olusetyenziswa ekuphatheni iintlobo ezininzi zomhlaza, lunokubangela ukuchithwa kweeseli ebomvu kubantu abaneentlobo ezithile ze-G6PD.

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Aspirin

I-Aspirin, esetyenziswa ngokuqhelekileyo ukunyanga iintlungu okanye ukuvuvukala, kufuneka igwenywe. Abanye abantu bathabatha i-aspirin imihla ngemihla njengenxalenye yonyango yabo yonyango. Xa ugwema i-aspirin, kubalulekile ukuba ukhumbule ukuba kufumaneka kwiinkcukacha ezininzi ezinjenge-Anacin, iBuffin, i-Ecotrin, i-Excedrin, i-Powders kunye ne-Goody's Powders. Itholakala kwakhona kwi-Pepto-Bismol. Ngokubanzi kwezinye iimeko zokunciphisa iintlungu ezinjenge-acetaminophen okanye i-ibuprofen zinyamezela ngaphandle kwemiba.

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Mballballs

Ewe, abantu basebenzisa i-mothballs. I-Mothballs ingaqukatha ikhemikhali eyaziwa ngokuthi yi-naphthalene engayenza i-hemolysis kubantu abane-G6PD. I-Naphthalene inokufumaneka kwiifayigantshi, ingakumbi ezo zisetyenziselwa ukugcina iinyoka. U-Nafthalene ngumphunga owenziwe yii mveliso ukwenzela ukuba ukunyanzeliswa kungabakho ukusondeza umphunga okanye ukuwagcoba.

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IHenna

Kukho iingxelo zecala ezipapashwe ngokubonisa i-henna (ezisetyenziselwa i-tattoos zesikhashana okanye idayi yeezinwele) ziye zaphazamisa iintlungu ze-hemolytic kubantu abane-G6PD. Iintsana ezineminyaka engaphantsi kweenyanga ezi-2 zibonakala zingenakukwazi ukuphendula ngale ndlela.

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Ubhontshisi beFava

Ukulahleka kwe-G6PD kuthiwa yi-favism; ngakumbi iintlobo ezinzima kakhulu ze-G6PD. Oku kungenxa yokuba ukungeniswa kweembotyi ze-fava (ezikwaziwa njengeembotyi ebanzi) zingabangela ukuhlaselwa kwe-hemolytic kwizigulane ezine-G6PD. Abanye bacacisa ukuba zonke izityalo (ezinjengee-peas, lentils, okanye i-peanuts) ziyakukhutshwa, kodwa ukuba ingaba oko akuyiyo imfuneko ayiyaziwayo.

ILizwi

Ukuba unesifo se-G6PD, akuthethi ukuba awukwazi ukuthatha imithi. Kufuneka uqaphele ngamachiza aqhelekileyo ukuphepha. Lona alukho uluhlu olupheleleyo lwezinto abantu abane-G6PD abanokukuphepha. Kukho ezinye iimpawu eziza kubangela ukutyunjwa kweeseli ebomvu xa kuthathwa kwiqondo eliphezulu. Abanye kuphela babangela iingxaki kwiintlobo ezithile ze-G6PD. Qinisekisa ukuba uxoxela onke amayeza akho amatsha kunye nogqirha wakho ukuqinisekisa ukuba abachaswanga ngabantu abane-G6PD.

> Umthombo:
> I-Luzaatto L kunye nePoggi V. I-Glucose-6-Phosphate Dehydrogenase. Ku: Orkin SH, Fisher DE, Ginsburg D, Khangela i-AT, Lux SE kunye no-Nathan DG (Eds). I-Hematology kunye ne-Oncology ye-Infancy and Childhood (8th ed). Philadelphia: Elsevier.