U-Huntington uhlukile njani kwi-Alzheimer's?
Isifo sikaHuntington (HD) sisifo esiqhubekayo segazi elidluliselwa kwi-genetically from parents to children. Kwi-HD, amangqamuzana omchopho womntu aqala ukuhlambalaza, kubangela iingxaki zomzimba, ingqondo kunye neengxaki. Izimpawu ze-Classic ziquka ukugula komzimba , ukunyakaza okungalawulwayo kunye nokungahambi kakuhle kokuziphatha.
Izibalo zeSifo seHuntington
Abantu abangama-250,000 e-United States banayo okanye baya kuphuhlisa i-HD.
Iimpawu zivame ukuqala phakathi kweminyaka engama-30 no-50, nangona iinjongo ze- HD ezijoliswe ngabantwana abancinci njenge-2. Ziye zabonwa kubantu abaneminyaka eyi-80 ubudala, kodwa loo nto inqabile. Ngokuqhelekileyo, omncinci umntu xa iqala impawu, isantya eso siqhubela phambili. Amadoda kunye nabasetyhini banako ukulinganisa imeko.
Izibonakaliso zezifo zikaHuntington
- I-HD ye-Early Stage: Iimpawu zokuqala ze-HD zibandakanya ubunzima bokufunda izinto ezintsha okanye ukwenza izigqibo, iingxaki zokuqhuba, ukuphazamiseka, ukuguquka kwemizwelo, ukunyakaza okungenakuzikhethela okanye ukuchithwa, ukulungelelanisa kunye neengxaki zeememori zesikhashana .
- I-Middle Stage HD: Njengoko iHD iqhubela phambili kwisigaba esiphakathi, umntu unenkathazo ngokugwinya, ukuthetha, ukuhamba, ukukhumbula kunye nokugxila kwimisebenzi. Ukunyakaza kwama-writhing (okubizwa ngokuba yi- chorea ) ye-HD kunokugqithiswa kakhulu kwaye kuphazamise kakhulu ngokusebenza kwansuku zonke. Umntu unokuthi ahlakulele iimpawu ezithandekayo.
- Ixesha elide leHD: Iimpawu zeHD ezinokugqibela ziquka ukungakwazi ukuhamba okanye ukuthetha, kwaye zifuna unonophelo olupheleleyo kumncedisi. Abantu abaye bafika kwixesha elide le-HD basengozini enkulu yokukhwaza.
Yintoni Edala Izifo ZamaHuntington?
Phantse zonke iimeko ze-HD zifa, oku kuthetha ukuba isifo sizuze kubazali.
Ukuba uyihlo okanye unina unempilo ye-HD, unama-50% amathuba okuba ne-HD geni. Ukuba uzuze ifa le-HD, uza kudala u-HD. Ukuba awuzange uzuze ifa le-HD geni, awuyi kuvelisa i-HD kwaye awuyi kudlula i-gene yakho kubantwana bakho.
Phantse i-1% ukuya ku-3% yabantu abane-HD abanalo umzali ene-HD. Kwimeko apho, isifo asikwazi ukulandelwa komnye umntu kwintsapho.
Iingcali zenzululwazi zichaza i-HD gene ngo-1993. Abanye abantu abasengozini ye-HD bavavanywa igazi labo ukuze baqinisekise ukuba ngaba ngabaphathi be-gene, kanti abanye bayeka ukuvavanya kuba akukho nonyango yokunyanga kwesi sifo ngeli xesha.
Unyango lweZifo zikaHuntington
Akukho nonyango kwisifo sikaHuntington, kodwa iimpawu zokunyanzelisa ngokungenakho ukunyanga zingaphathwa nge-tetrabenazine, kuphela ukusetyenziswa kwezidakamizwa (ngo-2008) yi-US Food and Drug Administration kule mqathango. Amanye amayeza afana nalawo asetshenziswe kwi-Alzheimers angasetyenziselwa ukuphatha i-HD yokuqonda, iimpawu zokuziphatha nezomvakalelo. Ukongezelela, iziyobisi ezifana ne-haloperidol (Haldol) kunye ne-olanzapine (iZyprexa) zisetyenziswa rhoqo.
Ukusebenzisa- ngokusebenzisa iindlela ezisesikweni ezifana nokwelashwa ngokomzimba kunye nokusebenza, kunye nezindlela ezingaqhelekanga ezifana nokuhamba kunye nokuhlala esebenzayo-kwakhona kubonakala kuncedo ekunciphiseni ukuncipha kwe-HD.
Ukuthintela izifo zikaHuntington
Kukho akukho ndlela yokukhusela i-HD. Nangona kunjalo, ukugcina umzimba osebenzayo kunye nengqondo ephilileyo mhlawumbi kunceda ukuncedisa iimpawu okanye ukunciphisa ukuqhubela phambili.
Ukugxekwa kwezifo zikaHuntington
Ukugxekwa kwe-HD kuyimpofu ngeli xesha. Umyinge wokuhlala kwexesha lokuphila emva kokuxilongwa kuphakathi kweminyaka eyi-10 ukuya kwe-20. Ukufa ngokuqhelekileyo kubangelwa kwiinkathazo ze-HD, ezifana nokukhahlela okanye ukungakwazi ukulwa nosulelo njengemiphunga ye-pneumonia. Nangona kunjalo, ekubeni i-gene echaphazelekayo yokudlula i-HD iye yachongwa, abaphandi bajolise kwesi sifo ngokufunda iziphumo kwintliziyo, ngenjongo yokuguqula umonakalo.
Kukho izilingo eziqhubekayo zeklinikhi ukuvavanya amayeza kunye nezinye iindlela zokonyango.
Izifo zikaHuntington zihluke njani kwi- Alzheimer's's Disease ?
Iimpawu ze- HD kunye ne-Alzheimer ekuqaleni ziyafana, nangona i-HD yobudala beminyaka yokuqala (iminyaka engama-30 ukuya kwe-50) incinci kunesifo se-Alzheimer, apho amaninzi amatyala akhula kubantu abaneminyaka engama-65. izakhono zokwenza izigqibo kunye nokukwazi ukufunda izinto ezintsha.
Njengenkqubela ye-HD, abantu babonisa ukunyakaza kwama-classic writhing; E-Alzheimer's, ukukwazi ukuhamba komntu ngokuqhelekileyo kunzima kunzima, kodwa abaqhelekanga ukunyakaza okungazibandakanyi. Ekupheleni kwexesha le-HD, abantu banokukwazi ukuqonda oko abanye bathetha kubo, kwaye iintsapho kunye nabahlobo banokuhlala baziqhelana nabo. Ekupheleni kwexesha le-Alzheimer's , abaninzi abantu abakwazi ukuqonda abanye kwaye ababonakali baqonda abanye ababajikelezile.
Ukongezelela, phantse zonke iimeko ze-HD zizuzwe ngelifa, ngelixa iimeko ezininzi ze-Alzheimer azizukufa ngokuthe ngqo.
ILizwi
Kuqhelekile ukuba unenkxalabo eninzi xa wena okanye othandekayo wakho ufunyanwe ukuba unayo, okanye uvavanywe kakuhle, isifo sikaHuntington, Ukwazi ukuba kukho ezininzi izixhobo kunye nezixhaso ezifumanekayo zinokuba luncedo njengoko ufunda oko unokuzilindela kunye nendlela yokujamelana nayo. Unokufuna ukuqala ngokuqhagamshelana ne-Huntington's Disease Society of America, njengenye yemibutho emininzi enokunika ulwazi oluninzi kwaye ingaba ngamaqela enkxaso yendawo.
Imithombo:
Society of Alzheimers. Iingxaki ezibangeleyo zeDementia.
I-Huntington's Disease Society of America. Izigaba zeZifo zikaHuntington.
I-Huntington's Disease Society of America. Ziziphi izifo zeHuntington.
Isiko seSizwe seNational Psychology and Stroke. Isizwe seZiko lezeMpilo. I-NINDS yeSifo seNgcaciso yeMfo.