Ukusetyenziswa kwexesha elide leeNSAID ezikhuselekileyo?
Ukuba unentlungu engapheliyo, unamathuba ukuphendukela kwii- NSAID ngenjongo yokuphucula intlungu ubuncinane kanye ngexesha elithile. Kodwa ngaba i-NSAID isebenzise ixesha elide? Ziziphi iziphumo ezichaphazelekayo? Nantsi into omele uyenayo malunga ne-NSAID yeentlungu ezingapheliyo.
Ziziphi i-NSAID?
Izidakamizwa ezichasayo ezingenakuvuthayo, okanye ii-NSAID, iintlobo zonyango eziye zisoloko zisetyenziselwa ukunyanga iintlungu zesisundu kunye kunye kunye, nangona zingasetyenziselwa intlungu yesibindi kwezinye iimeko.
Ii-NSAID ziwela phantsi kweentloko zee -analgesics ezingekho ii-opioid okanye iimvavanyo zentlungu engenazo i-narcotic. Ngokuqhelekileyo, ukusebenzisa ii-NSAID zentlungu engapheliyo kuyasebenza kakhulu xa intlungu yakho ibumnene okanye iyingqinisiso.
Ngokungafani ne- opioids , ezininzi ze-NSAID zingathengwa kwi-counter. Ibuprofen kunye ne-naproxen, zombini ii-NSAID, zifumaneka ngokukhawuleza kwiindawo zokuthengisa iziyobisi. I-NSAID ezinamandla zokunyanga-mboleko ziyafumaneka kwakhona ukuba intlungu yakho inzima kakhulu. Kule meko, ii-NSAID zinokudibana kunye ne-opioids ukulawula kakuhle intlungu yakho.
Indlela i-NSAID iXhobisa ngayo ubuhlungu
Ii-NSAID zinciphisa intlungu ngeendlela ezimbini. Okokuqala, ziguqula iintlungu zithintela ii-enzyme ezithile ezithatha inxaxheba kwimpendulo yentlungu. Okwesibini, basebenze ukunciphisa ukuvuvukala okudla ukudibana neentlobo ezithile zentlungu. Ezinye i-NSAID, nangona kunjalo, ziyasebenza kuphela ekunciphiseni ukuvuvukala xa zithathwa kwizinga eliphezulu.
Uninzi lwe-NSAID zithathwa ngomlomo, kwaye amandla anokwahluka ngohlobo lwamayeza kunye nemilinganiselo esetyenziswayo.
Xa uthatha ii-NSAID zintlungu engapheliyo, ungathatha inqaku elifutshane elisebenzayo lidibanisa kunye neyeza zentlungu ezinde, ezifana ne-opioid okanye i- analgesic adjuvant (i- anticonvulsant okanye i-anti-depressant). Oku kuyinyani ngokukodwa ukuba unentlungu . Nangona kunjalo, i-NSAID enomsebenzi omdala weentlungu ezingapheliyo inokwanela ukulawula iimpawu zakho.
Iintlobo ze-NSAID zoPhando olungapheliyo
Eminye ye-NSAID ye-NSAID yokufumana intlungu engapheliyo iquka i- aspirin , ibuprofen, i- naproxen ne-ketoprofen. Ezi zinyango zintlungu zithengiswa ngamandla amaninzi angagunyazisiyo kwaye zingadityaniswa nezinye izithako, ezifana ne-caffeine okanye i-acetaminophen.
Iinguqulelo zamandla ezinobumba ze-NSAID ziyafumaneka kwakhona. Ezinye izinto eziqhelekileyo ezisetyenziswayo ii-NSAID zentlungu engapheliyo ziquka i-meloxicam kunye ne-celecoxib. Phantse zonke i-NSAID, zombini umyalelo kunye nangaphezu kwe-counter, ithathwa ngomlomo.
Ngaba i-NSAID ikhuselekile kwi-Pain Chronic?
Xa ii-NSAID zisetyenziselwa rhoqo kwixesha elide, njengokuba kunjalo ngokubandezeleka okungapheliyo, amandla okuba nemiphumo yecala iyanda. Ubungqina bubonisa ukuba iingxaki ezinxulumene ne-NSAID ziyakhula xa ukhula. Ezinye iziphumo eziqhelekileyo ziquka:
- Isithukuthezi esiswini kunye nezilonda
- Isisu (GI) ukuphuma
- Ukwandiswa kwamandla okukhuba
- Ukugqithisa kwempawu zesifo se-asthma
- Umngcipheko wokwanda kwesifo, isifo senhliziyo kunye negazi
Ukuba uceba ukuba kwi-NSAID yexesha elide lobuhlungu, ugqirha wakho unokuguqula umyinge. Unokukubonelela ngamanye amayeza enomdaka owenza ukuba unakho ukuphuhlisa naziphi na iimeko ezi ngasentla.
Unokwenyuka kweengxaki ze-NSAID zonyuswa ukuba:
- Umsi
- Phuza utywala rhoqo
- Ngaba aphezulu
- Yiba nembali yesifo senhliziyo
- Unomfutho wegazi ophezulu
- Ngaba wakha naziphi na iingxaki ze-GI
- Unesifo okanye isifo sesibindi
Zonke i-NSAID, zombini umyalelo kunye nangaphezulu kwee-counter, ngoku izibhengezo zesexwayiso zemidlalo ngenxa yesigqibo soLawulo lwezoKutya kunye noLawulo lweeMithi. Nangona izilumkiso, ukusebenzisa ii-NSAID kuhlala enye yezindlela ezithandwa kakhulu ekunciphiseni ubuhlungu.
Imithombo:
I-American Chronic Pain Association. I-APCA Amachiza kunye nobuhlungu obungapheliyo: I-Supplement 2007.
I-American College yeGastroenterology. Iingozi Ze-Aspirin ne-NSAID.
I-Merck Manuals iTree Library yeLayibrari. Ubuhlungu: unyango.
I-US Food and Drug Administration. I-COX-2 ekhethiweyo (iquka i-Bextra, i-Celebrex, kunye ne-Vioxx) kunye ne-Non-Steroidal Anti-Inflammatory drugs (I-NSAIDs).