Amagqirha ngamanye amaxesha Nika iAnticonvulsants for Management Pain
Ukuba unentlungu ethile yentsholongwane engapheliyo , unokumangaliswa xa ufumanisa ukuba imithi yokulwa nexinzelelo ingakunceda ukukhulula intlungu yakho.
I-Anticonvulsants, okanye imithi yokulwa ne-anti-seizure, isebenza njengama- analgesics adjuvant . Oko kuthetha ukuba banokuphatha ezinye iintlobo zentlungu engapheliyo nangona ayilungiselelwe loo njongo.
Nangona ukusetyenziswa okuphambili kweyeza zokulwa nokuxhatshazwa kukuthintela ukuthinteka, i-anticonvulsants ibonakala iyasebenza ekuphatheni iintlobo ezithile zeentlungu ezingapheliyo.
Ezi ziquka intlungu ye-neuropathic , efana ne-peripheral neuropathy, kunye neentloko ezingapheliyo ezifana ne-migraines.
Ngaba Amachiza Olwachasayo Awanceda Uncedo Oluqhelekileyo?
Izifundo zenziwa kwi-anti-seizure medication for pain.
Ezinye izifundo ziphakanyisiwe ukuba ezinye iintlobo zongenelelo lwamachiza kufuneka zenziwe uphando phambi kokuba unyango olusisigxina lunqunywe unyango olungapheliyo , ngelixa abanye bathi i-anticonvulsants yindlela yokuqala yonyango kwaye ithambekele ekubeni negalelo elide elide elide.
Amachiza ambalwa okulwa neengxaki zokuxhatshazwa yi-FDA avunyelwe ukuba unyango olungapheliyo, kuquka ne-carbamazepine (ye- trigeminal neuralgia ) kunye ne-gabapentin (ngenxa ye- neuralgia , okanye i-shingles intlungu).
Ukusetyenziswa kwamachiza okulwa ne-anti-seizure ezinye iintlobo zentlungu engapheliyo kubhekwe "ukusetyenziswa kwelebula," njengoko kuye kwaba nezifundo ezimbalwa ukuphanda ukusebenza kwazo kwixesha elide lokulawula ubuhlungu obungapheliyo.
Iimpawu eziqhelekileyo zokusetyenziswa kweMithi yokuLawulwa kweMpilo
Nazi ezinye zeyeza zokulwa neentambo eziqhelekileyo ezisetyenziselwa ulawulo lweentlungu:
IGabapentin (Neurontin) . I-Gabapentin ivunyiwe ukuba yonyango lwe-postherpic neuralgia. Kusebenza kwakhona ekuphatheni i-neuropathy ye-diabetes.
Carbamazepine (Tegretol) .
I-Carbamazepine yayisisiseko sonyango olusisigxina sokuxhatshazwa kwegazi, ngokukodwa kunyango lwe-neuralgia ye-trigeminal (apho i-FDA ivunyiwe). Kwakhona kusebenza kakuhle kwintlungu yesifo sikashukela kunye ne-posturalp neuralgia.
Pregabalin (eLyrica) . I-Pregabalin yintsholongwane emitsha yokulwa neentambo ezisetyenziselwa ubuhlungu obungapheliyo, intlungu ehambelana ne-postherpic neuralgia kunye neuropathy ye-neuropathy.
Tiagabine (Gabitril) . I-Tiagabine yinkqubo yokuxhatshazwa kwezilwanyana ezisetyenziselwa intlungu ye-neuropathic ehambelana nokulimala kwentsholongwane, njengentlungu yesandla .
I-Topiramate (Topomax) . I-Topiramate yipilisi yokulwa nexhatshazo esetyenziswa rhoqo njengonyango lwe-prophylactic migraine. Iprophylactics ithathwa ukuthintela intlungu kunokuyilawula xa iqala.
Valproic Acid (Depakote) . I-Valproic acid iyimichiza yokulwa nefuthe esetyenziselwa intlungu ye-migraine kwaye inokusebenza ekuphatheni ezinye iintlobo zentlungu yesifo.
Lamotrigene (Lamictal) . I-Lamotrigene ingasetyenziselwa ukunyanga iintlungu ezinxulumene ne-neuralgia kunye neentlungu eziphakathi kweentlungu, okanye intlungu enxulumene ne-stroke.
Ezinye iiMilisi zokuShatshazwa kunye noPhando olungapheliyo
Ngenxa yendlela abasebenza ngayo kwinkqubo ye-nervous, la mayeza anxamnye ne-seizure mayeza anokuba luncedo ekwenzeni unyango olungapheliyo.
Ukuphumelela kwabo ekulawuleni ubuhlungu obungapheliyo, nangona kunjalo, akuzange ifundwe ngokupheleleyo:
- Phenytoin
- Phenobarbitol
- Clonazepam
- Oxcarbazepine
- Zonisamide
- Levetiracetam
Iimpembelelo ezingasemva
Amachiza okulwa noxinzelelo anemiphumo embalwa yecala xa kuthelekiswa nezinye izixhobo zonyango zangexesha elide.
Iziphumo eziphambili ziquka:
- kulala
- ukungcola
- ukukhathala
Amachiza okulwa neentambo zingabangela iziphumo ezilandelayo:
- ukuqothulwa
- isicaphulelo
- ukudideka okanye ingxaki ekugxilwe kuyo
- ukulahlekelwa kwemali okanye ingxaki ngokulungelelanisa
- mbono ombini
- intetho edibeneyo
- utywala
- ukulahleka kwesidlo
- umlomo owomileyo
Khumbula: Amayeza achaphazela bonke abantu ngokuhlukileyo. Amava akho aya kuba ahlukile. Ukuba unenkxalabo malunga nokuthatha imishanguzo yokulwa neentlungu zokugula, khuluma nomboneleli wakho wezempilo ngokukhawuleza.
Imithombo:
I-American Chronic Pain Association. I-APCA Amachiza kunye nobuhlungu obungapheliyo: I-Supplement 2007 .
I-Tremont-Lukats, IW, Megeff, C., no-Backonja, MM Anticonvulsants for Syndromes Neuropathic Pain Syndromes: Iinkqubo zokuSebenza kunye nokuBakho kwiNyango. Zi yobisi. Ngo-2000 Nov; 60 (5): 1029-52.
Wiffen, PJ, Collins, S., McQuay, HJ, et al. Izidakamizwa zeAnticonbulsant for Pain Acute and Chronic. I-Cochrane Database yoVavanyo oluQinisekile 2005, iNcwadana yesi-2.