Ingxaki efana neParkinson kodwa ngeeNtsingiselo ezibalulekileyo
Xa umdlali waseBrithani kunye nomculi uDudley Moore wafa ngo-Matshi 27, 2002, isizathu esisemthethweni sokufa sasibhalwe njenge-pneumonia. Kodwa, inyaniso, uMorey wayekade elwa nesimo esinqabileyo esaziwa ngokuqhubekayo kwepranyucalytic palsy (PSP) ebangela ukugqithiswa ngokuthe ngcembe kweengxenye zeengqondo ezilawula ukulinganisela, ukulawulwa kwemisipha, umsebenzi wokuqonda, kunye nokunyanzelisa ngokuzithandela nokungazibandakanyeki njengokugwinya kunye neliso ntshukumo.
Iimbangela zoPhulo lweSunyukliya eziPhambili
Nangona i-cause of infranuclear infarrys epidyrgy is ininzi engaziwayo, kucinga ukuba inxulumene nokuguqulwa kwincenye ethile yemfuza ebizwa ngokuba yi-chromosome 17.
Ngelishwa, akukho konke okuqhelekileyo ukuguquka. Nangona phantse wonke umntu onomdla we-PSP unokukhubazeka ngokofuzo, ngokunjalo, ngaba zibini kwisithathu kubemi bonke. Ngaloo ndlela, ukuguqulwa kokubonakala kubonakala kunokuba yinto eyodwa yeso sifo. Iimfucu zendalo kunye neminye imiba yemfuza nayo inokudlala indima.
Iingcali zenzululwazi ayinakunyaniseka ngokupheleleyo ukuba i-PSP inxulumene nesifo sika-Parkinson okanye se-Alzheimer apho ikwabelana ngempawu ezithile.
I-PSP iqikelelwa ukuba ifuthe omnye wabantu abayi-100,000 kungakhathaliseki ukuba uhlanga, i-geography, okanye umsebenzi. Amadoda athambekele ekutshintsheni kancane kunabesifazane. Iimpawu zivela phakathi kweminyaka engama-50 no-60.
Iimpawu zePSP
Esinye seziganeko ezibalaseleyo, "iimpawu" zePSP ziquka ukulawulwa kwamehlo, ikakhulukazi ukujonga phantsi. Le meko, eyaziwa ngokuba yi-ophthalmoparesis, ibangela ukuba buthathaka okanye ukukhubazeka kwezihlunu ezithile ezisebusweni. Ukunyakaza okubonakalayo kwamehlo kuya kuthinteka kakhulu.
Njengoko imeko ibuhlungu, ukukhangela phezulu kunokuchaphazeleka.
Ngenxa yokungabikho kolawulo oluphambili, abantu abafumana i-ophthalmoparesis baya kuhlala bekhalaza ngemibono emibini, umbono obonakalayo, kunye novelwano olukhanyayo. Ulawulo olungapheliyo lwekhosidi lungenzeka.
Njengoko ezinye iinjongo zeengqondo zichaphazelekayo, i-PSP iya kubonakalisa ngeentlobo zeempawu eziqhelekileyo ezithatha ixesha elibi kakhulu. Ezi ziquka:
- Ukungaqiniseki kunye nokulahleka kwemali
- Ngokuqhelekileyo ukunciphisa ukunyakaza
- Ukuthutha kwamagama
- Unzima ukugwinya (dysphagia)
- Ukulahleka kwememori
- Imisipha yomzimba
- Ukujiva phambili kwekhanda ngenxa yokuqina kwentamo yentamo
- Ukungabikho kwamanzi e-Urinary
- Utshintsho ekuziphatheni, kuquka ukulahlekelwa kwe-inhibition kunye nokuqhuma ngokukhawuleza
- Ukuphungulwa kwengcamango engacacanga kunye nengqiqo
- Ukulahlekelwa kwezakhono zombutho okanye ukucwangcisa (ezifana nokulawula imali, ukulahleka, ukugcina izibophelelo zomsebenzi)
Ukuxilongwa kwePSP
I-PSP idla ngokungaqondakaliyo kumanyathelo okuqala kwesi sifo kwaye idlalwa ngokungafaniyo kwintsholongwane yeendlebe, ingxaki ye-thyroid, isifo okanye isifo se-Alzheimer (ikakhulukazi asebekhulile).
Ukuxilongwa kwenzelwa ngokusekelwe ngokubanzi malunga nokuhlaziywa kweempawu. Yinkqubo apho oogqirha kufuneka babeke ngaphandle kwezinye izizathu ezinokwenzeka. Ukufundwa kwe-imagination magnetic resonance (MRI) ye-brainstem ingasetyenziselwa ukuxhasa ukuxilongwa.
Kwiimeko ze-PSP, kuya kubakho iimpawu zokuchitha (inrophy) kwinxalenye yengqondo edibanisa ingqondo kumgca wesipelini. Kwi-MRI, umbono ocaleni lo buchopho buza kubonisa oko abanye bathi "ipenguin" okanye "uphawu lwe-hummingbird" (olubizwa ngokuba lulo hlobo lufana nolweentaka).
Oku, kunye neempawu, uphando oluhlukileyo, kunye nokuhlolwa kofuzo, kunokubonelela ubungqina obufunekayo ukwenzela ukuxilongwa.
Indlela iPSP eyahlula ngayo kwi-Parkinson's disease
Ukuze kuhlukaniswe i-PSP kwi-Parkinson, oogqirha baya kuthatha ingqalelo izinto ezinjenge-posture kunye nembali yengonyango.
Ngokomzekelo, abantu abane-PSP baya kubamba ukugcinwa kwesigxina okanye ukuxhaswa kwangaphambili, ngelixa abantu abane-Parkinson bafuna ukufumana isikhundla esiphezulu.
Ukongezelela, abantu abanePSP banokukwazi ukuwa ngenxa yokungahambi kakuhle kwemali. Nangona abantu abane-Parkinson nabo banomngcipheko omkhulu wokuwa, abo abanePSP bavame ukwenza njalo emva ngenxa yokuqina kobunzima beentamo kunye nokubuyisela emuva.
Xa kuthethwa oko, i-PSP ithathwa njengengxenye yeqela leengxaki ze-neurodeergenerative ezibizwa nge- Parkinson-plus syndrome apho abanye baquka i-Alzheimer's.
Izinyango Zonyango
Akukho zonyango ezithile zePSP. Ezinye izigulane ziyakwazi ukuphendula kwiziyobisi ezifanayo ezisetyenziselwa ukuphatha i-Parkinson, njenge- levodopa , nangona impendulo ihlala ihlwempuzekileyo (enye enye indlela eyahlukileyo isetyenziselwa ukuxilonga lesi sifo).
Ezinye iimithi ezichasayo, ezifana neProzac, Elavil, neTofranil, zinokunceda ezinye zeempawu zengqondo okanye zokuziphatha umntu onokuba nazo. Ngaphandle kwamachiza, iiglasi ezikhethekileyo (i-bifocals, iifenms) zinokunceda ngeengxaki ezibonakalayo, ngelixa ukuhamba kwezixhobo kunye nezinye izixhobo ezinokuguqulela zingaphucula ukuhamba nokukhusela ukuwa.
Nangona unyango lwezonyango aluyi kuphucula iinjongo zeenjini, zinokukunceda ukugcina umlenze wokudibanisa kunye nokuthintela ukubola kwemisipha ngenxa yokungasebenzi. Kwiimeko ze-dysphagia ezinzima, ityhubhu yokutya ingafuneka.
Ukuveliswa kwee-electrode kunye ne-generse pulse ezisetyenziselwa ukuphulukiswa kwengqondo ejulile ye-Parkinson ayizange ibonise ngempumelelo ekuphatheni i-PSP.
ILizwi
Nangona kungabikho kokuqonda malunga ne-PSP kunye nokukhetha okunyanzelwanga kunyango, kubalulekile ukukhumbula ukuba isifo asikho ikhosi kwaye siyakwazi ukuhluka ngokubanzi kumntu kumntu. Ngokubonelela ngonyango kunye nokutya okunomsoco, umntu onomdla we-PSP, ngokwenene, aphile iminyaka, nangamawaka eminyaka, emva kokuxilongwa.
Kubantu ngabanye kunye neentsapho eziphila nesifo, kubalulekile ukufuna inkxaso ukuze ugweme ukuzihlukanisa kunye nokufumana ulwazi olubhekiselele kwizigulane kunye nokudluliselwa kolwazi. Ezi ziquka imibutho efana ne-New York City-based CurePSP enikezela kumntu kunye namacandelo enkxaso ye-intanethi, i-directory yeengcali zonyango, kunye nenethiwekhi yabaxhasi baqeqeshiweyo.
> Umthombo:
> Ling, H. "Indlela yokwelapha kwiSpranuclear Palsy." I-Journal ye-Disvement Disorders. 2016; 9 (1): 3-13.