Uphando olusakhulayo alukaze luchaze ukusebenza kwe-Butyrate
I-butyrate i-acid e-short chain-fatty acid ehlanganiswayo emathunjini. Ngexesha lokutya, i-carbohydrates ihamba kwinkqubo yokuqumba. Enye yeemveliso zale nto ihamba. I-butyrate enemas iye yafundiswa ukusetyenziswa ekuphatheni izifo zesibindi (IbD) , kunye ne-ulcerative colitis ngokukodwa. Nangona kunjalo, ngeli xesha, akukho mvumelwano malunga nokuba, okanye nini, ukucoca i-enemas ingasetyenziselwa ukunyanga izigulane ezinezilonda zesisu okanye ezinye iindidi ze-IBD (njenge-Crohn's disease).
I-Butyrate i-Fuel yeBhunga
Ezinye i-carbohydrates zidlula emathunjini ngaphandle kokuba zityhuke ngokupheleleyo kwaye zityiwe. Esikhundleni saloo nto, zixutywe yi-bhakteria kwikholoni (intloko enkulu), kwaye umphumo kukudalwa kwemveliso eyahlukeneyo. I-butyrate yenye yezinto ezizaliswayo, kodwa ayinakunyulwa ngumzimba. I-butyrate iyasetyenziswa njengophethiloli ngamaseli kwindawo yecolon.
Kutheni i-Butyrate ingaba neNcedo ekuPhatheni i-Ulcerative Colitis
I-butyrate iboniswe ukuba inenzuzo kwiiseli kumathumbu emathunjini ngokulwa nokuvuvukala, ukuthintela iiseli ukuba zibe ngumhlaza, ukunciphisa imiphumo yoxinzelelo lwe- oxidative , kunye nokomeleza ukukhusela kwamakholoni. I-butyrate enemas iye yaboniswa ukunciphisa uxinzelelo lwe-oxidative kubantu abadala abasemgangathweni, xa kuthelekiswa nalabo bafumana i-placebo enema ye-saline. Uxinzelelo lwe-oxidative yinkqubo eyenziwa ngamaseli kwaye angakwazi ukusebenza ngokufanelekileyo.
I-butyrate enemas iye yafundiswa ukusetyenziswa ekuphatheni i-ulcerative colitis. Ezinye iziphumo zibonise ukuba ukusetyenziswa kwezinto ezisemgangathweni zokuqhawula (oko kukuthi, ukuyisebenzisa ngqo kwi-rectum okanye ekupheleni kwekoloni nge-enema) kunokunceda ukunciphisa ukuvuvukala kwikholoni ebangelwa yi-ulcerative colitis. I-butyrate enemas inokusebenza kakhulu ekuphatheni i-ulcerative colitis kwiindawo zokugqibela zekholoni (ebizwa ngokuba yi- distal ulcerative colitis ).
Ixesha elizayo lokuxhatshazwa ngokuPhatha i-IBD
Nangona ezi zifundo zokuqala zibonise isithembiso esithile, i-butyrate ayisetyenziswanga ngokubanzi ukunyanga i-ulcerative colitis. Uninzi lwezifundo eziye zenziwa kwiimicebo, kodwa kungekhona kubantu. Ubuncinane isifundo esisodwa sisetyenziswe ngomlomo ngaphandle kwe-enema, kodwa kwakhona isifundo sasisegundwini, kwaye izifundo zabantu azikaze zenzeke. Ababhali beeninzi zezifundo ngokucwangcisa kubonisa ukuba uphando olongezelelweyo lufunekayo. I-Butyrate iye yafundiswa ekusebenziseni kwisifo sikaCrohn, nangona okwangoku asikho uphando oluninzi njengoko kukho ukukhwabanisa kunye ne-ulcerative colitis. Kodwa kuye kwaxelwa ukuba ezinye iinkonzo zonyango zonyango ziyekezela ukuba izigulane zabo zinezilonda zesilonda kwi-colon.
ILizwi
I-butyrate iyatholakala kwi-counter-counter, ngoko kubalulekile ukuxelela igastroenterologist kunye namanye amagqirha xa uthatha le ncedisi, nokuba yifom yefilda okanye njenge-enema okanye i-suppository. Akukho zingaphi iingxelo zempembelelo embi kakhulu, kodwa kubalulekile ukuba kuqinisekiswe ukuba akukho miphumo emibi okanye ingozi ekusebenziseni oku, okanye ezinye, izongezelelo, ukuphatha i-IBD. Kubantu abanesifo esibi esadlulela ngaphaya kokuphela kwekholoni, i-enema okanye i-suppository inokuthi ingabi nempembelelo eninzi, ngoko ke ithembela kuyo njengokuba unyango lunokubangela ingozi xa isetyenziswe kwenye indawo yonyango elisebenzayo.
Ukunyangwa kwe-IBD kunokubandakanya ezininzi iindlela zokwelapha kunye nokufumana into esebenzayo ibalulekile, ugcine engqondweni ukuba akukho unyango oluye lwabonisa isithembiso kwisifundo sophando luya kusebenza ngoluhlu olubanzi lwabantu abanesifo.
Imithombo:
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