Izitatimende zichazwe kwiimeko apho ukutya kunye nokuzivocavoca akwanele ukunciphisa amazinga e- cholesterol yakho. Ngenxa yokuba banako ukuphazamisa yonke imiba yepropid profile yakho, i-statins enye yeyona migaqo echanekileyo echanekileyo yokunciphisa iipilisi. Nangona unokuba ucinge ngezinga eliphezulu le-cholesterol kunye ne-triglyceride amanqanaba njengento ekukhathazeka ngayo njengoko ukhula, unokuba ne-high cholesterol inqanaba elincinci, ngokunjalo-nakwii-20s, 30s kunye ne-40s, ngokuqhelekileyo malunga nexesha abaninzi abafazi baqala ukuba nabantwana.
Ukuba neqondo eliphezulu le-cholesterol lithetha ukuba unokufakwa kwiyeza zokunciphisa i-cholesterol njenge-statin.
Kukho iinqununu ezisixhenxe kwiimakethe zase-US:
- Crestor (rosuvastatin)
- Lescol (i-fluvastatin)
- Lipitor (atorvastatin)
- L ivalo (pitavastatin)
- Mevacor (lovastatin)
- Pravachol (pravastatin)
- Zocor (simvastatin)
Yonke i-statins ithwala uhlobo lokukhulelwa lwe-X, oko kuthetha ukuba izilwanyana kunye / okanye izifundo zabantu zibonise umngcipheko wokuvelisa iimpazamo zokuzalwa xa uthatha isiza. Ngako oko, amayeza akulo mkhakha akufanele athathwe xa ukhulelwe okanye uceba ukukhulelwa ngaphandle kokuba iinzuzo zokuthatha iyeza zingaphaya kwingozi engayinceda umntwana. Akukho zifundo ezininzi ezihlolisayo imiphumo yemimiselo yabasetyhini abakhulelweyo, kodwa izifundo ezikhoyo zibonisa ukuba kukho ubuncinane ukuba ukuthatha i-statins ngexesha lokukhulelwa kunokuchaphazela ukuphuhliswa kwengane yakho.
Ukukhulelwa kunye neeNkcazo: Uphando
Izifundo zezilwanyana azizange zifikelele. Iirubhi kunye neerati ezinikezwe ezinye iimimiselo zibonise ukungaqhelekanga kokuphuhliswayo, ezifana ne-vertebrae edibeneyo, izibambo ezifudumeleyo kunye nobukhulu besincinci. Nangona kunjalo, akuzona zonke izilwanyana ezithintekayo kwezi ziphoso. Uphando lwabantu alukwazanga ukugqitywa.
Nangona iiphene zokuzalwa, ezinjengeentsilelo zentliziyo, i-palate palate, iziphene ze-neural tube, kunye nezinye izinto ezingaqhelekanga zenzeke, zazingathi zinqabile. Ukongezelela, uninzi lwabafazi kulezi zifundo lunezinye iimeko ezikhoyo ngaphambili (ezifana nesifo sikashukela okanye ukukhuluphala komzimba) okanye besithatha isigqirha esingaphezulu kwesinye okanye isigqirha esingaphezu kwe-counter-counter, esingaba negalelo kwiziphene ezichazwe kule zifundo. Ngokomnye umenzi wesigxina, iziganeko zokuphuhlisa ezi mpazamo zazinge-4%.
Ngoko, ukuba uthatha i-statin kwaye uceba ukukhulelwa, kufuneka uvumele umboneleli wakho wezempilo ukuba azi izicwangciso zakho. Umboneleli wakho wezempilo unokukutshintshela kwelinye unyango kuba ubuhlobo phakathi kokuthatha izitembu kunye nokuphuhliswa kweziphene zokuzalwa kumntwana wakho akunakucinywa. Ukongeza, ukuba sele ufumene ukuba ukhulelwe, kufuneka uxelele umboneleli wakho wezempilo ngokukhawuleza. Uya kugqiba isigqibo sokuba ngaba uncedo lwe-statin lube lukhulu ngaphezu kweengxaki ezibangelwa umntwana wakho.
Imithombo:
Bateman BT, Hernandez-Diaz S, Fischer MA, et al. Izitatimende kunye neentsholongwane zomntwana: isifundo seqela. Br Med J 2015; 350: h1035.
UThixofrey LM, uErramouspe J, uCleveland KW. Umngcipheko we-statogenic of statins ekukhulelweni.
UAn Ann Umama wama- 2012; 46: 1419-24
I-Ofori B, u-Rey E, uBerard A. Umngcipheko wokungabikho komntwana ongaphantsi komntwana kubasebenzisi abakhulelweyo beziyobisi ze-statin. Br J Clin Pharmacol 2007; 64: 496-509.
Petersen EE, Mitchell AA, Carey JC et al. Ukunyuka komama kwiimimiselo kunye nomngcipheko wokukhubazeka kokuzalwa: ityala leenkcazo. Am J Med Genet 2008; 146A: 2701-2705.