Isifo seLyme sibangelwa isifo kwi-british Borrelia burgdorferi . Abantu bangahlakulela isifo emva kokuba bethwa ngumthi osulelekileyo. Ngokutsho kwamaziko okuLawula nokuLawula (CDC), isifo seLyme asikwazi ukudluliselwa ngesondo, okanye ngokubamba okanye ukusela ngaphandle kweglasi njengomntu onesifo seLyme. Akukho ziganeko zokudluliselwa kumntu kumntu okanye kwisilwanyana kumntu; lidluliselwa kuphela ngamakethi.
Iikiti
Ungeke ucinge ukuba usemngciphekweni wesifo seLyme ngenxa yokuba uhlala phi. Nangona amaninzi amatyala avela kwiindawo ezithile, isi sifo sithinta zonke iindawo zaseMerika. Yaye khumbula: Nangona umngcipheko wokulinywa kwekhakiti ungancinci xa ufaka umva wakho, ngokuqinisekileyo unokunyuka xa uhamba okanye wenza izinto zokuzonwabisa.
Izinto zokuPhila kweengozi
Kukho iindlela ezithile zokuphila ezijongene nobungozi obuchaphazelekayo nokukhawulelana neengqungquthela kwaye, ngoko ke, ukukwazi ukufumana isifo seLyme. Ezi ziquka:
- Ukuba ngumzingeli
- Ukuba nezilwanyana
- Ukuhlala kwindawo yasemaphandleni
- Ukuhlala ngaphakathi, ukusebenzela, okanye ukuhamba kwelinye lamacandelo e-ticks e-United States (e-Northeast, Mid-Atlantic, okanye North-Central)
- Ukuchitha ixesha kwiindawo ezikhuni okanye ezinengca
- Ukuba nomsebenzi ongaphandle
Genetics
Nangona isifo seLyme singenalo izakhi zofuzo, unokufumana ilifa lezityalo ezenza kube lula ukuba ufumane iimpawu ezinzima xa ufumana isifo seLyme.
Ubuninzi bokubambisana kwemfuzo yesifo seLyme kucatshangelwa ukuba kukho kwiindawo ezahlukeneyo zeklasi ye-II enkulu ye-hertocompatibility complex (MHC). I-MHC ifumaneka kwingalo emfutshane ye-chromosome 6. Iquka iigesi ze-I, ii-II kunye ne-III ze-HH zegesi, ngasinye sichaphazela isistim somzimba. Izakhi zegesi ze-II zidlala indima ekwenzeni izimpendulo zee-cell ze-antigen.
Kukho uhlobo oluthile lwe-HLA ye-gene (i-genotypes) -HLA-DR4 kunye ne-HLA-DR2-edibaniswe nokubandakanyeka kwi-Lyme arthritis. Kuye kwachazwa ukuba emva kokuba i-microorganism evela kwintsholongwane yaseLyme ihambelana namajoyina, impendulo ye-immune ngokumelene nayo iyayiphendula kunye nezicubu ezidibeneyo kunye nabantu abane-HLA-DR4 kunye ne-HLA-DR2, ekhokelela ekuphenduleni ngokuzenzekelayo nokudala ngaphezulu isifo se-arthritis.
Abantu abanesifo seLyme ngokugqithiseleyo kwaye abangazange baphendule kakuhle unyango lwe-antibiotics bafumana rhoqo ukuba ne-DRC1 * 0101 ne-0401 ye-classic genotypes, ebonisa ukuphendula ngokuzenzekelayo. Uphando olusenziwayo lwenziwe kwikhonkco phakathi kwezesini kunye nesifo seLyme.
Isifo se-Lyme Disease Syndrome
Emva kwonyango, inani elincinci labantu liya kuvelisa iimpawu eziqhubekayo, oku kuthiwa abanye bathi "isifo esingapheliyo" seLyme . Kuxilongo. Ngelixa i-CDC ivuma ukuba iimpawu ezithile ziyakwazi ukuqhubeka emva kokuba unyango lugqityiwe (njengentlungu edibeneyo kunye neuropathy), ezo mpawu ziza kusombulula ihlabathi kwiinyanga ezintandathu okanye ngaphantsi. Ngaphaya kwelo xesha, kukho ubungqina obuncinane bokuthi iimpawu eziqhubekayo-ikakhulukazi ukukhathala okungapheliyo-zixhomekeke ngqo kwiintsholongwane eziqhubekayo kunye neBroralia burgdorferi .
Kuba bantu, i-CDC ibeke isifo njengesifo se-Lyme disease (PTLDS). I-CDC ilumkisa ngokuchasene nokunyanga kwamayeza e-antibiotics kunyango lwe-PTLDS.
> Imithombo:
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> Brewer JH, iTrasher JD, Straus DC, Madison RA, Hooper D. Ukufumana i-Mycotoxins kwizigulane ezineSyndy Syndrome. Iidyobisi . 2013; 5 (4): 605-617. i-doi: 10.3390 / iibhox5040605.
> Kalish RA, Leong JM, Steere AC. Umbutho Wonyango-Ukumelana Ne-Lyme Arthritis Ne-HLA-DR4 kunye no-Antibody Reactivity kwi-OspA kunye ne-OspB yaseBroralia Burgdorferi. Usulelo kunye noGawulayo . 1993; 61 (7): 2774-2779.
> Strle K, Shin JJ, Glickstein LJ, Steere AC. I-Receptor efana neToll 1 I-polymorphism idibaniswe no-T-helper Responses Respiratory Response kunye ne-Antibiotics-Refractory Lyme Arthritis. Arthritis neRheumatism . 2012; 64 (5): 1497-1507. i-doi: 10.1002 / ubugcisa.34383.
> I-World Health Organization (WHO). Mycotoxins . Upapashwe ngo-Oktobha 2011.