Indawo eyaziwa njenge-subarachnoid, indawo ye-intrathecal yindawo egcwala amanzi ephakathi kwendawo yokucwangcisa engaphakathi (kunye ne-mater) yentambo yomgogodla kunye nomgca ophakathi (i-arachnoid mater).
Ukufakelwa kweeNkqubo zoThutho lweeNtrathecal (IDDSs)
Indawo ye-intrathecal inokusebenza njengendlela yokulawulwa kweziyobisi ezisetyenziselwa ukunyangwa kolawulo lwentlungu.
Ngokomzekelo, iimpompo zezilwanyana ezisetyenzisiweyo , ezibizwa ngokuba yimpompo yentlungu okanye ipomphine, isebenzisa le ndlela.
Ukuhambisa amayeza entlungu kwisithuba se-intrathecal endaweni yokuthatha iipilisi ngeemfuno zokuthi umzimba ugqibe kwaye uphumelele amayeza. Oku kuvame ukuguqulela ekulawuleni ubuhlungu obungcono kunamanani amancinci. Ngenxa yalesi sizathu, ukujova kwimizi yesifo kwi-intrathecal indawo kunokubonelela ngokukhululeka kwentlungu xa kuthelekiswa nezinye iindlela zokwelapha kubantu abaneentlungu ezinzima, ezingenabuhlungu. Kwakhona isisombululo esingenasigxina sokujongana nosizi olungapheliyo. Ngamanye amagama, ukuba uzama kwaye ungayithandi, okanye ukuba unqumle ngendlela eyahlukileyo yonyango, akudingeki uqhubeke-upompo ungasuswa ngokukhawuleza.
Ukuveliswa kwezixhobo zonyango lwe-intrathecal kunokucetyiswa kuwe ngudokotela wakho weentlungu ukuba unesibeleko sesikhathi eside, ubuhlungu obukhulu kwaye uye wazama ezininzi iintlobo zonyango (oko kukuthi, unyango olungenayo inkunkuma okanye olungagqirha) olungenakho ukuphucula kwiimpawu zakho.
Ngokutsho kukaGhafoor, uEpshteyn, uCarson, iThahaar, uCharry noPhelps kwinqaku labo, "I-intrathecal drug for the long-term management management", eyapapashwa kwincwadi kaDisemba 2007 ye- American Journal of Health Pharmacy , kukho ukungabi ubungqina bokuxhasa ukusetyenziswa kwezidakamizwa ze-intrathecal ngokusekelwe kwiimvavanyo zeeklinikhi ezingapheliyo.
(Izilingo ezilawulwayo ezingaqhelekanga ezingaqhelekanga zihlobo oluphezulu lophando lwezophando olulinganisa unyango kunye nolunye unyango, alukho unyango okanye unyango olunyango.)
Ghafoor, kunye. Kwakhona kuthi ngenxa yokuba ezininzi iintlobo zonyango ezisetyenziswa kwiipompo ze-intrathecal zezidakamizwa azifumaneki kwimarike, kufuneka zihlanganiswe ngamayeza. Iindidi zonyango ziquka: i- opioids , i-anesthetics yendawo, i-clonidine, i-baclofen, ne-ziconotide, bathi.
Abaphandi bancedisa ukuba abaphandi bamachiza kubaluleke kakhulu kwimigangatho yokuqinisekisa imveliso ye-intrathecal ukusebenzisa i-intrathecal ngenxa yokuba bathatha inxaxheba kwinkqubo eninzi - ukusuka kwiinkcenkceshe kunye neengxaki zokuphepha ukukhusela izigulane kwizigulane ezisengozini, ukuya kumaxwebhu, ukubeka esweni nokuyalela, nokuqulunqa iziyobisi.
Iingozi zePompu zamachiza
Nangona ipompo ehambisa amayeza kwi-intrathecal isikhala sinceda abantu abaninzi banciphise intlungu yabo baze baphinde baphinde baphile ubomi babo, le nkqubo inokungena emingciphekweni embalwa. I-Medtronic, umenzi weepompo zamachiza uluhlu lwesifo sokusuleleka, ukuvuza kwamanzi emgogodla, kunye neentloko njengamathathu aphezulu. Ukungasebenzi kakubi kweso sixhobo, kunokuthi.
> Umthombo:
> Ghafoor VL, Epshteyn M, Carlson G., Terhaar D., Charry O., uPhelps P. Ulwaphulo lweMithi ye-Intrathecal ye-Arrangeal for Pain Management Pain Management. IJ Health Syst Pharm. Disemba 2007.
> IiNzuzo kunye neengozi - Iipompo zamachiza. Ubuhlungu obungapheliyo. Medtronic.