Ngaphandle kokuba ukhangele ukuphucula emva kwentlungu okanye emva kwentlungu, ugqirha wakho uya kuphakamisa ukuba athathe iyeza zentlungu ehamba phambili. Kodwa kukho iintlobo eziliqela, kwaye iqhinga liyazi ukuba yiyiphi into eyokukhetha, kwaye kutheni.
Okokuqala makhe sixoxe ngento ethethwa ngayo ngokuthi "iindidi" zepilisi zentlungu engaphezu kwe-counter. Ezi zizahlula "isithako esisebenzayo," into eyenza utshintsho, umzekelo, ukunciphisa intlungu, ukunciphisa ukuvuvukala, njl., Ezichazwe kwiibhile zephayibhile. (Izithako ezisebenzayo zingenza iziphumo zempembelelo, ngokunjalo, le nto inokudlala indima kwisigqibo sakho sokuthatha elinye iyeza kunomnye.)
Njengoko uza kubona, izithako ezisebenzayo zingahlanganiswa ndawonye kwiiklasi zonyango. Ngokubhekiselele kwizidakamizwa zentlungu engaphezu kwee-counter, iiklasi ezimbini eziphambili zi-NSAID (ezingezizo-steroidal anti-inflammories) kunye nama-analgesics (ubuhlungu bukhululekayo). ngamanye amaxesha akayi kuba.
Yonke enye yeziyobisi ezichazwe apha yi-NSAID ezingaphezulu kwe-counter, ezinganciphisa intlungu, ukukhulelwa komkhuhlane. I-COX-2 inhibitors, olunye uhlobo lwe-NSAID, lunokukunceda ekuphatheni iimpawu zakho, kodwa ezi ziyobisi zifumaneka ngonyango kuphela.
Uninzi lweziyobisi ziluhlu olude lweziphumo, kwaye ii-NSAID azifani. Ezinye iziphumo zecala le-NSAID zingaba yingozi kwimpilo yakho; ezimbini zeengozi ezinkulu zokuthatha olu hlobo lwezilwanyana zihlaselwa yintliziyo kunye nezilonda zesisu. Kwakhona, zombini bobubi kakhulu.
Kwaye ekugqibeleni, iziyobisi ezixutywa apha ngezantsi zifumaneka njengemithi emiselweyo kwizinga eliphezulu.
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AspirinI-Aspirin mhlawumbi imithi endala yokutshaya eyaziwa ngabantu. I-acetylsalicylic acid, isithako esisebenzayo kwi-aspirin, isetyenziswe njengentlungu yokubuyisela iinyanga, ukuba kungengamashumi eminyaka (ngeendlela ezahlukeneyo.)
Njenge-NSAID, i-aspirin ayigcini nje ekunciphiseni ubuhlungu okanye imva, idlala indima ekulawuleni ukuvuvukala, okunokuba luncedo emva kokulimala okanye ukuxhatshazwa.
Isithako esisebenzayo kwi-aspirin senza umsebenzi wayo ngokubamba umkhiqizo we-prostaglandines, eziyimichiza emfutshane emzimbeni, enoxanduva lokuvuvukala , kunye nentlungu.
Nangona inqabileyo, i-aspirin ingaba nemiphumo emibi kakhulu, kungekhona ubuncinane ubunzima beengxaki zesisu. Kodwa ngokungafani nezinye i-NSAID, i-aspirin, xa isetyenziswa ngokuchanekileyo, inakho ukuphucula impilo yengqondo. Thetha nogqirha wakho malunga nale nto ungathanda ukwazi ngakumbi.
Ngenxa yoko, iingcali ezininzi zikholelwa ukuba kuzo zonke i-NSAID, i-aspirin iyona nto ikhethekileyo. I-Pharmacy yaBantu, eyona yewebsite eneenkcukacha kunye nevediyo yomsakazo oboniswe kwiRadio kawonkewonke kaRhulumente yenza le nkcazo:
"Ukuba sasixoshwe kwisiqithi senkangala kwaye sasingathatha nje intlungu enye, siya kukhetha i-aspirin."
Izizathu, zithi, kukuthi kunye nokunciphisa intlungu kunye nokunciphisa ukuvutha, i-aspirin inceda ukunciphisa umngcipheko weemeko zengqondo ezinjenge-heart attach or stroke. Kwaye, i-Pharmacy yaBantu ithi, ubungqina bubonisa ukuba i-aspirin inokunika inzuzo yokuchasa umdlavuza, ngokunjalo.
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IbuprofenIbuprofen isilwanyana esichasayo abantu abathile bathatha ukunciphisa ubuhlungu obukhulu, ukunyamezela, ukuvuvukala nokuqina ngenxa ye-arthritis. Ibuprofen nayo isetyenziselwa ukunciphisa ama-muscle aches kunye nentlungu yokuzola ngenxa yenkxalabo yangemva.
Amagama ebhanti aquka uMotrin, Advil noNuprin.
Njenge-aspirin, ibuprofen yi-NSAID, oku kuthetha ukuba akunciphisi nje ukunciphisa intlungu emva okanye intamo kodwa idlala indima ekuqukethe inkqubo (ukuvuvukala) ngokwayo. Izidakamizwa ezichasayo kunye ne-ibuprofen njengesithako esisebenzayo zivimbela ukuveliswa kwe-prostaglandin, ngoko ke ukuvuvukala nentlungu.
Imiphumo emibi ingabandakanya iingxaki zesisu kunye neziganeko zomoya.
Ngo-2015, i-FDA, ngokusekelwe kuphando oluhlaziyiweyo, luqinisekisile iimfuno zamagama kubakhiqizi kwiiphakethe ze-ibuprofen kunye nee-Labels Drug Facts. Oku kwakukwazisa uluntu malunga nemingcipheko ethile ehambelana nalo mxube osebenzayo.
Esinye sezilumkiso ezibalulekileyo kule ngcaciso esitsha kukuba umngcipheko wesifo okanye ukuhlaselwa kwentliziyo kubakho kwangaphambili kwinkqubo yokonyango ngaphezu kweengcali ezazikholelwa ekuqaleni.
"Akukho xesha lokusetyenziswa elingabonakali ngaphandle kwengozi," kusho uJudy Racoosin, MD, MPH, usekela-mlawuli weCandelo le-FDA ye-Anesthesia, i-Analgesia, kunye ne-Products Addiction.
Ukuzikhusela ekugqithiseni okungafunekiyo (kwaye ngenxa yoko ingozi eyingozi kakhulu okanye eyingozi) I-FDA icebisa ukujonga izithako ezisebenzayo kwiileyibrari zeDrug zamayeza ngamnye ozithathayo, kwaye qi niseka ukuba enye yodwa iqulethe i-NSAID. Ngamanye amagama, ungathathi ngaphezu kwe-NSAID enye ngexesha.
Esinye isilumkiso kukuba abo sele benesifo senhliziyo, okanye abaye baphelelwa yintliziyo yonyango basengozini enkulu yeso siganeko senhliziyo kunye nokuthatha ibuprofen okanye enye i-NSAID.
Ukuba unesifo senhliziyo, umngcipheko womnye (kwaye mhlawumbi ufa nayo) uphezulu, kwakhona.
Kodwa wonke umntu, kungakhathaliseki ukuba yintoni imeko yabo yempilo ye-cardiovascular ibeka engozini enkulu yokuthatha ibuprofen, i-FDA iyasixelela.
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NaproxenI-naproxen , enye i-NSAID, isetyenziselwa ukunciphisa intlungu ngenxa yokuxhatshazwa kwemisipha kunye ne-arthritis. Oku kubandakanya i-osteoarthritis kunye ne-inflammatory arthritis efana ne-spondylitis e-ankylosing. A
Nje ngezinye izidakamizwa ezichasayo, i-naproxen isebenze kakhulu ngokuvimbela ukubunjwa kwama-prostaglandin.
Amagama ebhanti aquka iAleve neNaprosyn.
Qaphela ukuba ngelixa zonke i-NSAID (kunye noluphi uhlobo lwe-aspirin) luphakamisa umngcipheko wokuhlaselwa kwintliziyo okanye ukubetha, ubuncinci olunye uphando lubonisa ukuba i-naproxen iphakamisa into encinci.
Oku kungenzeka kukuba i-naproxen isilwanyana esisebenza ixesha elide, apho ibuprofen isebenzayo. Isilwanyana esisebenzayo eside asidingeki sithathwe rhoqo, ngaloo ndlela sikubonisa ingozi encinane kwimiphumo yecala leziyobisi.
Okokuthi, i-website enegunya, i-Drugs.com, ithi imiphumo echaphazelekayo ye-GI yokuthatha ii-NSAID (oko kukuthi izilonda zesisu kunye / okanye ukuphuma kwegazi) kwandisa ixesha elide uthabatha olu hlobo lwesilwanyana. Basixwayisa uluntu ukuba kuthathe kuphela umthamo ophantsi kunyanzelekile ukuhambisa intlungu.
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ITylenol (i-acetaminophen)I-Tylenol yiyona nto isetyenziselwa ukubuyisela ubuhlungu emakethe. Iyakuthatyathwa ukuphumula kwexesha elifutshane xa unesihlungu esilula okanye esilinganiselweyo emva okanye entanyeni yentlungu. Akusiyo i-NSAID.
I-Tylenol inceda intlungu ye-back back and / or arthritis . Inokusebenza ngokunciphisa inani lemichiza yengqondo ekhangisa izibonakaliso zentlungu, ngaloo ndlela, echaphazela inkqubo ye-nervous central . Kwakhona kunomphumo wokupholisa ngokuvimbela ii- prostaglandines ezidlala indima kwinqanaba lokulawula ubushushu.
Kodwa ukuba unengxaki yesibindi, okanye ukuba udla utywala obuninzi, kufuneka uhambe ngokucophelela xa ufika eTylenol. Kulula kakhulu ukuthatha izidakamizwa ezininzi, ezinokubangela ukuba utywala obunzima okanye obunobungozi bubulawe.
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Ngaba Imithi Yobunzima Impela Kuwe?Ababhali be-2017 isifundo esashicilelwe kwiphepha leNgxelo ye- Medicine ukuba ngelixa iindlebe ezininzi zentamo kunye nezikhalazo ezilethwa oogqirha zihamba kunye nje nexesha lokuhamba, zihlala zibuyela (kwakhona.)
Olu buhlungu kunye nolwalamano lwabaxhamli luyomelele ngakumbi, bathi, phakathi kwezinto zokuqala kunye nezilandelayo. Ngokukodwa, isiqendu sokuqala siphelile, ubuhlungu beentlungu ezisezantsi buya kubuya kamva. Kwaye kwakuba lixesha ngalinye liyakwenza, kuya kuba nzima kakhulu, kwaye mhlawumbi kubangela ukukhubazeka okungaphezulu.
Ngale ndlela, ujikelezo lwakho lokuqala lwentlungu ebuyisela emva, lunokuthi lube lubi ngakumbi, kwaye lunokufaka isandla kwixesha elide lokubuyela emva, ukuqala.
Ababhali bachaza ukuba ubuhlungu bentlambo ngenye yeemeko ezinokukhubaza ezintlanu e-US
Ngenxa yoko konke oku, unokuba ufuna ukuqiniseka ukuba ukuthatha imishanguzo yakho yintlungu okanye intamo yakho yonke inene, ngokuqinisekileyo, ikhondo lakho elifanelekileyo.
Olunye ufundo lwe-2017, olu papashwe kwi- Annal of Rheumatic Diseases , xa kuthelekiswa ukuthatha ii-NSAID ukuze zithinte iintlungu zentlungu ngokungenzi nto.
Ngoxa ii-NSAID zanceda ngeentlungu, kwakungenjalo. Enyanisweni, abalobi baphetha ngokuthi akukho nto ilula ye-analgeics esebenza kakuhle (xa kuthelekiswa ne placebo.)
Yaye xa ubeka umngcipheko wegazi le-GI kunye ne / okanye izilonda, kunye / okanye umngcipheko ophezulu wokuhlaselwa kwintliziyo okanye uhlangothi, unokufuna ukucinga kwakhona isicwangciso sakho sokunceda intlungu - ingakumbi ukuba intlungu yakho ibuhlungu.
Esinye isicwangciso esithandwa kakhulu ongayenza sisenzo.
Ucwaningo olwenziwa ngo-2014 olupapashwe kwi- Ochsner Journal lufumene ukuqinisa imisipha engaphantsi kunye / okanye intamo ecimazelayo (ekhoyo emva kwaye ikuncedise u-arch kunokuba uguqule okanye ujikeleze umlanjeni wakho) kunceda ukunciphisa intlungu kwaye kunokukunceda uhambe ngokukhawuleza uninzi lweentlobo iingxaki zomgudu. Xa uhamba ugqirha malunga nentamo yakho okanye intlungu yangemuva, cinga ukuthatha indlela eqhubekayo ngokumcela ukuba atyunwe kwiyeza.
> Imithombo:
> Dreisinger, T., PhD. Ukuzivocavoca kwi-Management of Chronic Back Pain Ochsner J. Spring 2014. https://www.ncbi.nlm.nih.gov/pmc/article/PMC3963038/
> I-FDA Yomeleza isilumkiso se-Heart Attack kunye ne-Stroke Risk ye-Non-Steroidal Anti-Inflammatory Drugs. Iwebhusayithi ye-FDA. Ukuhlaziywa: Sept 2016. https://www.fda.gov/ForConsumers/ConsumerUpdates/ucm453610.htm
> Graedon, J. Aspirin kunye neeNSAID: Yiyiphi eyona nto ibhetele? Pharmacy yabantu. Julayi 2013. https://www.peoplespharmacy.com/2013/07/08/aspirin-vs-nsaids-which-is-best/
> Machado G., et. al. Izidakamizwa ezingezange-steroidal ezichasayo izilonda zomzimba: ukuphononongwa ngokuchanekileyo kunye nokuhlaziywa kwemeta. Ann Rheum Dis. Julayi 2017. https://www.ncbi.nlm.nih.gov/pubmed/28153830
> Naproxen vs Ibuprofen: Yintoni eyahlukileyo? Website yeDrugs.com. Agasti 2016. https://www.drugs.com/answers/naproxen-ibuprofen-difference-3117722.html
> Sinnott P., et. al. Imiba yokuxilongwa kwentamo ebuhlungu kunye neemeko zangemuva, ngo-2002 ukuya ku-2011. Iyeza (iBaltimore). NgoMeyi 2017. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5440123/