Ukutshala ixesha elithathayo ukufunda izinto ezisisiseko zokuthatha i-Aleve okanye i-naproxen kunokukunceda ukuba ugweme imiphumo emibi kunye neengxaki.
I-Aleve ( isithako esisebenzayo se- naproxen) yinyango engeyona-steroidal anti-inflammatory (NSAID) esetyenziselwa ukukhululeka kwentlungu, ukunciphisa umkhuhlane kunye nokunciphisa ukuvuvukala. Ngenxa yesenzo sayo sokulwa nokuvuvukala, i-naproxen -kuba ichongiwe okanye ithengwe phezu kwe-counter- mayayinceda njengenxalenye yonyango lwenkcitho okanye intlungu ehambelana nomgudu we-arthritis; Oku kubandakanya i- spondylitis engavumelaniyo (uhlobo lwe-arthritis evuthayo) kunye ne-osteoarthritis.
I-Naproxen ingathengwa ngaphezu kwe-counter kwi-esitolo sakho sezilwanyana njenge-brand Aleve, okanye njenge-generic. Kodwa ngokusekelwe kwiimpawu ozibonisayo, ugqirha wakho unokugqiba ukuba idosa ephezulu inokuthi ilandelwe. Kwimeko apho, unokukunika umyalelo.
Ungayithatha Kangakanani I-Naproxen?
Ukuba uthatha i-naproxen ye-counter-counter for pain, izikhokelo zokupakisha ziya kuncoma enye ipilisi nganye kwiiyure ezisibhozo ukuya kwii-12 ngelixa unempawu. Ileta iya kukuxelela ukuba kulungile ukuthabatha iipilisi ezimbini ngeyure yokuqala, kodwa kungengqiqo ukuthabatha ngaphezu kwembini kwiiyure eziyi-8 ukuya kweyure eziyi-12, okanye ezintathu kwiyure ezingama-24.
I-Drugs.com incomela ukuthatha u-440 mg ngomlomo ngeyure yokuqala njengoko kufuneka, kwaye u-220 mg ngomlomo emva kweeyure ezisibhozo ukuya kwi-12, kwakhona, njengoko kufuneka. Bathi kwakhona i-dosage esiphezulu ayifanele ibe ngaphezu kwe-440 mg kwixesha leyure elinesibhozo ukuya kwe-12 okanye i-660 kwiyure ezingama-24.
Izinto zitshintsha ukuba ugqirha wakho ubeka i-naproxen entanyeni okanye entlungu. Ngaloo ndlela, i-Drugs.com ithi i-dose ye-naproxen yokuqala ephakanyisiweyo ingaba phakathi kwe-500 no-1000 mg, kuxhomekeka ukuba ngaba ithebhulethi inokukhutshwa ngokukhawuleza okanye uhlobo lokukhululeka olulawulwayo. Bathi kwakhona iipilisi zokulibala ezilibaziseko azikhuthazwa ukuba zibuhlungu.
Emva kweso salelo sokuqala (kodwa kusekunjalo ngosuku lokuqala) isincomo sithathe i-275 mg yesilwanyana sokukhululwa ngokukhawuleza ngomlomo nganye kwiiyure ezithandathu ukuya kweyibhozo, okanye ngama-550 ngomlomo nganye kwiiyure eziyi-12 njengoko kuyimfuneko yokutshatyalaliswa kwempawu. Kodwa gcinani engqondweni ukuba umthamo omkhulu wokukhutshwa kwipilisi ekhutshwa ngokukhawuleza ethathwa ngomhla wokuqala ngowama-1375 mg. Ngeentsuku ezilandelayo, ngu-1100 mg.
Kwiipilisi ezilawulwayo ngosuku lokuqala (emva kwe dose yokuqala), unokwandisa ukuya kwi-1500mg. Kodwa kwiintsuku ezilandelayo, isincomo ukuzisa umthamo ukuya kwi-1000mg okanye ngaphantsi.
Qaphela ukuba enye i-Aleve iqukethe i-200mg naproxen kunye ne-20mg sodium.
I-Naproxen Isisombululo Sengcaciso malunga neArthritis Related Related Spine Conditions
I-osteo kunye / okanye i- arthritis evuthayo, amanani ase-naproxen anconywayo aphantsi.
Xa kuziwa kwiiphilisi zokukhululwa kwangoko, i-Drugs.com ithi ithathe phakathi kwe-250 ne-500mg ngomlomo kabini ngosuku. Emva koko, ukuqala ngosuku lwesibini, unokwandisa umthamo ukuya kwi-1500mg ngomlomo. Kukho isilumkiso kwezinye izigulane-eli xabiso lemilinganiselo linga khuseleka kuphela kwiinyanga ezintandathu.
Ngaba uthatha (okanye ucinga ukuthatha) i-naproxen ye-spondylitis engavumelekanga? Ukuba kunjalo, umlinganiselo ophakanyisiweyo we-750mg ukuya ku-1000mg ngomlomo kanye ngosuku, okanye 375 ukuya ku-500mg ngomlomo kabini ngosuku.
Kwaye i-osteoarthritis, isincomo esiphakathi kwe-750mg ukuya ku-1000mg ngomlomo kanye ngosuku.
Ulibale ukuthabatha i-Naproxen
Ukuba ulahlekelwa umthamo, thabatha enye ngokukhawuleza. Ixesha eliza kubakho xa liphantse ixesha elizayo. Kwimeko apho, lindela kude kube lixesha lokuyithatha kwakhona. Hlalani nisondele kwishedyuli yexesha eliqhelekileyo kwaye ningalokothi niphindwe kabini la mayeza.
Ukugcina iNaproxen
Khusela ngokukhuselekileyo i-naproxen yakho ngokuyigcina ivalwe ngokuqinileyo kwisitya, kwaye kude nokushisa kunye nokunyuka. Oku kuthetha ukuyigcina kwindawo yokuhlambela. Kwakhona, i-naproxen ifanele igcinwe kwiqondo lokushisa. Yilahle xa iphelelwe yisikhathi, okanye awuyikuyidinga kwakhona.
Unokuzibuza ukuba wakho umkhemikhali indlela engcono yokwenza oko. Gcina naproxen ngaphandle kokufikelela kwabantwana.
Mechanism Action Action
Wonke amayeza eklasini ye-NSAID, kuquka ne-naproxen, umsebenzi ngokubanzi ngokuvimbela ukubunjwa kweekhemikhali kumzimba obizwa ngokuba yi- prostaglandins . Le ndlela iyona ndlela iphambili isiza esiluncedo. (Ukuba unomdla, i-prostaglandin yinto ejongene nayo, phakathi kwezinye izinto, ukuvelisa ukuvutha kunye nentlungu ephumela kuyo.)
I-Naproxen Ukukhusela
Uninzi lwabantu-kuquka abaqeqeshi bempilo abaninzi abanelayisenisi-bangaphantsi kwengcamango yokuba ukuthatha i-naproxen ngokubanzi kukhuselekile.
Ingaba uyazi okanye awukho, nangona kunjalo, isithako esisebenzayo kwi naproxen asifanelekanga wonke umntu. I-Naproxen iye yadibana ne-GI tract, ne-kidney, kunye neengxaki ze-cardiovascular. (Siza kuthetha ngokubanzi malunga nelo ngezantsi.)
Ngenxa yokuba iziphumo ezichaphazelekayo ezinxulumene nale ntlungu zintlungu zihlala zibi kakhulu kwimvelo, kulungile ukuthatha kuphela imali efunekayo, ngexesha elifutshane elifanelekileyo.
Ugqirha wakho ngumntu ongcono kakhulu kukukunceda ukuba unqume ukuba kuthatha ixesha elingakanani kunye nokuba kaninzi kangakanani (njengakuphi na iziyobisi). Ukuba akafumaneki ukuba athethe nawe, landela imiyalelo kwipakethe ngokucokisekileyo, kunye / okanye ubuze i-pharmist yakho. Kodwa musa ukuthatha ngaphezulu okanye ngaphantsi kwexabiso elinconywayo, kwaye unamathele kwixesha eliphakanyisiweyo.
Iingxaki eziMbi kakhulu
Njengokuba ubuhlungu obukhulu kakhulu buhlungu kunye ne-anti-inflammatory, i-naproxen ingaba yingozi enkulu kwimpilo yakho.
Okokuqala, kunokwenzeka ukuba uphendule. Oku kungabonakala njengemingcebo, ukuvuvukala ubuso, isifuba, ukukhwabanisa kwesikhumba, i-blister, okanye ukutshitshiswa. Ukuba kukho enye yezi zibonakaliso zenzeka, yeka ukuthatha i-naproxen uze ufune ingqalelo yonyango.
Oku kulandelayo isiphumo esaziwayo nesicala kakhulu sesisu sokuphuma kwamanzi. Kubalulekile ukuhlala uqaphele-ukuba ufumana izibonakaliso okanye iimpawu zokuphuma kwegazi, khangela uncedo lwezonyango. Ukwenza oko kunokulondoloza ubomi bakho.
Okwesithathu yiprofayili yengozi ye-cardiovascular risk of taking any NSAID. Ngokutsho kukaGregory Curfman, MD, uMlawuli oyiNtloko, i-Harvard Health Publications, sibonile, ngaphezu kweminyaka eyi-12 edlulileyo, ubungqina obusakhulayo bokuthi ukuthatha i-NSAID bangela umngcipheko kwindlela yakho ye-cardiovascular system. Iingozi zempilo ebhekisela kuzo zibandakanya ukuhlaselwa kwintliziyo, ukungaphumeleli kwentliziyo kunye nesifo; umngcipheko ochaphazelekayo ophezulu wegazi.
Ngokusekelwe kuphando zophando, i-FDA, ngo-2015, yayifuna abavelisi ukuba baqinise izilumkiso zabo malunga nale mingcipheko yempilo yeCV kwiiphakheji ze-NSAID kunye ne-labeling. Ukubhaliweyo ngoku kufuneka kukuxelele ukuba umngcipheko wokuhlaselwa kwentliziyo kunye nokushaywa ngxabano kunokunyuka, nokuba ngaba usebenzisa ii-NSAID kuphela kwiiveki ezimbalwa, kwaye ukuba amayeza aphezulu athatyathwa ixesha elide angase abe yingxaki.
U-Curfman uphinda uxelele ukuba izigulane sele zifunyanwe ngesifo senhliziyo, ukuthatha i-naproxen akunakwenzeka ingcamango enhle. Oku kunokwandisa, uthi, abo bangenaso isifo senhliziyo esaziwayo.
Oko kwathiwa, ngoxa i-2016 isiDanish isifundo safumana intlangano phakathi kwexesha elifutshane le-ibuprofen okanye i-diclofenac unyango kunye nomngcipheko wokuqala wesiganeko senhliziyo, abazange bakwazi ukubona nayiphi na intlangano phakathi kwe naproxen kunye neziganeko ezinjalo. I-Aspirin isabonwa njengengozi ephantsi yeNSAID.
Iimpawu zokuba zikhangele oko zingabonisa ukuba isiganeko senhliziyo siquka ukusabalalisa okanye iimvakalelo ezinxulumene nentliziyo yakho, njengentlungu yesifuba, ubuthathaka, ukuphefumula okufutshane, intetho ekhutshweyo okanye umbono okanye ukulinganisela iingxaki. Ukugcinwa kwe-Fluid esinye isibonakaliso ofuna uncedo lwezempilo olukhawuleza.
Eminye Imiphumo engaphandle
Ukulimala kwesibindi kungenye inkxalabo yokuthatha i-naproxen okanye enye i-NSAID. Iimpawu zesibindi sesibindi zibandakanya isicupunu, ukuhlanza, ukulahlekelwa yintlanzi, ukubetheka, ukuluhlaza kwesikhumba kunye / okanye amehlo, iimpawu ezinjengomkhuhlane kunye nomchamo omnyama. Ukuba unayo yale nto, yeka ukuthatha naproxen uze ufune unyango lwangonyango.
Kwaye ekugqibeleni, kukho uluhlu lweminye imiphumo engabonakaliyo okanye engaphantsi kweleyo esiye sathetha ngasentla. (Qaphela ukuba uluhlu aluphelelanga, ngoko ke ukuba ufuna ulwazi oluthe xaxa khangela i-Drugs.com.) Thetha nogqirha wakho ngokukhawuleza ukuba unako ukuba kukho na enye yale mpawu isebenza kuwe:
- ukutyunjwa , urhudo okanye igesi
- izilonda emlonyeni
- unxaniwe kakhulu
- intloko
- i-dizzy okanye i-head headed
- elele
- iingxaki zokulala
- ukutshisa okanye ukubetha kwiingalo okanye emilenzeni
- Uziva ngathi unobanda
- ukukhala ezindlebeni okanye ezinye iingxaki zokuva.
Ngaba Unokuthatha I-Naproxen?
Kungabonakala ngoku ukuba ngokubhekiselele kwiphepha lezempilo yakho jikelele kunye nophando olutsha kwi-NSAID naproxen akuyona nto eyona nto ikhethekileyo yokuphucula intlungu.
Ewe, ukuba sele sele unayo nayiphi na imiqathango ekuthethwe ngayo ngaphambili (isifo senhliziyo, isifo, isisu, iingxaki zesisu, iingxaki zesibindi) ukuthatha i-naproxen kungeyona nto ingcono kuyo yonke into, njengoko iya kuphakamisa umngcipheko wokufa. Kodwa nantsi ezinye ezimbalwa iingqwalasela.
Ngaba ukhulelwe okanye uceba ukukhulelwa? Ukuba kunjalo, kufuneka uthethe nodokotela wakho ngaphambi kokuba uthathe naproxen. Esi sidakamizwa sinokubangela iziphene zokuzalwa xa kuthathwa kwi-trimester yokugqibela yokukhulelwa. Ingadlulisa ubisi lwebele kumntwana onesihlengikazi kwaye yenze ingozi.
Kule miqolo, ukunikezela nge-naproxen kumntwana oneminyaka engaphantsi kwe-2 akukhuthazwa, ngaphandle kokuyalelwe ngugqirha wakho.
Ngokucacileyo ukuba unembali yeengxaki zentliziyo, iimbozi zegazi, uxinzelelo lwegazi oluphezulu, isisu, iingxaki zeengtso, iingubo zegazi okanye izilonda zesisu, ukucinga kwakhona nge-naproxen mhlawumbi unomdla wakho. Kwakhona, oku kungenxa yokuba ingaphakamisa umngcipheko wakho kwisiganeko senhliziyo okanye ukufa. (Jonga apha ngezantsi ukuze ufumane ezinye iinkcukacha.) Uthabathe nayiphi na imveliso ye-naproxen ngaphambi okanye emva kokuba intliziyo iqhutywe yintsebenziswano ayicebisi.
Njengoko sathetha ngasentla, i-NSAID ifikelele umngcipheko wezilonda, igaye kwisisu esiswini kunye nezinye iingxaki zeGI. Ezi ziphumo zibi kakhulu. Gcina ukhumbule ukuba zinokuthi zenzeke nangaliphi na ixesha, kwaye zingabonakalisa ngaphandle kokulumkisa kwangaphambili. Abemi beMatriki bangaba mngcipheko ophezulu. Ngoko ukuba sele usenayo ingxaki ye-GI, sebenza kunye nodokotela wakho ukufumana isisombululo esifanelekileyo soxolo.
Kwakhona, ukusela kunye ne-naproxen akuxubeki. Ukusetyenziswa kotywala ngokubambisana ne naproxen yindlela enye yokwandisa umngcipheko weengxaki kunye neengxaki ze-GI.
Ezinye iimeko ezinokunyusa umngcipheko weempawu zengozi zengozi ye-naproxen zibandakanya i-asthma, iipolps kwimpumlo, ukuphuma kwamanzi kunye nokuphazamiseka kwe-clotting, ukubhema, isikhumba esikhathalela ukukhanya kwelanga, kwaye, njengokuba isifo sesibindi nesifo sesibindi okanye iingxaki.
Ukusebenzisana kwezidakamizwa kunye nokugqithisa
Sivele sathetha kancane malunga nokuxuba utywala kunye ne-naproxen; ayikho-hayi! Kodwa ukuba uthatha ezinye iindidi zonyango, nokuba ngaba (nokuba nazo) iziyobisi zintlungu okanye zitshatyalazi / izidakamizwa ezingapheliyo ungagqiba ngokugqithisa ngengozi. (Ezininzi i-OTC imithi iqulethe ii-NSAID, nangona oko akulona uhlobo lwesithako esisebenzayo esithengiswayo kwiintengiso, okanye kwi-shelf shelf.) Ngenxa yesi sizathu, kubaluleke kakhulu ukufunda zonke iileyile zamachiza (i-OTC kunye nemiqathango) ngaphambi kokudibanisa. Qinisekisa ukuba ufumana enye idoksi ye-NSAID kumaxesha afanelekileyo (njengoko kuchazwe ekuqaleni kweli nqaku.)
Ukuba ucinga ukuba usenokuba ngaphezulu, shayela u-911 okanye isikhungo sakho solawulo lweetyhefu.
Yikholwa okanye cha, ukuxuba ukuxhaswa kwezondlo, imifuno, iziyobisi zokuzonwabisa, kunye / okanye ikhofi inokusebenzisana ne naproxen kwaye ishintshe indlela esebenza ngayo emzimbeni wakho. Thetha nomboneleli wakho wezempilo malunga nemilinganiselo yokulinganisa nganye kunye / okanye enye intlungu yokunciphisa izinto.
Njalo uxoxe nodokotela wakho ukuba ufuna okanye kufuneka uyeke ukuthatha nawaphi na amayeza.
Kanye kunye neziyobisi kunye nezinye izinto eziye zaxutyushwa kule nqaku, ngezantsi ziluhlu lwamachiza anokunxibelelana ne naproxen ngendlela engafanelekanga. Qiniseka ukuba udibane nodokotela wakho okanye ukhemistri ukuba ezinye iilesi (okanye) ziluhlu, okanye ukuba uthatha amanye amayeza okanye iziyobisi:
- utywala
- i-alendronate, ethathelwe ukukhusela ukulahleka kwethambo
- ezinye i-NSAID, kuquka i- aspirin . Ukuba usebenzisa i-aspirin ixesha elide, amathuba akho okuphuma ngeesisu ayenyuka.
- ezinye izidakamizwa ezichasayo (ezifana ne- ibuprofen okanye i-prednisone)
- i-entecavir, ngenxa ye-hepatits-B
- i-cidofovir, ethathwa ngenxa yokusuleleka kwizilwanyana kwizigulane ze- HIV
- i-cyclosporine, enikwe ukutshintsha izigulane
- iipilisi zamanzi (i- diuretics )
- uxinzelelo lwegazi, njengeACE inhibitors
- igazi elincinci njengeCourmadin, okanye amanye amayeza aphatha okanye avimbele iifutha zegazi
- methotrexate, isichemotherapy
- pemetrexed, isichemotherapy
- iimveliso zeemveliso eziqukethe i-feverfew, igalikhi, i-ginger, okanye i- ginkgo biloba
- iyeza le-lithium njenge-Eskolith Lithobid
ILizwi
I-Naproxen inokuba luncedo kwimeko yakho, kodwa ukwenza uninzi lwayo kufuneka uyisebenzise ngokukhuselekileyo. Kungakhathaliseki ukuba ufumana i-naproxen yakho kwi-counter okanye njengemigqirha evela kugqirha wakho, qiniseka ukuba ulandele imiyalelo yokulinganisa kwaye uqaphele imiphumo emibi kunye nokusebenzisana. Ukuba uvakalelwa kukuba into ayilungile, qhagamshelana nogqirha wakho.
> Imithombo:
> Curfman, G., MD, uMlawuli oyiNtloko. I-FDA iyomeleza isilumkiso sokuba ii-NSAID zandisa ukuhlaselwa kwintliziyo kunye nobungozi be-stroke. YeHarvard yezempilo. School Harvard Medical School. Julayi 2015. http://www.health.harvard.edu/blog/fda-strengthens-arning-that-n-ids-increase-heart-attack-and-stroke-risk-201507138138
> Naproxen. Website yeDrugs.com. Ukuhlaziywa kokugqibela: Epreli 2017. https://www.drugs.com/naproxen.html
> Sondergaard KB, Weeke P, Wissenberg M, et al. Ukusetyenziswa kweziyobisi ezingekho-steroidal ezichasene nezidakamizwa zidibene nomngcipheko okhulayo wokubanjwa kwesifo esibhedlele ngaphandle kwesibhedlele: isifundo solawulo lwexesha lelizwe lonke. I-European Heart Journal - I-Cardiovascular Pharmacotherapy. Ngo-2016. https://academic.oup.com/ehjcvp/article/doi/10.1093/ehjcvp/pvw041/2739709/Non-steroidal-anti-inflammatory-drug-use-is