Iimvavanyo zegazi zisetyenziselwa ukuxilonga i-arthritis kunye nokubeka esweni umsebenzi wesifo
Kubaluleke kangakanani ukuhlolwa kwegazi ekufumaneni i-arthritis ? Ziziphi iimvavanyo zegazi eziyalelwe ngokuqhelekileyo kwaye ziphi iinkcukacha abazibonelela ngesigulane ngasinye?
Kwakhona, xa isiguli sinemiphumo emibi yokuhlolwa kwegazi ngezibonakaliso zesifo se- arthritis, kodwa zinempawu zekliniki ezinjengeentlungu, ubomvu, ukufudumala, ukuvuvukala, nokuqina kobudlelwane babo - ngaba ama-labs angalunganga avimba ukuxilongwa kwe-arthritis?
I-Rheumatologists (oogqirha abaneengcali kwi-arthritis kunye neemeko ezihambelanayo) ngokuqhelekileyo bahlela ukuhlolwa kwegazi ukuze bancede baqinisekise okanye bangabandakanyi ukuxilongwa kwekliniki. Ngokomzekelo, khawucinge isigulane esinembali engama-3 yesigxina sobungqina obusondeleyo obunxulumene nentlungu kunye nokuvuvukala kwesandla okanye isandla. Esi sigulane, ukuhlolwa kwegazi okulandelayo kunokuyalelwe ukuba kuncede ukuqinisekisa ukuxilongwa kwe- rheumatoid arthritis :
- I-Rheumatoid
- Anti-cyclic citrullinated peptide antibody
- Isantya se-sedimentation
- Iprotheyini esebenzayo yeC
Ubukho bezinto eziphathekayo ze-rheumatoid okanye i-CCP-antibody kule sigulane kuya kunceda ukuqinisekiswa kokuxilongwa kwe-rheumatoid arthritis. Ngakolunye uhlangothi, ukuya kwi-30% yezigulane ezine-arthritis ze-rheumatoid zingenayo i-antibodies, ngokukodwa kwisifo sabo. Ukongezelela, ubukho be-rheumatoid factor , ngokukodwa kwinqanaba eliphantsi, aluqhelekanga kwizigulane ezingenazo kwaye azisoze zakha i-rheumatoid arthritis.
Ulwaphulo-mthetho lwe-anti-CCP luyakwazi ukudibaniswa ne-rheumatoid arthritis, ngoko ukuba isigulane sinomgangatho ophezulu, isigulane esingenayo imbonakalo ye-rheumatoid arthritis inokuthi ikwazi ukuhlakulela isifo.
Ezinye iimvavanyo ezimbini zegazi ezikhankanywe ziyi-sedimentation rate kunye ne-CRP. Ezi zivivinyo zegazi zilinganisa ukuvuvukala kwaye zivame ukuphakanyiswa kwizigulane ezine-arthritis esebenzayo.
Amanqanaba aqhelekileyo awanakho ukulawula i-rheumatoid arthritis, kodwa ezo zigulane zingenakukwazi ukuvelisa umonakalo odibeneyo xa kuthelekiswa nezigulane ezinezinga eliphezulu lokuvuvukala. Oku kunjalo ngokwenene kwi-CRP ephakamileyo.
Uvavanyo lwe- Anti-nyukliya (ANA) lubalulekile kumzekelo wethu wesigulane ukuvavanya kwi-systemic lupus erythematosus okanye i-SLE. Nangona iinqanaba eziphantsi ze-ANA ziqhelekileyo kwi-arthritis ye-rheumatoid, amanqanaba aphezulu e-ANA kumzekelo wesigulane sibonisa ukuba kungenzeka i-lupus, ngakumbi ukuba i-anti-CCP kunye ne- rheumatoid factor are negative.
Kwizihlandlo ezilandelayo, ukuba i-rheumatoid factor okanye i-anti-CCP ifanelekile, ayisoloko iyalwe. I-sedimentation rate kunye ne-CRP, nangona kunjalo, ziyalelwa rhoqo njengoko zinokunceda ukuqinisekisa (ukongeza kwimbali yesigulana kunye novavanyo) nokuba i-arthritis isebenza okanye ixolelwe .
UScott J. Zashin, MD, uprofesa oncedisayo kwikliniki kwiYunivesithi yaseTexas Southwestern Medical School, iCandelo leRheumatology, eDallas, eTexas. UDkt. Zashin naye uhamba noogqirha kwii-Hospital zasePresbyterian zaseDallas nasePlano. Ungumntu we-American College of Physicians kunye ne-American College of Rheumatology kunye nelungu le-American Medical Association. UDkt. Zashin ngumlobi weArthritis ngaphandle kobuhlungu - Ummangaliso we-Anti-TNF Blockers kunye nombhali-mbhali we-Natural Arthritis Treatment.