Ukuqonda iingxaki ezinengxaki kunye nekhuselekileyo yokhuseleko lwegazi
Ngenxa yokuba uxinzelelo lwegazi oluphezulu kunye nezifo zesifo se- asthma zizifo eziqhelekileyo, kuyaqhelekileyo ukuba abantu babe nexesha elifanayo. Nangona le nhlanganisela ayilona yingozi kakhulu, ingabonisa imingeni enzima yokwenza unyango. Kungenxa yokuba ezinye zeemvavanyo zonyango ezichanekileyo kunye nezingqinisisiweyo zonyango ziyaziwa ukuba zenze imiphumo emibi kubantu abane-asthma, kunyanzeliswa ekuphuhliseni izicwangciso zonyango olufanelekileyo.
Iingxaki zoxinzelelo lweziyobisi
Phakathi kwezidakamizwa ezininzi ezahlukahlukeneyo ezifumanekayo ukunyanga uxinzelelo lwegazi oluphezulu, i-beta blockers kunye ne-angiotensin-yokuguqula i-enzyme (ACE) inhibitors inokubangela kakhulu iingxaki kwizigulane ze-asthmatic.
Kutheni i-Beta-Blockers Ingxaki
Iibet blockers zingabangela ingxaki ngenxa yobuninzi be-beta receptors kwiindinyana zokuphefumula. Ngoxa uvimba ukuthatha i-beta receptors kwimithambo yegazi kuyimpembelelo efunayo xa uphatha uxinzelelo lwegazi oluphezulu ngenxa yokuba kubangela ukuba imivenge yegazi ivule, ukuvimbela i-beta receptors kwiindawo zokuphefumula kubangela ukuba i-airways iyanqanda kwaye ingakhokelela kwimiphumo eyingozi.
I-blocka blockers esetyenziselwa ukunyanga uxinzelelo lwegazi alukhethi ngokukhethekileyo, ngoko ayenzi umsebenzi omhle okwahlukileyo phakathi kweentlobo ezahlukeneyo zokufumana imithwalo yegazi kunye neempumlo zokuphefumula. Oku kuhambelani ne-beta-agonist okanye ukuvuselela, iziyobisi ezisetyenziselwa ukuphatha i-asthma, njenge-albuterol, ngokuqhelekileyo ijolise kuphela kubalamkeli kwiindinyana zokuphefumula.
I-Beta-1-i-Beta Blockers ekhethiweyo
Ngenxa yokuba i-beta blockers iphumelela kakhulu ekuphatheni ukunyuswa kwengcinezelo yegazi, kwenziwe umzamo wokuphuhlisa iinguqulelo ezenza umsebenzi ongcono phakathi kweemivenge zegazi kunye neempumlo zokuphefumula. Lezi yobisi, ezibizwa ngokuba yi-beta-1--block blockers, ziye zaxhomekeka kwiinkalo ezahlukeneyo zeemvavanyo zeclini ukuze ziqinisekise ukhuseleko lwabo kwizigulane ze-asthmatic.
Uvavanyo lwezonyango kunye neziphumo zibonise ukuba ngelixa i-beta-1-blockers ikhuselekile kwizigulane ze-asthmatic, zisabonisa ukuthambekela kokunciphisa iindinyana zokuphefumula kwabanye abantu. Ngenxa yeso sizathu, ezi zilwanyana ezikhethiweyo aziqhelekanga ukuba zichazwe kubantu abane-asthma.
Kutheni i-ACE Inhibitors ingaba yingxaki
Ngokumalunga ne-beta blockers, i-ACE inhibitors ingabonisa ezinye iingxaki ukuba unesifo se-asthma. Esinye seziphumo eziqhelekileyo ezichaphazelekayo ze-ACE inhibitors ziqhubeka, ukukhwehlela owomileyo, okwenzeka kuma-20 ekhulwini labantu. Izifundo zibonise ukuba le ngqungquthela ibangelwa uhlobo lomsebenzi wokuphefumula obizwa ngokuthi "i-asthma elinganayo," oku kuthetha ukuba umsebenzi ngaphakathi kwimihlathi yokuphefumula ifana nemiphumo yesifo se-asthma. Nangona iingxaki ezinzulu kwi-ACE inhibitors ziqabile kubantu abane-asthma, ziye zabikwa. Ngenxa yezi zizathu, i-ACE inhibitors ayisoloko ithathwa njengesicatshulwa sokuqala (okokuqala) ekukhethiweyo, nangona isasetyenziswa xa nje ugqirha ugqirha ngokunyamekela iziphumo zabo.
Ukhuseleko Lwemithi Yogonyamelo
Amachiza amaninzi okwelapha umfutho wegazi okhuselekileyo aphephile ukusebenzisa kwizigulane ezine-asthma, kuquka:
I-block blockers ye-calcium nee-ARB azibonwanga ukuba zibangele nayiphi na ingozi eyongeziweyo okanye engavamile kwizigulane ze-asthmatic, kwaye ezi ziyeza zikhetho zikhetho. I-block blockers ye-calcium ithambekele ekusebenziseni okokuqala ngenxa yengxelo yabo ende kunye neendleko eziphantsi.
I-Diuretics ingenza i-Potassium ephantsi
Enye impembelelo yecandelo lezonyango-kuzo zonke izigulane, kungekhona nje abo abane-asthma-i-potassium ephantsi, ebizwa ngokuba yi-hypokalemia. Nangona zonke izigulane zinyango nge-diuretics zinomngcipheko wokuphuhlisa i-hypokalemia, lo mngcipheko uphezulu xa usebenzisa izidakamizwa ze-asthma. Iimfucu ze-asthma zinekhono lokunyanzela i-potassium ngaphandle kwegazi lakho nakwiiseli zakho, apho kungabikho ngokukhululekile.
Olu tyekelo, oludibene ne-potassium-sapping nature of diuretics, lithetha ukuba xa usebenzisa ezi zimbini iindidi zezilwanyana ngexesha elifanayo, kuya kufuneka ukuba amazinga akho e-potassium ahlolwe rhoqo. Ukongezelela, ugqirha wakho uya kukubeka kwi-dose ephantsi ye-diuretic ukunciphisa umngcipheko we-hypokalemia.
Olunye utywala lweziyobisi
Ezinye iziyobisi zentsholongwane zibhekwa zingakhuselekanga okanye zingakhuselekanga ukuba zisetyenziswe kubantu abane-asthma. Ngokuqhelekileyo, le ndawo engachazwanga kukuba izidakamizwa azifundiswanga ngokuthe ngqo kubantu abanezixinzelelo eziphezulu zegazi kunye ne-asthma. Enyanisweni, uninzi lwala machiza-kuquka i- clonidine kunye ne-hydralazine-ludla ukuba lusetshenziselwa ukuba lusetyenziswe nantoni na, oko kwenza ukuba ucinge ngokuchanekileyo ukusetyenziswa kwabo kwizigulane ze-asthma ezingathandekiyo.
> Umthombo:
> Weinberger SE, Kaplan NM. Unyango lwe-Hypertension kwi-Asthma naseCOPD. Isemgangathweno. Ukuhlaziywa ngoFebruwari 1, 2016.