Ziyiphi i-Cancers eziqhelekileyo ezinezifo zeHodgkin?
Ukuba uqala nje okanye uphakathi kwonyango le- Hodgkin lymphoma , ukuthetha ngomnye umhlaza kungokuba yinto yokugqibela ofuna ukuyiva. Ngaphambi kokuba kuxubushe ingozi kunye neerhafu zeekliniki zesibini kubalulekile ukuqaphela ukuba umngcipheko weemiphumo ezidlulileyo ezifana neekliniki zesekondari zixhomekeke kakhulu kwiintlobo zonyango. Ngaphezulu kwekota yesibini yokugqibela, izinga lokusinda iminyaka emi-5 le-Hodgkin lymphoma liye lisuka kuma-10 ekhulwini ukuya kuma-90 ekhulwini, kwaye umntu oqhelekileyo wesi sifo unokulindela ukuphiliswa.
Ukuba nolwazi malunga nokuba unomdlavuza wesibini luba luleke ngakumbi kubangenele abangenayo into eyenziwe "isinda" somdlavuza. Nangona inxalenye ebalulekileyo yokusinda kukufunda ukunyuka kwendima yakho "njengomhlaza wesigulane" kwaye uyeke ukuchazwa ngumhlaza wakho, kuya kufuneka uqikelele le mngcipheko kwaye unomdla wesikhathi eside.
Makhe sithethe ngokubaluleka kwalo mngcipheko, iirhafu zamanqwelana athile ahlobene nonyango olwenzelwe i-Hodgkin, kwaye ngokubalulekayo, jonga indlela onokuphucula ngayo impilo yakho yexesha elide emva kokuba unyango ufumane okokuqala nokunciphisa umngcipheko.
Yintoni ekuthethwa ngayo ngeCarcer Secondary?
Umhlaza wesibini emva kwesifo seHodgkin ichazwa njengophuhliso lomhlaza wesibili ongenakuhambelana nomhlaza wakho wokuqala. Isifo se-Hodgkin esibuyela emva-sibuyela kwakhona-asithathwa njengesifo somhlaza wesibini kodwa kunokuba siphinde sifumane isifo.
Umdlavuza wesibili ungathunyelwa ngamanye amaxesha njengomhlaza wesibini wesiqhelo , ugxininisa ukuba umhlaza wesibili awuhambelani nomntu wokuqala.
Unyango lwezonyango ezinjengekhemotherapy kunye neyeza zonyango ziyakwazi ukuphilisa iHodgkin lymphoma, kodwa ngelo xesha, i- carcinogens (i-cancer-causing). Umonakalo ezi zonyango kubangela ukuba i-DNA kwiiseli isebenze ngokumangalisayo ukuba inqande umzimba wakho wesifo somhlaza, kodwa ingonakalisa izinto eziyimfuza ngokuqhelekileyo, iiseli ezempilo, ngamanye amaxesha ziqalise utshintsho olungakhokelela ekuphuhliseni iseli somhlaza.
Iisondo zamachiza ezisekondari zenzeka ezinyangeni ukuya emashumi eminyaka emva komhlaza wakho wokuqala.
Iimpawu eziqhelekileyo zeCancer Cancer emva kweHodgkin Lymphoma?
Iyintoni ingozi yokuphula umdlavuza wesibili ukuba unesi sifo seHodgkin? Impendulo iya kuhluka ngokusekelwe kwonyango olulandelayo, ixesha lakho lokuxilongwa, kunye nezinye izinto ezininzi. Nangona sineengcamango ezithile ezinokuthi zenzeke kanomdla kunye nokuba kutheni kunzima ukuvavanya umngcipheko ngqo kumntu omnye. Izifundo zijonge amaqela abantu abaneHodgkin lymphoma ngokuhamba kwexesha, kodwa aba bantu baye bafumana iintlobo ezahlukeneyo zonyango ezahlukeneyo. Ekubeni omnye kumadoda amabini kunye nomnye kwabafazi abathathu kulindeleke ukuba babe nomhlaza kwimpilo yabo nangona bengenayo isifo seHodgkin, kunzima nakakhulu ukufumanisa ingozi ekhoyo.
Njengoko sithetha ngomngcipheko kunye neerhafu, gcinani engqondweni ukuba ezi zizibonelelo zisekelwe kumntu oqhelekileyo one-Hodgkin. Nangona kunjalo abantu bokwenene abanqabile.
Ngokubanzi, kucingelwa ukuba abantu abangama-20 ukuya kuma-30 ekhulwini abantu abaphila kwiHodgkin lymphoma baya kuba nomhlaza wesibili. Umngcipheko womnye wee-khansa (awunayo yonke i-cancer eyenyuka) ingama-4.6 amaxesha emngciphekweni wabantu bonke.
Ucwaningo olwenziwa ngo-2015 kwi -New England Journal of Medicine lubhekise ngaphezu kwama-3900 aseHodgkin isifo sabasindayo kwiminyaka engama-20.
Umyinge weminyaka ngexesha lokuxilongwa kwaba bantu babengama-28. Abanye balaba basindileyo babe ne-chemotherapy, abanye babenemitha, kunye neepesenti ezingama-60 bafumana ezi zimbini zonyango. Kula bantu, abantu abayi-908 bavelisa umdlavuza wesibili.
Olunye uphando lubheka abantu abane-Hodgkin lymphoma abaneminyaka engama-35 okanye ngaphezulu ngaphandle kokonyango. Umngcipheko wesifo somhlaza wesi-30 unyaka wama-33.2 weepesenti (xa kuthelekiswa nama-9.6 ekhulwini kubemi) kunye nama-48.5 ekhulwini kwiminyaka engama-40 (xa kuthelekiswa nama-19 ekhulwini).
Ziziphi iipilisi eziphakamisa ingozi yeCancer Cancer?
Njengoko kuphawuliwe ngasentla, siyazi ukuba i-chemotherapy kunye neyeza zonyango ziwonakalisa amaseli aphilileyo, kodwa ezinye iindlela zonyango zininzi kunokuba ezinye zibeke ingozi yomhlaza.
Ukunyanga kwamayeza emfubeni weHodgkin lymphoma sele kudibaniswe nomngcipheko ophezulu wesifo somhlaza webele, umhlaza wemiphunga kunye nomdlavuza we-thyroid. Kwixesha elidlulileyo, ngoko ke, amayeza emisebe kunye nobukhulu beethambo eziqhelekileyo bebukhulu kakhulu. Ngexesha elikhoyo, unyango lwe-radiation lisetyenziselwa ukunciphisa i-Hodgkin lymphoma, nangona isasetyenziswe rhoqo kwisifo sokuqala. Izaziso ezisetyenzisiweyo njengamanje zithunyelwa kwindawo echanekileyo, ephantsi kwezicubu ezichaphazelekayo yiHodgkin lymphoma (i- radiation field radiation ).
Izaphulo ezithunyelwa ngaphantsi kweengqungquthela, ngokuchasene nomlilo wesifuba, zandisa ingozi yesisu, i-pancreatic ne-colon yomhlaza.
I-Chemotherapy nayo ibangela umonakalo weselula, kodwa ezinye iiklasi zamachiza e-chemotherapy zinokubangela ukuba umonakalo onokukhokelela kwiikliniki zesibini. Uluhlu lwezilwanyana ezibizwa ngokuba yi-alkylating agents zinomngcipheko ophezulu (ngakumbi i-procarbazine). Ama-alkylating agents agxininiswa kakhulu kunomngcipheko ophezulu we- non-Hodgkin lymphoma .
I-Procarbazine ikhona kwi- BEACOPP i-chemotherapy regimen kunye ne-dacarbazine, enye i-agent e-alkylating enye yezinto ze- ABVD chemotherapy .
Ngaba Ingozi YeeKhansela ZesiSekondari Ukwandisa okanye Ukunciphisa?
Unyuselo oluninzi lwenzeke kunyango lweHodgkin lymphoma ngokuhamba kwesikhathi. Njengoko nje kuphawuliwe, ezinye zezinto ezinobungozi obukhulu kwizifo zengqungquthela zivela kwiphilisi ye-radiation kunye ne-chemotherapy kunye nama-alkylating agents.
Ngelixa kunokuba kunengqiqo yokuba umngcipheko weekliniki zesibini ziza kuhla, kuba ukusetyenziswa kwezonyango ezinxulumene kakhulu kunye neekliniki zesibini ziyancipha, abukho ubungqina bokuba oku kwenzekayo, kwaye ezinye iingcaphephe zibonisa nokuba ukwanda okwenyuka kumngcipheko.
Uninzi lweeKhansela eziqhelekileyo ezenzeke emva kweHodgkin Lymphoma Treatment
Amanqwelana aqhelekileyo asekondari kubantu abaye bafumana iHodgkin lymphoma zibandakanya:
- Umhlaza wesifuba - Umhlaza wesibeletho ngumdla wesibini wesiqhelo oqhelekileyo ofumaneka kubantu abaye baphathwa ngeHodgkin lymphoma. Kukho izikhokelo ezicetyiswayo (jonga ngezantsi) ukwenzela ukuba uhlolwe ngethuba lokuqala lomhlaza wesisu oxhomekeke kwiminyaka owaye wafumanisa ukuba unesifo seHodgkin kunye neentlobo zonyango oye wafumana. Ngokomzekelo, abafazi abafumana i-radiation yeHodgkin lymphoma (i-radiation field radiation) kwisifuba ngaphambi kokuba abaneminyaka engama-30 kufuneka babe ne-MRI kunye neeklinikhi zeemvavanyo zonyango ukususela kwiminyaka engama-30. Ngokuqhelekileyo, abafazi abaye baphathwa ngeHodgkin lymphoma kufuneka baqale rhoqo Ukuhlolwa kwesifo somhlaza kwibele kwiminyaka engama-40 kwangoko. Gcina ukhumbule ukuba amadoda angafumana umdlavuza webele.
- I-non-Hodgkin lymphoma - Njengoko kuphawuliwe ngasentla, i-non-Hodgkin lymphoma ixhomekeke kakhulu kwii-regimens ezibandakanya ama-alkylating agents njenge-procarbazine.
- Umdlavuza womlenze - Ukwelashwa kwamayeza emfubeni wesifo seHodgkin ngaphezu kwesisu ngumhlaza wesibini wesiqhelo. Abaphengululi abaninzi bakholelwa ukuba ubuchule obusandul 'ukushiswa kwamayeza buza kubangela iincinci zecala.
- Umhlaza weColon - Kunomngcipheko okhulayo womhlaza wokulala, ngokukodwa kulabo abaye bafumana i-radiation engaphantsi kwesigxina kunye ne-chemotherapy equka i-procarbazine. Uphando luqhubeka nokuzama ukufumana indlela engcono yokukhupha abantu abaye bafumana iHodgkin lymphoma abaye bafumana ezi zimbini zonyango.
- Umhlaza we-Pancreatic - Umhlaza wesiPancreti udibene kakhulu kunye ne-radiation engaphantsi kwesithintelo.
- Umhlaza wesisu - Njengomdlavuza we-pancreatic, umdlavuza wesisu uvame ukudibanisa nembali yokufumana unyango lwe-radiation ngaphantsi kwesithintelo.
- I-leukemia enesifo esibi kakhulu - I- leukemia njengomhlaza wesibini ayiqhelekanga njengoko yacingwa, kodwa umngcipheko usakhuphuka kubantu abasinda kwi-Hodgkin. njengoko kucinga ngaphambili. Iziyobisi ezifana ne-Cytoxan (cyclophosphamide) zithwala ingozi. I-Cytoxan yenye yeziyobisi kwi-BEACOPP chemotherapy.
Ezinye iiKhansela eziNyukayo KwiiHodgkin Lymphoma
- IMelanoma
- IMyelodysplastic syndrome (MDS)
- Umdlavuza womlomo okanye ulwimi, umhlaza wesifo somhlaza
- Umhlaza wesifo
- Umhlaza womhlaza
- Umhlaza wesifo kunye neengxaki zomdlavuza
- Umhlaza wesibeleko
- Umhlaza weTyroid
- Sarcoma Kaposi
Ingozi enkulu yeCancer Cancers ihlala nini?
Akuqinisekanga ukuba umngcipheko weekliniki zesekondari zihlala zingaphi, nangona kunjalo ukuba umngcipheko uhlala uphakamise ukuhlala kwintshona yobomi. Ngokuqhelekileyo, kubonakala ukuba umngcipheko ophezulu weekliniki zesekondari zenzeka kwishumi lesithathu emva kwonyango.
Izikhokelo zokuHlola iCarcer Secondary
Kukho ngoku kukho izikhokelo kwindawo yokuhlola ezinye i-cancer zesibini. Ezi zikhokelo zokusindisa zikhupha iingcebiso ezithile ezixhomekeke kwiminyaka yakho ekuxilongweni, iintlobo ezithile zonyango ozifumeneyo, kunye nobude bexesha ukususela ekugqityeni unyango. Kubalulekile ukuba wonke umntu oye wafumana isifo sikaHodgkin ukuba ahlolisise ezi khokelo aze axoxe nabo nge-oncologist yabo. Ukongezwa kule mi khombiso kufuneka kube nayiphi na into ebungozi okanye imbali yentsapho yomhlaza onayo.
Ukubeka iliso nokuQaphela kwangaphambili nokuQaphela iziMpawu
Nangona kukho izikhokelo ezikhoyo ekufunyanweni kwangoko kweekliniki zesibini, kubalulekile ukubonisa ukuba akukho okwenziweyo ukuhlola iimvavanyo ezifumanekayo ezininzi zeekresela ezonyuka kulabo abaneHodgkin lymphoma.
Ngokomzekelo, asinayo nayiphi indlela yokukhupha abantu rhoqo nge-non-Hodgkin lymphoma, umdlavuza oqhelekileyo emva kokonyango. Okwangoku, kubonakala kunengqiqo ukuba abo baseHodgkin lymphoma bafanele baqaphele iimpawu ze-non-Hodgkin lymphoma baze bafune unyango ukuba kukho na enye yale mpawu ifanele ivele.
Kuloo khansela apho izikhokelo zikhoyo, unokulindela utshintsho. Siqala ukuqonda ingozi yeekliniki zesibini, kwaye uphando oluninzi luye lwenziwa.
Kubaluleka koKhathalelo lwamayeza rhoqo emva kweHodgkin Lymphoma
Ukongezelela nayiphi na ukulandelelwa okucetyiswa yi-oncologist yakho ukufumanisa kwangaphambili i-cancer yeesibini, kubalulekile ukuqinisekisa ukuba usesikhathini "kwiziqhelo zokuhlola" eziqhelekileyo.
Amaxesha amaninzi xa uxhathisa umhlaza, ezinye iimeko zonyango ziqhutyelwa kwi-burner yangemuva (okanye zicima isitofu ngokupheleleyo). Ukuhlolwa kweemvavanyo ezifana ne-colonoscopy inokwehla. Kubantu abaninzi, into yokugqibela abayifunayo ukuyenza emva kokuzalisa unyango kukuba ube nokuvavanya ukuhlolwa komnye umhlaza!
Kwesinye inqaku, unokuba noyena nto ingabonakalisa uphawu lokuqala lomhlaza, kodwa ngokumalunga nento oye waphila ngayo, isibonakaliso sakho singabonakali konke okubalulekileyo. Abantu abanomdla kaninzi bafunda ukuhlala kunye nesantya okanye intlungu, kwaye phantse bonke abantu bafunda ukuhlala bekhathala. Kungaba nzima kakhulu ukwahlula ukukhathala ngenxa yengxaki entsha ekukhathaleni okuhlala kubonakala ngonaphakade emva kokunyangwa komhlaza. Mamela umzimba wakho kwaye uthembele emathunjini akho. Ukuba kukho into ebonakalayo eyahlukileyo, xela ugqirha wakho.
Ungayinciphisa njani Ingozi Yomdlavuza Wesibili?
Ukongezelela kwiimvavanyo zokuphonononga ugqirha wakho uncoma, ukufumana iindlela zokuphila ezinempilo kunokunciphisa umngcipheko wokuphucula umdlavuza wesibili. Oku kubandakanya:
- Ukutya ukutya okunempilo
- Ukugcina ubunzima obunempilo
- Ukuphepha ukutshaya
- Ukusebenzisa rhoqo
- Ukunciphisa ukusetyenziswa kotywala
- Ukulandela ukulungiswa kwempilo kunye nezikhokelo zokuhlola
Ukongeza, unokuba unqwenela ukujonga ezi ngcebiso malunga nokunciphisa umngcipheko womhlaza wekolon , ezi ngcebiso malunga nokunciphisa ingozi yomhlaza wamaphaphu , kunye nale ngcamango ekunciphiseni ingozi yomhlaza wesisu .
ILizwi
Kunokutshatyalaza ukufunda ukuba kukho umngcipheko weekliniki zesibini emva kwonyango lweHodgkin lymphoma, kodwa kukho izinto ezininzi onokuzenza ukuze unciphise umngcipheko wakho. Indlela yokuphila enempilo kunokuncedisa ukunciphisa umngcipheko wale khansa kunye neemeko zonyango eziqhelekileyo phakathi koluntu jikelele. Kubalulekile ukuthetha ne-oncologist yakho malunga nokuphononongwa okucetywayo kusekelwe kunyango oye wayenayo. Kwakhona ingcamango enhle yokuba nayo nayiphi na impawu emitsha ijongwe ngokukhawuleza. Olu dibana lokunciphisa umngcipheko wakho kwaye ukwandisa ithuba lokuba uya kufumana umhlaza kwimigangatho engaphaya kweyonyango inokuhamba ixesha elide ekwenzeni ukuba uhlale usinda noHodgkin lymphoma "olutsha oluqhelekileyo."
> Imithombo:
> Keegan, T., Bleyer, A., Rosenerg, A., Li, Q., noMnu Goldfarb. I-Second-Primary Inflammatory Neoplasms and Survival in Survival Adolescent and Young Adult Survivors. JAMA Oncology . 2017 Apreli 20. (Epub phambi kokuprinta).
> Norval, E., no-E. Raubenheimer. Izibhambathiso Zesibili kwi-Hodgkin Izifo: Ukuhlaziywa kweeNcwadi kunye neNgxelo yeTyala ngeLymphoma yesiLinnert yesiThili. Umbhalo we-Oral and Maxillofacial Pathology . 2014. 18 (iSiza 1): S90-5.
> Radford, J., noDongo Longo. Amanqaku angamaKrekhsi wesiBini emva koTyango lweHodgkin Lymphoma - Isizathu esiqhubekayo sokukhathazeka. I-New England Journal of Medicine . 2015. 373: 2572-2573.
> Rigter, L., Spaander, M., Iinyanga, uL. et al. I-Colorectal Cancer Surveillance kwi-Hodgkin Lymphoma Survivors kwiNgozi eyongeziweyo yeCrorectal Cancer-Related Related: I-Design Design. BMC Cancer . 2017. 17 (1): 112.
> Schaapveld, M., Aleman, B., van Eggermond, A. et al. Umngcipheko weCancer Second for Up to 40 Years after Treatment for Hogkin's Lymphoma. I-New England Journal of Medicine . 2015. 373: 2499-2511.