Izikhokelo ezivela kwi-AHS / AAN
Ukugcina idayari yentloko yinto eninzi kuthi ababenzi-migraine bayenzayo ukuze bachonge iziphumo zethu zokubangela i-migraine. Ngokulondoloza ngokucokisekileyo ukulandelela kunye nokuphepha ukukhupha kwethu, sithemba ukukhusela ukuhlaselwa kwe-migraine. Nangona kunjalo, masingathethi, nangona sithintela ukuthintela, abaninzi abaxhamli bafuna imithi yansuku zonke ukukhusela ezi ntloko zesoyika.
Yintoni iMicraine Preventive Medication?
Imithi yokukhusela ithathwa imihla ngemihla ukunciphisa inani, ubunzima, kunye nobude bokuhlaselwa kwe-migraine, kunye nokunciphisa ukukhubazeka okulethwe ziintsholongwane rhoqo. Ngokuqhelekileyo zisetyenziselwa abo banesifo esingapheliyo , kodwa singasetyenziselwa i-epradic migraineurs.
Imizekelo yezibonakaliso ezinokwenzeka (ngaphandle kwe-migraine engapheliyo) kumachiza okukhusela ziquka: ukuchasana kwimiqathango yokwenza isisu kunye / okanye umgangatho onobungozi wobomi okanye ukusebenza kwansuku zonke. Zininzi iintlobo ze-migraine ezifana ne- hemiplegic migraine okanye i- basilar migraine inokubonisa ukuba imithi yokukhusela.
I-American Headache Society (AHS) kunye ne-American Academy ye-Neurology (AAN) isungulwe izikhokelo kumachiza ancomayo ukukhusela i-episodic migraine-migraines engabikhoyo emva kweentsuku ezili-15 ngenyanga. Sekunjalo, uninzi lwamachiza afanayo lusetyenziswe njengolukhuseleko kulabo abanesifo esingapheliyo.
Iimpawu zokuthintela imithi yokuthintela imithi.
- Ama-antihypertensives (i-blood pressure agents)
- Ukuxhatshazwa
- Anticonvulsants
- Petasites (Butterbur)
Uxinzelelo lweGazi lokuNciphisa iMida yokuVimbela iMigraines
Zininzi iintlobo zamachiza ezisetyenziselwa ukuthintela ukuhlaselwa kwe-migraine. Iingcipheko zegazi zokunciphisa , ikakhulukazi i-beta-blockers, zisetyenziswe ngokuqhelekileyo.
I-AHS / AAN inqume ukuba i-metoprolol, propranolol, kunye ne-timolol yinqanaba A machiza. Oku kuthetha ukuba bathathwa "ngempumelelo" yokuthintela i-migraine, ngelixa i-atenolol iyinkunkuma yeNqanaba B okanye "mhlawumbi isebenzayo."
I-Beta-blockers kufuneka isetyenziswe ngokulumkileyo kulabo abane-asthma kunye nesifo sikashukela kwaye abachasene nalabo abane-bradycardia yesifo (izinga lentliziyo eliphantsi). Ezinye iziphumo ezichaphazelekayo ze-beta blockers ziquka i-mood ephantsi, ukukhathala, kunye ne-erectile dysfunction.
Olunye uxinzelelo lwegazi olunjenge-verapamil, i -blocker ye-calcium-channel , ngamanye amaxesha kusetyenziswa ukukhusela imigraines, nangona ubungqina besayensi abasemva kwayo abuqine njengabo beta-blockers. Izikhokelo ze-AHS / AAN 2012 zibonise i-verapamil njenge-"U", ithetha ukuba "akukho lwazi olufanelekileyo lokuxhasa okanye ukuphikisa ukusebenzisa i-migraine prophylaxis." Ama-antihypertensias lisinopril kunye ne-candesartan (ezaziwa ngokuba yi-ACE inhibitors) zahlulwa njengezidakamizwa zeNqanaba C I-AHS / AAN, oku kuthetha ukuba "mhlawumbi isebenzayo" esekelwe kwisifundo esinye.
Iingxaki zokuxhatshazwayo ukukhusela ii-Epradic Migraines
Ukuxhatshazwa kweengxaki , ngakumbi i-amitriptyline kunye ne-venlafaxine, zibhekwa njengezilwanyana zeNqanaba B ("mhlawumbi zisebenza") zokuthintela i-migraine. I-Venlafaxine (Effexor) yi-serotonin-norepinephrine yokuvuselela i-inhibitor.
I-Amitriptyline (Elavil) yinto exhaphakileyo ye-tricyclic antidepressant esebenza ngokunqanda ukuphindaphinda kwe-neurotransmitters ezimbini kwingqondo, i-serotonin kunye ne-norepinephrine. Ingumgulo wokutshatyalaliswa kwaye uyathathwa ngexesha lokulala.
I-Amitriptyline iphinda ivimbele i-acetylcholine receptors kunye ne- histamine receptors kwingqondo, kubangele iimiphumo ezinobungozi be-anticholinergic njengomlomo owomileyo, ukuzitywa kunye nokugcinwa kwamanzi. Kwakhona kunokubangela ukuzuza ubunzima nokudideka. Ekugqibeleni, i-amitriptyline ingaba nemiphumo emibi kakhulu njengokwenza i-cardiac conduction engafanelekiyo, ngoko kufuneka igwenywe kulabo abanesifo senhliziyo.
I-Anticonvulsants ukukhusela ii-Migraines ze-episodic
Ngokwe- anticonbulsants , i-American Academy ye-Neurology yagqiba ukuba iimveliso ze-valproate, i-divalproex sodium, kunye ne-sodium valproate, kunye ne-topiramate (topamax) zisebenza (iNqanaba A iziyobisi) ekukhuseleni i-migraines. Iziphumo eziphambili ze-topiramate ziquka
- ukuhla ukusinda
- ukukhathala
- ukungcola
- paresthesias
- ukungasebenzi kwengqondo
- ukuguqulwa kwesininzi.
Imiphumo emibi yamachiza e-valproate zibandakanya: ukufumana isisindo, inambuzane, inyikima, kunye neentlungu zokulahleka.
I-Butterbur kunye namanye amayeza okukhusela i-Epradic Migraine
I-Petasites (butterbur) yenye yeNqanaba leMveliso eliphumelelayo lokuthintela imitha. Le yile mveliso yonyango okanye enye imithi ethathwa kabini imihla ngemihla. Impembelelo yecala eliphambili lugqugquzelekayo oluncinci lwe-GI, ngokugqithiseleyo.
Ezinye izidakamizwa zamanqanaba eBrazil okanye iziyobisi "mhlawumbi zisebenzayo" zokuthintelwa kwemigraine, njengoko kuphawulwe nguMbutho weNtloko waseMelika kunye ne-American Academy of Neurology kubandakanya:
- Ezinye iindlela zokwelapha : i-feverfew, i-magnesium, ne-riboflavin
- Ezinye i-NSAID (ibuprofen, naproxen)
- Amanye ama-triptans (naratriptan, zolmitriptan): Nceda uqaphele , oku kuboniswe ukuba kube yimigraines yokuya esikhathini .
Ngaphantsi
Ngamanye amaxesha imithi yokukhusela ibonakaliswe ukunciphisa inani, ubunzima, ubude kunye nokukhubazeka ezihambelana nemigraines. Ngokutsho kweengcali, i-beta-blockers ethile (i-metoprolol, timolol, propanolol), i-anticonvulsants (i-valproate iimveliso, i-topiramate), kunye ne-butterbur supplement i-butterbur iye yasungulwa njengeNqanaba A okanye "isebenzayo" njengemithi yokukhusela i-epradic migraines.
Ukuba ufumanisa ukuba i-migraines yakho inempembelelo ekusebenzeni kwakho kwansuku zonke okanye umgangatho wobomi, xela nodokotela wakho malunga neenzuzo kunye neengozi zokuqala imithi yokukhusela i-migraine-kunokuthi ube yinto oyifunayo okwesikhashana de ube unokunquma ukuhamba kwakho kwe-migraine okanye fumana enye indlela yokuhlangabezana nayo.
Imithombo:
Bajwa Z, Sabahat A. Ukukhusela ukukhutshwa kwe-migraine kubantu abadala. Ku: U-UpToDate, iBasow DS (Ed), UpToDate, Waltham, MA, 2013.
I-Lipton RB, iGöbel H, i-Einhäupl KM, uWilks K, i-Mauskop A. I-Petasites hybridus ingcambu (butterbur) yonyango olukhuselekileyo lokukhusela i-migraine. Neurology . 2004 Umhla wama-28; 63 (12): 2240-4.
I-Loder E, iBurch R, i-Rizzoli P. Izikhokelo ze-AHS / AAN ze-2012 zokuthintelwa kwe-epradic migraine: isishwankathelo kunye nokuthelekiswa nezinye izikhokelo zonyango zamuva. Intloko . 2012: 52: 930-45 .
I-Podrid P. Imiphumo emibi yecala ye-beta blockers. Ku: UpToDate, iBasow DS (Ed), UpToDate, Waltham, MA, 2013.
ISilberstein SD, i-Holland S, i-Freitag F, et al. Uhlaziyo olusekelwe kwizikhokelo-mboniso: unyango lwe-pharmacologic ye-episodic migraine yokuthintela kubantu abadala: ingxelo yeCommittee Standards Quit of the American Academy of Neurology kunye ne-American Headache Society. Neurology 2012; 78: 1337.
INKCAZELO: Ulwazi olukule ndawo lusezinjongo zemfundo kuphela. Akufanele isetyenziswe njengendawo yokunyamekelwa ngumntu ogqirha. Nceda ubone ugqirha wakho ukuze ufumane unyango kunye nonyango malunga nayiphi na impawu okanye imeko yonyango .